Document And Entity Information [Abstract] Document And Entity Information [Abstract] Document Type Document Type Amendment Flag Amendment Flag Document Period End Date Document Period End Date Document Fiscal Year Focus Document Fiscal Year Focus Document Fiscal Period Focus Document Fiscal Period Focus Trading Symbol Trading Symbol Entity Registrant Name Entity Registrant Name Entity Central Index Key Entity Central Index Key Current Fiscal Year End Date Current Fiscal Year End Date Entity Current Reporting Status Entity Filer Category Entity Filer Category Entity Common Stock, Shares Outstanding Entity Common Stock, Shares Outstanding Condensed Consolidated Balance Sheets Assets [Abstract] Assets Assets, Current [Abstract] Current assets: Cash and Cash Equivalents, at Carrying Value Cash and cash equivalents at end of period Cash and cash equivalents at beginning of period Cash and cash equivalents Cash and cash equivalents, Amortized Cost Available-for-sale Securities, Debt Securities, Current Short-term investments Accounts Receivable, Net Accounts receivable Contract with Customer, Asset, Net, Current Unbilled license revenue Prepaid Expense and Other Assets, Current Prepaid expenses and other current assets Assets, Current Current assets Total current assets Property, Plant and Equipment, Net Property and equipment, net Other Assets, Noncurrent Other assets Assets Total assets Liabilities and Equity [Abstract] Liabilities and stockholders' equity Liabilities, Current [Abstract] Current liabilities: Accounts Payable, Current Accounts payable Employee-related Liabilities, Current Accrued compensation and benefits Contract with Customer, Liability, Current Uncharged license fees Accrued Liabilities and Other Liabilities Accrued and other liabilities Accrued liabilities and other liabilities Liabilities, Current Current liabilities Total current liabilities Loans Payable, Noncurrent Loan payable, long term Other Liabilities, Noncurrent Other long-term liabilities Liabilities Total liabilities Commitments and Contingencies Commitments and contingencies Stockholders' Equity Attributable to Parent [Abstract] Stockholders' equity: Preferred Stock, Value, Issued Preferred stock, $0.0001 par value; 5,000,000 shares authorized; no shares issued and outstanding as of June 30, 2018 and December 31, 2017, respectively. Common Stock, Value, Issued Common stock, $0.0001 par value; 300,000,000 shares authorized; 62,053,751 and 47,534,979 shares issued and outstanding as of June 30, 2018 and December 31, 2017, respectively. Additional Paid in Capital, Common Stock Additional paid-in capital Retained Earnings (Accumulated Deficit) Accumulated deficit Accumulated Other Comprehensive Income (Loss), Net of Tax Accumulated other comprehensive loss Stockholders' Equity Attributable to Parent Total stockholders' equity Liabilities and Equity Total liabilities and stockholders' equity Preferred Stock, Par or Stated Value Per Share Preferred stock, par value Preferred Stock, Shares Authorized Preferred stock, shares authorized Preferred Stock, Shares Issued Preferred stock, shares issued Preferred Stock, Shares Outstanding Preferred stock, shares outstanding Common Stock, Par or Stated Value Per Share Common stock, par value Common Stock, Shares Authorized Common stock, shares authorized Common Stock, Shares, Issued Common stock, shares issued Common stock issued Common Stock, Shares, Outstanding Common stock, shares outstanding Condensed Consolidated Statements of Operations and Comprehensive Loss Statement [Table] Statement [Line Items] Revenues [Abstract] Revenue: Revenues Total revenues Revenue Cost of Revenue Cost of revenue Gross Profit Gross profit Operating Expenses [Abstract] Operating expenses: Research and Development Expense Research and development General and Administrative Expense General and administrative Operating Expenses Total operating expenses Operating Income (Loss) Loss from operations Nonoperating Income (Expense) Other income (expense), net Income (Loss) from Continuing Operations before Income Taxes, Noncontrolling Interest Loss before provision for income taxes Income Tax Expense (Benefit) Provision for income taxes Net Income (Loss) Attributable to Parent Net loss Net loss Earnings Per Share, Basic and Diluted Net loss per common share, basic and diluted Net loss per share - basic and diluted Weighted Average Number of Shares Outstanding, Basic and Diluted Shares used in computing net loss per share - basic and diluted Weighted average common shares outstanding - basic and diluted Comprehensive Income (Loss), Net of Tax, Attributable to Parent [Abstract] Comprehensive loss: Other Comprehensive Income (Loss), Available-for-sale Securities Adjustment, Net of Tax, Portion Attributable to Parent Unrealized (loss) gain on available-for-sale securities, net of tax Comprehensive Income (Loss), Net of Tax, Attributable to Parent Comprehensive loss Condensed Consolidated Statements of Cash Flows Net Cash Provided by (Used in) Operating Activities, Continuing Operations [Abstract] Operating activities Adjustments to Reconcile Net Income (Loss) to Cash Provided by (Used in) Operating Activities [Abstract] Adjustments to reconcile net loss to net cash used in operating activities: Depreciation Depreciation expense Amortization of Debt Issuance Costs Amortization of deferred financing costs Cost of Services, Amortization Amortization of deferred compensation for services Accretion (Amortization) of Discounts and Premiums, Investments Amortization of premium on investment securities Share-based Compensation Stock-based compensation Non-cash interest expense. Noncash Interest Expense Non-cash interest expense relating to loan payable Increase (Decrease) in Operating Capital [Abstract] Changes in operating assets and liabilities: Increase (Decrease) in Accounts Receivable Accounts receivable Increase (Decrease) in Prepaid Expense and Other Assets Prepaid expenses and other assets Increase (Decrease) in Accounts Payable Accounts payable Increase (Decrease) in Employee Related Liabilities Accrued compensation and benefits Increase (Decrease) in Other Accrued Liabilities Accrued and other liabilities Net Cash Provided by (Used in) Operating Activities, Continuing Operations Net cash used in operating activities Net Cash Provided by (Used in) Investing Activities, Continuing Operations [Abstract] Investing activities Proceeds from Maturities, Prepayments and Calls of Short-term Investments Proceeds from maturities of investments Proceeds from Sale of Other Investments Sales and redemptions of investments Payments to Acquire Short-term Investments Purchases of investments Payments to Acquire Property, Plant, and Equipment Purchases of property and equipment Net Cash Provided by (Used in) Investing Activities, Continuing Operations Net cash (used in) provided by investing activities Net Cash Provided by (Used in) Financing Activities, Continuing Operations [Abstract] Financing activities Proceeds from Debt, Net of Issuance Costs Proceeds from loan payable, net of issuance costs Net proceeds from the loan Proceeds from Issuance Initial Public Offering Proceeds from underwritten public offering, net of issuance costs Proceeds from Issuance of Common Stock Proceeds from issuance of common stock, net of issuance costs Net proceeds Proceeds from Issuance of Shares under Incentive and Share-based Compensation Plans, Including Stock Options Proceeds from issuance of common stock under stock plans Net Cash Provided by (Used in) Financing Activities, Continuing Operations Net cash provided by financing activities Cash and Cash Equivalents, Period Increase (Decrease) Net decrease in cash and cash equivalents Supplemental Cash Flow Information [Abstract] Supplementary disclosure of non-cash financing information: Represents the non-cash issuance of derivative in connection with issuance of loan payable. Issuance of Derivative in Connection with Issuance of Loan Payable Issuance of derivative in connection with issuance of loan payable Organization and Basis of Presentation Organization, Consolidation, Basis of Presentation, Business Description and Accounting Policies [Text Block] Organization and Basis of Presentation Summary of Significant Accounting Policies Significant Accounting Policies [Text Block] Summary of Significant Accounting Policies Cash, Cash Equivalents and Investments Cash, Cash Equivalents, and Short-term Investments [Text Block] Cash, Cash Equivalents and Investments Fair Value Measurements Fair Value Disclosures [Text Block] Fair Value Measurements Borrowings Debt Disclosure [Text Block] Borrowings Shareholders Equity Stockholders' Equity Note Disclosure [Text Block] Shareholders Equity Stock-Based Compensation Disclosure of Compensation Related Costs, Share-based Payments [Text Block] Stock-Based Compensation Net Loss Per Share Earnings Per Share [Text Block] Net Loss Per Share Accrued and Other Liabilities Accounts Payable, Accrued Liabilities, and Other Liabilities Disclosure, Current [Text Block] Accrued and Other Liabilities NA. Collaboration and Licensing Agreements Collaborative Arrangement Disclosure [Text Block] Collaboration and Licensing Agreements Contingencies Commitments and Contingencies Disclosure [Text Block] Contingencies Use of Estimates, Policy [Policy Text Block] Use of Estimates Accrued research and development expenses policy. Accrued Research and Development Expenses Policy [Policy Text Block] Accrued Research and Development Expenses Disclosure of accounting policy for revenue from contract with customer. Revenue from Contract with Customer [Policy Text Block] Revenue Recognition Reclassification, Policy [Policy Text Block] Reclassification New Accounting Pronouncements, Policy [Policy Text Block] Recent Accounting Pronouncements Fair Value Measurement, Policy [Policy Text Block] Fair Value Measurements New Accounting Pronouncements or Change in Accounting Principle [Table] New Accounting Pronouncements or Change in Accounting Principle [Line Items] Impact of Adoption Schedule of New Accounting Pronouncements and Changes in Accounting Principles [Table Text Block] Schedule of adjustments of topic 606 Cash, Cash Equivalents and Investments [Table Text Block] Schedule of Securities Classified as Cash, Cash Equivalents and Short-term Investments Schedule of Fair Value, Assets and Liabilities Measured on Recurring Basis [Table Text Block] Summary of Fair Value Measurements of Company's Financial Assets and Liabilities Schedule of Maturities of Long-term Debt [Table Text Block] Schedule of future debt payment obligations Schedule of Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Table Text Block] Summary of Stock-Based Compensation Expense Recognized Schedule of Earnings Per Share, Basic and Diluted [Table Text Block] Computation of Basic and Diluted Loss Per Share Attributable to Common Stockholders Schedule of Accounts Payable and Accrued Liabilities [Table Text Block] Schedule of Accrued Liabilities and Other Liabilities Number of Operating Segments Number of operating segments Prior Period Reclassification Adjustment Amount reclassified from financing activities to operating activities Cash and cash equivalents and short term investments. Cash Cash Equivalents And Short Term Investments [Table] Major Types of Debt and Equity Securities [Axis] Major Types Of Debt And Equity Securities [Domain] Major Types of Debt and Equity Securities [Domain] U S Treasury Securities [Member] U.S. Treasury Securities [Member] Corporate Debt Securities [Member] Corporate Bonds [Member] Commercial Paper Not Included With Cash And Cash Equivalents [Member] Commercial Paper (Investments) [Member] Asset Backed Securities [Member] Asset-Backed Securities [Member] Cash and Cash Equivalents [Axis] Restricted Cash And Cash Equivalents Cash And Cash Equivalents [Member] Cash and Cash Equivalents [Domain] Cash [Member] Cash [Member] Money Market Funds [Member] Money Market Funds [Member] Commercial Paper [Member] Commercial Paper (Cash Equivalents) [Member] Cash and cash equivalents and short term investments. Cash Cash Equivalents And Short Term Investments [Line Items] Cash Equivalents, at Carrying Value Cash and cash equivalents, at Carrying Value Cash and Cash Equivalents, Fair Value Disclosure Cash and cash equivalents, Fair Value Available-for-sale Securities, Amortized Cost Basis Short-term investments, Amortized Cost Available-for-sale Securities, Accumulated Gross Unrealized Gain, before Tax Short-term investments, Gross Unrealized Gains Available-for-sale Securities, Accumulated Gross Unrealized Loss, before Tax Short-term investments, Gross Unrealized Losses Available-for-sale Securities Short-term investments, Fair Value Cash, Cash Equivalents, and Short-term Investments Cash equivalents and short-term investments, Amortized Cost Cash, cash equivalents and short term investments gross unrealized gains. Cash Cash Equivalents And Short Term Investments Gross Unrealized Gains Cash equivalents and short-term investments, Gross Unrealized Gains Cash, cash equivalents and short term investments gross unrealized losses. Cash Cash Equivalents And Short Term Investments Gross Unrealized Losses Cash equivalents and short-term investments, Gross Unrealized Losses Cash, cash equivalents and short term investments fair value disclosure. Cash Cash Equivalents And Short Term Investments Fair Value Disclosure Cash equivalents and short-term investments, Fair Value Range [Axis] Range [Member] Range [Domain] Maximum [Member] Maximum [Member] Available for sale securities contractual maturity period. Available For Sale Securities Contractual Maturity Period Available for sale securities contractual maturity period Available-for-sale Securities, Continuous Unrealized Loss Position, 12 Months or Longer, Accumulated Loss Investment in continuous unrealized loss position for more than one year Fair Value Measurements, Recurring and Nonrecurring [Table] Asset Class [Axis] Fair Value Assets Measured On Recurring Basis Unobservable Input Reconciliation By Asset Class [Domain] Asset Class [Domain] Domestic Corporate Debt Securities Including Cash Equivalents [Member] Domestic Corporate Debt Securities Including Cash Equivalents [Member] Corporate Bonds [Member] Commercial Paper Cash Equivalents Including Securities [Member] Commercial Paper Cash Equivalents Including Securities [Member] Commercial Paper [Member] Measurement Frequency [Axis] Fair Value Measurement Frequency [Domain] Fair Value, Measurement Frequency [Domain] Fair Value Measurements Recurring [Member] Fair Value, Recurring [Member] Fair Value, Hierarchy [Axis] Fair Value Measurements Fair Value Hierarchy [Domain] Fair Value Hierarchy [Domain] Fair Value Inputs Level1 [Member] Level 1 [Member] Fair Value Inputs Level2 [Member] Level 2 [Member] Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] Fair Value Measurements Assets, Fair Value Disclosure [Abstract] Assets: Assets, Fair Value Disclosure Assets at fair value Liabilities, Fair Value Disclosure [Abstract] Liabilities Financial and Nonfinancial Liabilities, Fair Value Disclosure Derivative liability Estimated fair value of Exit Fee Fair Value, Assets, Level 1 to Level 2 Transfers, Amount Transfer of assets from Level 1 to Level 2 Fair Value, Assets, Level 2 to Level 1 Transfers, Amount Transfer of assets from Level 2 to Level 1 Business Exit Costs Exit Fee Represents the exit fee payable term. Exit Fee Payable Term Exit fee payable term (in years) Amount of potential milestone payment as a result of FDA approval. Fair Value Inputs, Potential Milestone Payment as Result of Food and Drugs Administration Approval Potential payment to Solar Capital Ltd. and Western Alliance Bank The reasonably possible percentage of the increase in the designated risk component used to determine the value of the financial instrument. Excludes defined benefit plan obligations. Percentage of Reasonably Possible Increase in Risk Assumption Percentage of increase in risk component The reasonably possible percentage of the decrease in the designated risk component used to determine the value of the financial instrument. Excludes defined benefit plan obligations. Percentage of Reasonably Possible Decrease in Risk Assumption Percentage decrease in risk component The increase (decrease) in a financial instrument as a result of an increase in a designated risk component that was reasonably possible at the end of the reporting period. Excludes defined benefit plan obligations. Increase (Decrease) in Financial Instrument Due to Reasonably Possible Increase in Designated Risk Component Fair value fluctuation due to increase in risk component The increase (decrease) in a financial instrument as a result of an decrease in a designated risk component that was reasonably possible at the end of the reporting period. Excludes defined benefit plan obligations. Increase (Decrease) in Financial Instrument Due to Reasonably Possible Decrease in Designated Risk Component Fair value fluctuation due to decrease in risk component Schedule of Long-term Debt Instruments [Table] Debt Instrument [Line Items] Term Loans Long-term Debt, Gross Amount of term loan facility Debt Instrument, Basis Spread on Variable Rate Floating interest rate The percentage of premium payable on principal amount of the term loan at or before maturity redemption. Percentage of Premium Payable on Redemption of the Term Loan Percentage of premium payable on redemption of the term loan The amount of fee payable upon closing of the term loan. Fee Payable upon Closing of the Term Loan Amount of fee payable upon closing of the term loan The percentage of fee payable on prepayment of debt. Prepayment Fee Percentage Prepayment fee (as a percent) The percentage on the term loan payable as exit fee under the terms of debt agreement. Percentage of Exit Fee Exit fee (as a percent) The expiration term of exit fee, in PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents the reported fact of one year, five months, and thirteen days. Exit Fee Expiration Term Expiration term of exit fee Minimum unrestricted cash and cash equivalents to be maintained under the terms of debt agreement. Minimum Unrestricted Cash and Cash Equivalents to be Maintained Minimum unrestricted cash and cash equivalents to be maintained Percentage of additional default interest rate on the event of default. Default Interest Rate Additional default interest rate Long-term Debt, Fiscal Year Maturity [Abstract] Future debt payment obligations Long-term Debt, Maturities, Repayments of Principal in Year Three 2020 Long-term Debt, Maturities, Repayments of Principal in Year Four 2021 Long-term Debt, Maturities, Repayments of Principal in Year Five 2022 Long-term Debt Total Debt Instrument, Unamortized Discount (Premium) and Debt Issuance Costs, Net Less: Unamortized discount and debt issuance costs The unaccreted value of final fee of debt instrument. Debt Instrument, Unaccreted Value, Final Fee Less: Unaccreted value of final fee Subsidiary or Equity Method Investee, Sale of Stock by Subsidiary or Equity Investee [Table] Subsidiary, Sale of Stock [Line Items] Share Price Purchase price Public offering price Purchase price of single share of a company. Share Purchase Price Purchase price Number of days given to the underwriter to sell additional shares over the initial allotment, in PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents the reported fact of one year, five months, and thirteen days. Number of Days to Underwriter to Sell Additional Common Shares Number of days to underwriters to sell additional common shares Share-based Compensation Arrangement by Share-based Payment Award, Options Outstanding, Weighted Average Exercise Price, and Additional Disclosures [Abstract] Share-based Compensation Arrangement by Share-based Payment Award, Options Outstanding, Weighted Average Exercise Price, and Additional Disclosures [Abstract] Schedule of Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Table] Income Statement Location [Axis] Income Statement Location [Domain] Income Statement Location [Domain] Research And Development Expense [Member] Research and Development [Member] General And Administrative Expense [Member] General and Administrative [Member] Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost [Line Items] Allocated Share-based Compensation Expense Stock-based compensation Schedule of Share-based Compensation Arrangements by Share-based Payment Award [Table] Plan Name [Axis] Plan Name [Domain] Plan Name [Domain] Employee Stock Purchase Plan [Member] Employee Stock Purchase Plan [Member] Employee Stock Purchase Plan [Member] Award Type [Axis] Share Based Compensation Arrangements By Share Based Payment Award Award Type And Plan Name [Domain] Equity Award [Domain] Employee Stock Option [Member] Options to Purchase Common Stock [Member] Restricted Stock Units R S U [Member] Restricted Stock Units (RSUs) [Member] Performance based restricted stock units. Performance Based Restricted Stock Units [Member] Performance-Based Restricted Stock Units (PRSUs) [Member] Share-based Compensation Arrangement by Share-based Payment Award [Line Items] Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Vested in Period Number of vested shares Share-based Compensation Arrangement by Share-based Payment Award Accelerated Compensation Cost Recognized stock-based compensation related expense in connection with vesting of award granted Employee Service Share-based Compensation, Nonvested Awards, Compensation Cost Not yet Recognized Unrecognized stock based compensation expense Employee Service Share-based Compensation, Nonvested Awards, Compensation Cost Not yet Recognized, Period for Recognition Unrecognized stock based compensation expense, weighted-average remaining recognition period Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercises in Period Number of options exercised Proceeds from Stock Options Exercised Proceeds from exercise of stock options Stock Issued During Period, Shares, Restricted Stock Award, Net of Forfeitures Number of shares issued upon vesting of restricted stock units Stock Issued During Period, Shares, Employee Stock Purchase Plans Number of shares issued under ESPP Stock Issued During Period, Value, Employee Stock Purchase Plan Proceeds Stock Issued During Period, Shares, Issued for Services Issuance of common stock for services (Shares) Stock Issued During Period, Value, Issued for Services Issuance of common stock for services, amount Net Income (Loss) Attributable to Parent [Abstract] Numerator: Weighted Average Number of Shares Outstanding Reconciliation [Abstract] Denominator: Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount Anti-dilutive securities excluded from computation of diluted net loss per share attributable to common stockholders Accrued clinical and non-clinical expenses. Accrued Clinical And Non-clinical Expenses Accrued clinical and non-clinical expenses Accrued contract manufacturing costs. Accrued Contract Manufacturing Costs Accrued contract manufacturing Derivative Liability, Current Derivative liability Accrued professional and consultant fees current. Accrued Professional And Consultant Fees Current Accrued professional and consulting services Other Liabilities, Current Other Schedule of Collaborative Arrangements and Non-collaborative Arrangement Transactions [Table] Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] Proceeds from License Fees Received Upfront payment received The amount of development milestones payment to be received under collaborative arrangements. Collaborative Arrangement Development Milestones Payment to be Received Development milestones The amount of commercialization milestones payment to be received under collaborative arrangements. Collaborative Arrangement Commercialization Milestones Payment to be Received Commercialization milestones Represents the amount of future development and commercialization milestone under collaborative arrangements. Collaborative Arrangement Future Development and Commercialization Milestones Future development milestones Represents the threshold percentage of net sales for tiered royalties. Threshold Percentage Of Sales For Tiered Royalties Threshold percentage of net sales for tiered royalties The amount of upfront payments and development and sales milestones payment to be received under collaborative arrangements. Collaborative Arrangement Up-front Payment and Development and Sales Milestones Payment to be Received Total payments, including an up-front payment and development and sales milestones to be received Products and Services [Axis] Products And Services [Domain] Products and Services [Domain] Right to use intangible asset. Intangible asset includes, but is not limited to, patent, copyright, technology, manufacturing process, software or trademark. License [Member] Licensing Represents the information pertaining to revenues from other product or services. Other Product Or Services Revenue [Member] Other Adjustments for New Accounting Pronouncements [Axis] Type Of Adoption [Member] Type of Adoption [Domain] Accounting Standards Update201409 [Member] ASU 2014-09 Initial Application Period Cumulative Effect Transition [Axis] Initial Application Period Cumulative Effect Transition [Domain] Initial Application Period Cumulative Effect Transition [Domain] Difference Between Revenue Guidance In Effect Before And After Topic606 [Member] Adjustments Calculated Under Revenue Guidance In Effect Before Topic606 [Member] Before topic 606 Product [Member] Product supply Debt Instrument [Axis] Debt Instrument Name [Domain] Debt Instrument, Name [Domain] Represents the information pertaining to Solar Capital and Western Alliance Bank Loan Agreement. Solar Capital And Western Alliance Bank Loan Agreement [Member] Solar Capital and Western Alliance Bank Loan Agreement [Member] Balance Sheet Location [Axis] Balance Sheet Location [Domain] Balance Sheet Location [Domain] Other Current Liabilities [Member] Other Current Liabilities Fair Value Inputs Level3 [Member] Level 3 Variable Rate [Axis] Variable Rate [Domain] Variable Rate [Domain] London Interbank Offered Rate L I B O R [Member] LIBOR Debt Instrument, Redemption, Period [Axis] Debt Instrument Redemption Period [Domain] Debt Instrument, Redemption, Period [Domain] This member represents redemption of debt at maturity date under the terms of the debt agreement. At Maturity [Member] At Maturity Debt Instrument Redemption Period One [Member] Prior to first anniversary of closing date Debt Instrument Redemption Period Two [Member] After first anniversary of closing date This member represents period of redemption of debt after second anniversary to maturity date under the terms of the debt agreement. After Second Anniversary To Maturity Date [Member] After second anniversary to maturity date Sale of Stock [Axis] Sale Of Stock Name Of Transaction [Domain] Sale of Stock [Domain] Represents information pertaining to common stock issuance May 2018 offering. Common Stock Issuance May2018 Offering [Member] Offering Over Allotment Option [Member] Underwriters option Counterparty Name [Axis] Repurchase Agreement Counterparty Name [Domain] Counterparty Name [Domain] This member stands for Kyowa Hakko Kirin. Kyowa Hakko Kirin [Member] Kyowa Hakko Kirin [Member] This member stands for Shanghai Fosun Pharmaceutical Industrial Development. Shanghai Fosun Pharmaceutical Industrial Development [Member] Shanghai Fosun Pharmaceutical Industrial Development [Member] Astra Zeneca [Member] Astra Zeneca [Member] Astra Zeneca [Member] Represents information pertaining to Knight Therapeutics Inc. Knight Therapeutics Inc [Member] Knight Therapeutics Inc [Member] Type of Arrangement and Non-arrangement Transactions [Axis] Arrangements And Nonarrangement Transactions [Member] Arrangements and Non-arrangement Transactions [Domain] Represents information pertaining to development and commercialization milestone. Development And Commercialization [Member] Development And Commercialization [Member] Represents information pertaining to termination agreement. Termination Agreement [Member] Termination Agreement [Member]