Document And Entity Information [Abstract] Document And Entity Information [Abstract] Entity Registrant Name Entity Registrant Name Entity Central Index Key Entity Central Index Key Trading Symbol Trading Symbol Document Type Document Type Document Period End Date Document Period End Date Current Fiscal Year End Date Current Fiscal Year End Date Document Fiscal Year Focus Document Fiscal Year Focus Document Fiscal Period Focus Document Fiscal Period Focus Entity Well-known Seasoned Issuer Entity Well-known Seasoned Issuer Entity Voluntary Filers Entity Voluntary Filers Entity Current Reporting Status Entity Current Reporting Status Amendment Flag Amendment Flag Entity Filer Category Entity Filer Category Entity Common Stock, Shares Outstanding Entity Common Stock, Shares Outstanding Entity Public Float Entity Public Float Consolidated Balance Sheets Assets [Abstract] Assets Assets, Current [Abstract] Current assets: Cash and Cash Equivalents, at Carrying Value Cash and cash equivalents at end of period Cash and cash equivalents at beginning of period Cash and cash equivalents Cash and cash equivalents, Amortized Cost Available-for-sale Securities, Debt Securities, Current Short-term investments Accounts Receivable, Net Accounts receivable Contract with Customer, Asset, Net, Current Unbilled license revenue Prepaid Expense and Other Assets, Current Prepaid expenses and other current assets Assets, Current Current assets Total current assets Property, Plant and Equipment, Net Property and equipment, net Total property and equipment, net Other Assets, Noncurrent Other assets Assets Total assets Liabilities and Equity [Abstract] Liabilities and stockholders' equity Liabilities, Current [Abstract] Current liabilities: Accounts Payable, Current Accounts payable Employee-related Liabilities, Current Accrued compensation and benefits Contract with Customer, Liability, Current Uncharged license fees Accrued Liabilities, Current Accrued and other liabilities Total accrued and other liabilities Liabilities, Current Current liabilities Total current liabilities Loans Payable, Noncurrent Loan payable, long term Loan payable, long term Liabilities, Noncurrent Other long-term liabilities Liabilities Total liabilities Commitments and Contingencies Commitments and contingencies Stockholders' Equity Attributable to Parent [Abstract] Stockholders' equity: Preferred Stock, Value, Issued Preferred stock, $0.0001 par value; 5,000,000 shares authorized; no shares issued and outstanding as of December 31, 2018 and December 31, 2017, respectively. Common Stock, Value, Issued Common stock, $0.0001 par value; 300,000,000 shares authorized; 62,516,627 and 47,534,979 shares issued and outstanding as of December 31, 2018 and December 31, 2017, respectively. Additional Paid in Capital, Common Stock Additional paid-in capital Retained Earnings (Accumulated Deficit) Accumulated deficit Accumulated Other Comprehensive Income (Loss), Net of Tax Accumulated other comprehensive loss Stockholders' Equity Attributable to Parent Balance, amount Balance, amount Total stockholders' equity Liabilities and Equity Total liabilities and stockholders' equity Preferred Stock, Par or Stated Value Per Share Preferred stock, par value Preferred Stock, Shares Authorized Preferred stock, shares authorized Preferred Stock, Shares Issued Preferred stock, shares issued Preferred Stock, Shares Outstanding Preferred stock, shares outstanding Common Stock, Par or Stated Value Per Share Common stock, par value Common Stock, Shares Authorized Common stock, shares authorized Common Stock, Shares, Issued Common stock, shares issued Common stock issued Common Stock, Shares, Outstanding Balance, shares Common stock, shares outstanding Income Statement [Abstract] Statement [Table] Products and Services [Axis] Products And Services [Domain] Products and Services [Domain] Right to use intangible asset. Intangible asset includes, but is not limited to, patent, copyright, technology, manufacturing process, software or trademark. License [Member] Licensing Represents the information pertaining to revenues from other product or services. Other Product Or Services Revenue [Member] Other Statement [Line Items] Revenues [Abstract] Revenues: Revenues Total revenues Cost of Revenue Cost of revenue Gross Profit Gross profit Gross profit Operating Expenses [Abstract] Operating expenses: Research and Development Expense Research and development General and Administrative Expense General and administrative Operating Expenses Operating expenses Total operating expenses Operating Income (Loss) Loss from operations Interest Expense Interest expense Nonoperating Income (Expense) Other income (expense), net Income (Loss) from Continuing Operations before Income Taxes, Noncontrolling Interest Loss before provision for income taxes Income Tax Expense (Benefit) Provision for (benefit from) income taxes Provision for income taxes Net Income (Loss) Attributable to Parent Net income (loss) Net loss Net loss Earnings Per Share, Basic and Diluted Net loss per share - basic and diluted Net loss per share - basic and diluted Net loss per common share, basic and diluted Weighted Average Number of Shares Outstanding, Basic and Diluted Weighted average common shares outstanding - basic and diluted Shares used in computing net loss per share - basic and diluted Comprehensive loss: Other Comprehensive Income (Loss), Available-for-sale Securities Adjustment, Net of Tax, Portion Attributable to Parent Other comprehensive income (loss) Unrealized gain (loss) on available-for-sale securities, net of tax Comprehensive Income (Loss), Net of Tax, Attributable to Parent Comprehensive loss Statement of Stockholders' Equity [Abstract] Equity Components [Axis] Equity Component [Domain] Equity Component [Domain] Common Stock [Member] Common Stock [Member] Additional Paid In Capital [Member] Additional Paid-In Capital [Member] Retained Earnings [Member] Accumulated Deficit [Member] Accumulated Other Comprehensive Income [Member] Other Comprehensive Income (Loss) [Member] Sale of Stock [Axis] Sale Of Stock Name Of Transaction [Domain] Sale of Stock [Domain] Public Offering [Member] Public Offering [Member] Public Offering [Member] Private investment in public equity. Private Investment In Public Equity [Member] Private Investment in Public Equity (PIPE) [Member] Award Type [Axis] Share Based Compensation Arrangements By Share Based Payment Award Award Type And Plan Name [Domain] Equity Award [Domain] Restricted Stock Units R S U [Member] Restricted Stock Units (RSUs) [Member] Stock Issued During Period, Value, New Issues Issuance of common stock, value Shares, Outstanding Balance, shares Stock Issued During Period, Shares, New Issues Common stock sold and issued Issuance of common stock, shares Stock Issued During Period, Value, Employee Stock Purchase Plan Issuance of common stock under employee stock purchase plan, amount Stock Issued During Period, Shares, Employee Stock Purchase Plans Issuance of common stock under employee stock purchase plan, shares Number of shares issued under ESPP Stock Issued During Period, Value, Issued for Services Issuance of common stock for services, amount Stock Issued During Period, Shares, Issued for Services Shares Available for Grant, Issuance of common stock for services Issuance of common stock for services, shares Issuance of common stock for services, shares Stock Issued During Period, Value, Stock Options Exercised Exercise of stock options, amount Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercises in Period Options Issued and Outstanding Number of Shares, Options exercised Exercise of stock options, shares Adjustments to Additional Paid in Capital, Share-based Compensation, Requisite Service Period Recognition Stock-based compensation Cumulative Effect of New Accounting Principle in Period of Adoption Adoption of ASU No. 2014-09 on January 1, 2018 Private Placement [Member] Private Placement [Member] Adjustments to Additional Paid in Capital, Stock Issued, Issuance Costs Stock issuance costs Consolidated Statements of Cash Flows Net Cash Provided by (Used in) Operating Activities, Continuing Operations [Abstract] Operating activities Net Income (Loss), Including Portion Attributable to Noncontrolling Interest Net loss Adjustments to Reconcile Net Income (Loss) to Cash Provided by (Used in) Operating Activities [Abstract] Adjustments to reconcile net loss to net cash used in operating activities: Depreciation Depreciation expense Amortization of Debt Issuance Costs Amortization of deferred financing costs Amount of amortization of deferred compensation expense. Amortization Of Deferred Compensation Expense Amortization of deferred compensation for services Accretion (Amortization) of Discounts and Premiums, Investments Amortization of premium on investment securities Share-based Compensation Stock-based compensation Increase (Decrease) in Derivative Liabilities Change in derivative liabilities Non-cash interest expense. Noncash Interest Expense Non-cash interest associated with debt discount accretion Increase (Decrease) in Operating Capital [Abstract] Changes in operating assets and liabilities: Increase (Decrease) in Accounts Receivable Accounts receivable Increase (Decrease) in Prepaid Expense and Other Assets Prepaid expenses and other assets Increase (Decrease) in Accounts Payable Accounts payable Increase (Decrease) in Employee Related Liabilities Accrued compensation and benefits Increase (Decrease) in Accrued Liabilities Accrued and other liabilities Net Cash Provided by (Used in) Operating Activities, Continuing Operations Net cash used in operating activities Net Cash Provided by (Used in) Investing Activities, Continuing Operations [Abstract] Investing activities Proceeds from Maturities, Prepayments and Calls of Debt Securities, Available-for-sale Proceeds from maturities of investments Proceeds from Sale of Short-term Investments Sales and redemptions of investments Payments to Acquire Short-term Investments Purchases of investments Payments to Acquire Property, Plant, and Equipment Purchases of property and equipment Net Cash Provided by (Used in) Investing Activities, Continuing Operations Net cash (used in) provided by investing activities Net Cash Provided by (Used in) Financing Activities, Continuing Operations [Abstract] Financing activities Proceeds from Debt, Net of Issuance Costs Proceeds from loan payable, net of issuance costs Net proceeds from the loan The cash inflow from the sale of common stock, net of related issuance costs. Proceeds From Issuance Of Common Stock Net Of Issuance Costs Proceeds from issuance of common stock, net of issuance costs Proceeds from Issuance of Shares under Incentive and Share-based Compensation Plans, Including Stock Options Proceeds from issuance of common stock under stock plans Net Cash Provided by (Used in) Financing Activities, Continuing Operations Net cash provided by financing activities Cash and Cash Equivalents, Period Increase (Decrease) Net decrease in cash and cash equivalents Supplemental Cash Flow Information [Abstract] Supplementary disclosure of cash flow information: Income Taxes Paid, Net Income taxes paid Cash Flow, Noncash Investing and Financing Activities Disclosure [Abstract] Supplementary disclosure of non-cash financing information: Represents the non-cash issuance of derivative in connection with issuance of loan payable. Issuance Of Derivative In Connection With Issuance Of Loan Payable Issuance of derivative in connection with issuance of loan payable Capital Expenditures Incurred but Not yet Paid Acquisition of property and equipment included in accounts payable and accrued liabilities Stock Issued Services settled through the issuance of common stock Organization and Basis of Presentation Organization, Consolidation, Basis of Presentation, Business Description and Accounting Policies [Text Block] Organization and Basis of Presentation Summary of Significant Accounting Policies Significant Accounting Policies [Text Block] Summary of Significant Accounting Policies Cash, Cash Equivalents and Investments Cash, Cash Equivalents, and Short-term Investments [Text Block] Cash, Cash Equivalents and Investments Fair Value Measurements Fair Value Disclosures [Text Block] Fair Value Measurements Derivative Financial Instruments Derivative Instruments And Hedging Activities Disclosure [Text Block] Derivative Financial Instruments Borrowings Debt Disclosure [Text Block] Borrowings Shareholders Equity Stockholders' Equity Note Disclosure [Text Block] Shareholders Equity Property and Equipment Property, Plant and Equipment Disclosure [Text Block] Property and Equipment Accrued and Other Liabilities Accounts Payable, Accrued Liabilities, and Other Liabilities Disclosure, Current [Text Block] Accrued and Other Liabilities n/a Collaboration and Licensing Agreements Collaborative Arrangement Disclosure [Text Block] Collaboration and Licensing Agreements Equity Incentive Plans Disclosure of Compensation Related Costs, Share-based Payments [Text Block] Equity Incentive Plans Warrants The entire disclosure for warrants. Warrants [Text Block ] Warrants Income Taxes Income Tax Disclosure [Text Block] Income Taxes Geographic Information and Concentrations The entire disclosure on geographic information and concentrations. Geographic Information And Concentrations [Text Block] Geographic Information and Concentrations Net Loss Per Share Earnings Per Share [Text Block] Net Loss Per Share Commitments and Contingencies. Commitments and Contingencies Disclosure [Text Block] Commitments and Contingencies Selected Quarterly Financial Data (Unaudited) Quarterly Financial Information [Text Block] Selected Quarterly Financial Data (Unaudited) Subsequent Events Subsequent Events [Text Block] Subsequent Events Basis of Accounting, Policy [Policy Text Block] Basis of Presentation Consolidation, Policy [Policy Text Block] Principles of Consolidation Use of Estimates, Policy [Policy Text Block] Use of Estimates Liquidity. Liquidity [Policy Text Block] Liquidity Cash and Cash Equivalents, Policy [Policy Text Block] Cash and Cash Equivalents Short term investments. Short Term Investments [Policy Text Block] Short-Term Investments Concentration Risk, Credit Risk, Policy [Policy Text Block] Concentration of Credit Risk Trade and Other Accounts Receivable, Policy [Policy Text Block] Accounts Receivable Property, Plant and Equipment, Policy [Policy Text Block] Property and Equipment Impairment or Disposal of Long-Lived Assets, Policy [Policy Text Block] Impairment of Long-Lived Assets Income Tax, Policy [Policy Text Block] Income Taxes Research and Development Expense, Policy [Policy Text Block] Research and Development Costs Accrued research and development expenses policy. Accrued Research and Development Expenses Policy [Policy Text Block] Accrued Research and Development Expenses Disclosure of accounting policy for revenue from contract with customer. Revenue From Contract With Customer [Policy Text Block] Revenue Recognition Compensation Related Costs, Policy [Policy Text Block] Stock-Based Compensation Derivatives, Reporting of Derivative Activity [Policy Text Block] Derivatives and Hedging Activities Comprehensive Income, Policy [Policy Text Block] Comprehensive Loss Earnings Per Share, Policy [Policy Text Block] Net Loss per Share