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Fair Value Measurements link:presentationLink link:calculationLink link:definitionLink 0000010 - Disclosure - Inventory link:presentationLink link:calculationLink link:definitionLink 0000011 - Disclosure - Product Revenue, Net link:presentationLink link:calculationLink link:definitionLink 0000012 - Disclosure - Collaboration and Licensing Agreements link:presentationLink link:calculationLink link:definitionLink 0000013 - Disclosure - Deferred Royalty Obligation Related To The Sale Of Future Royalties link:presentationLink link:calculationLink link:definitionLink 0000014 - Disclosure - Borrowing link:presentationLink link:calculationLink link:definitionLink 0000015 - Disclosure - Derivative Liability link:presentationLink link:calculationLink link:definitionLink 0000016 - Disclosure - Leases link:presentationLink link:calculationLink link:definitionLink 0000017 - Disclosure - Stockholders' Equity link:presentationLink link:calculationLink link:definitionLink 0000018 - Disclosure - Equity Incentive Plans link:presentationLink link:calculationLink link:definitionLink 0000019 - Disclosure - Restructuring link:presentationLink link:calculationLink link:definitionLink 0000020 - Disclosure - Net Loss Per Share link:presentationLink link:calculationLink link:definitionLink 0000021 - Disclosure - Contingencies link:presentationLink link:calculationLink link:definitionLink 0000022 - Disclosure - Subsequent Events link:presentationLink link:calculationLink link:definitionLink 0000023 - Disclosure - Organization and Basis of Presentation (Policies) link:presentationLink link:calculationLink link:definitionLink 0000024 - Disclosure - Cash, Cash Equivalents and Investments (Tables) link:presentationLink link:calculationLink link:definitionLink 0000025 - Disclosure - Fair Value Measurements (Tables) link:presentationLink link:calculationLink link:definitionLink 0000026 - Disclosure - Inventory (Tables) link:presentationLink link:calculationLink link:definitionLink 0000027 - Disclosure - Product Revenue, Net (Tables) link:presentationLink link:calculationLink link:definitionLink 0000028 - Disclosure - Collaboration and Licensing Agreements (Tables) link:presentationLink link:calculationLink link:definitionLink 0000029 - Disclosure - Borrowing (Tables) link:presentationLink link:calculationLink link:definitionLink 0000030 - Disclosure - Derivative Liability (Tables) link:presentationLink link:calculationLink link:definitionLink 0000031 - Disclosure - Leases (Tables) link:presentationLink link:calculationLink link:definitionLink 0000032 - Disclosure - Equity Incentive Plans (Tables) link:presentationLink link:calculationLink link:definitionLink 0000033 - Disclosure - Net Loss Per Share (Tables) link:presentationLink link:calculationLink link:definitionLink 0000034 - Disclosure - Organization and Basis of Presentation (Details) link:presentationLink link:calculationLink link:definitionLink 0000035 - Disclosure - Cash, Cash Equivalents and Investments - Securities Classified as Cash, Cash Equivalents and Investments (Details) link:presentationLink link:calculationLink link:definitionLink 0000035 - 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Disclosure - Equity Incentive Plans - Stock Options (Details) link:presentationLink link:calculationLink link:definitionLink 0000057 - Disclosure - Equity Incentive Plans - Restricted Stock Units (Details) link:presentationLink link:calculationLink link:definitionLink 0000058 - Disclosure - Restructuring (Details) link:presentationLink link:calculationLink link:definitionLink 0000059 - Disclosure - Net Loss Per Share - Computation of Net Loss Per Common Share (Details) link:presentationLink link:calculationLink link:definitionLink 0000060 - Disclosure - Net Loss Per Share - Summary of Anti Dilutive Securities Excluded from Computation of Diluted Net Loss Per Share (Details) link:presentationLink link:calculationLink link:definitionLink 0000061 - Disclosure - Contingencies (Details) link:presentationLink link:calculationLink link:definitionLink 0000062 - Disclosure - Subsequent Events (Details) link:presentationLink link:calculationLink link:definitionLink