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<div> 1. Organization and Basis of Presentation Ardelyx, Inc. (the “Company”) is a clinical stage biopharmaceutical company focused on the discovery, development and commercialization of innovative, minimally-systemic, small molecule therapeutics that work exclusively in the gastrointestinal tract to treat cardio-renal, gastrointestinal and metabolic diseases. The Company has developed a drug discovery and design platform enabling it, in a rapid and cost-efficient manner, to discover and design novel drug candidates. The Company was incorporated in Delaware on October 17, 2007, under the name Nteryx and changed its name to Ardelyx, Inc. in June 2008. The Company operates in only one business segment, which is the development of biopharmaceutical products. Reverse Stock Split On June 18, 2014, the Company’s Amended and Restated Certificate of Incorporation became effective resulting in a reverse split of the Company’s common stock and convertible preferred stock at a 1-for-9 ratio (the “Reverse Stock Split”). The par value and the authorized shares of the common stock and convertible preferred stock were not adjusted as a result of the Reverse Stock Split. All issued and outstanding common stock, convertible preferred stock, warrants for preferred stock, options for common stock and per share amounts contained in the financial statements have been retroactively adjusted to reflect this Reverse Stock Split for all periods presented. Initial Public Offering On June 18, 2014, the Company’s registration statement on Form S-1 (File No. 333-196090) relating to the initial public offering (the “IPO”) of its common stock was declared effective by the SEC, and the IPO closed on June 24, 2014. The Company sold 4,928,900 shares of its common stock, which included the exercise in full by the underwriters of the IPO of their option to purchase 642,900 additional shares of the Company’s common stock, and the Company received cash proceeds of $61.2 million from the IPO, net of $7.8 million underwriting discounts and commissions and expenses paid by the Company. On June 24, 2014, prior to the closing of the IPO, all outstanding shares of convertible preferred stock converted into 11,517,222 shares of common stock with the related carrying value of $56.2 million being reclassified to common stock and additional paid-in capital. In addition, all convertible preferred stock warrants were net exercised and the related convertible preferred stock warrant liability was reclassified to additional paid-in capital. On June 24, 2014, the Company’s Amended and Restated Certificate of Incorporation became effective and the number of shares of capital stock the Company is authorized to issue was increased to 305,000,000 shares, of which 300,000,000 shares may be common stock and 5,000,000 shares may be preferred stock. Both the common stock and preferred stock have a par value of $0.0001 per share. There are no shares of preferred stock outstanding at December 31, 2014. </div>

<div> 8. Equity Incentive Plans 2008 Plan The Company granted options under its 2008 Stock Incentive Plan (the “2008 Plan”) until June 2014 when it was terminated as to future awards, although it continues to govern the terms of options that remain outstanding under the 2008 Plan. The 2008 Plan provided for the granting of incentive and nonstatutory stock options, and stock purchase rights to employees, directors and consultants at the discretion of the Board of Directors. Stock options granted generally vest over a period of four years from the date of grant. In connection with the Board of Directors and stockholders approval of the 2014 Plan, all remaining shares available for future award under the 2008 Plan were transferred to 2014 Plan, and the 2008 Plan was terminated. 2014 Plan The 2014 Equity Incentive Award Plan (“2014 Plan”) became effective on June 18, 2014, immediately prior to the time the Company’s Registration Statement on Form S-1 became effective. Under the 2014 Plan, 1,419,328 shares of common stock were initially reserved for issuance pursuant to a variety of stock-based compensation awards, including stock options, stock appreciation rights, or SARs, restricted stock awards, restricted stock unit awards, deferred stock awards, deferred stock unit awards, dividend equivalent awards, stock payment awards and performance awards. In addition, 35,221 shares that had been available for future awards under the 2008 Plan as of June 18, 2014, were added to the initial reserve available under the 2014 Plan, bringing the total reserve upon the effective date of the 2014 Plan to 1,454,549. The number of shares initially reserved for issuance or transfer pursuant to awards under the 2014 Plan will be increased by (i) the number of shares represented by awards outstanding under 2008 Plan on June 18, 2014, that are either forfeited or lapse unexercised or that are repurchased for the original purchase price thereof, up to a maximum of 1,153,279 shares, and (ii) if approved by the Administrator of the 2014 Plan, an annual increase on the first day of each fiscal year ending in 2024, equal to the lesser of (A) four percent (4.0%) of the shares of stock outstanding (on an as converted basis) on the last day of the immediately preceding fiscal year and (B) such smaller number of shares of stock as determined by our board of directors; provided, however, that no more than 10,683,053 shares of stock may be issued upon the exercise of incentive stock options.  Effective January 1, 2015, the 2014 Plan share reserve was increased by 743,569 shares. Stock Plan Activity The following table summarizes activity under the 2008 Plan and the 2014 Plan, including grants to nonemployees and restricted stock issued:   <div> <table border="0" cellspacing="0" cellpadding="0" align="center" style="border-collapse:collapse; width:98.3%;"> <tr> <td valign="bottom" style="width:36.46%;">  </td> <td valign="bottom" style="width:0.32%;">  </td> <td colspan="2" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:10.72%;">  </td> <td valign="bottom" style="width:0.46%;">  </td> <td colspan="2" valign="bottom" style="width:0.5%;">  </td> <td colspan="11" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:33.8%; border-bottom:solid 0.75pt #000000;"> <p style="text-align:center;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:bold;font-size:8pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">Options Issued and Outstanding</td> <td colspan="2" valign="bottom" style="width:0.9%;">  </td> <td colspan="3" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:15.12%;">  </td> <td valign="bottom" style="width:1.72%;">  </td> </tr> <tr> <td valign="bottom" style="width:36.46%;">  </td> <td valign="bottom" style="width:0.32%;">  </td> <td colspan="2" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:10.72%; border-bottom:solid 0.75pt #000000;"> <p style="text-align:center;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:bold;font-size:8pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">Shares Available for Grant</td> <td valign="bottom" style="width:0.46%;">  </td> <td colspan="2" valign="bottom" style="width:0.5%;">  </td> <td colspan="3" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:15.06%; border-bottom:solid 0.75pt #000000;"> <p style="text-align:center;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:bold;font-size:8pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">Number of Shares</td> <td colspan="2" valign="bottom" style="width:3.02%;">  </td> <td colspan="2" valign="bottom" style="width:0.52%;">  </td> <td colspan="2" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:14.58%; border-bottom:solid 0.75pt #000000;"> <p style="text-align:center;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:bold;font-size:8pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">Weighted- Average Exercise Price per Share</td> <td colspan="2" valign="bottom" style="width:0.64%;">  </td> <td colspan="2" valign="bottom" style="width:0.9%;">   </td> <td colspan="3" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:15.12%; border-bottom:solid 0.75pt #000000;"> <p style="text-align:center;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:bold;font-size:8pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">Aggregate <p style="text-align:center;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:bold;font-size:8pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">Intrinsic Value</td> <td valign="bottom" style="width:1.72%;">  </td> </tr> <tr> <td valign="bottom" style="width:36.46%;">  </td> <td valign="bottom" style="width:0.32%;">  </td> <td colspan="2" valign="bottom" style="width:10.72%; border-top:solid 0.75pt #000000;">  </td> <td valign="bottom" style="width:0.46%;">  </td> <td colspan="2" valign="bottom" style="width:0.5%;">  </td> <td colspan="3" valign="bottom" style="width:15.06%; border-top:solid 0.75pt #000000;">  </td> <td colspan="2" valign="bottom" style="width:3.02%;">  </td> <td colspan="2" valign="bottom" style="width:0.52%;">  </td> <td colspan="2" valign="bottom" style="width:14.58%; border-top:solid 0.75pt #000000;">  </td> <td colspan="2" valign="bottom" style="width:0.64%;">  </td> <td colspan="2" valign="bottom" style="width:0.9%;">   </td> <td colspan="3" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:15.12%; border-top:solid 0.75pt #000000;"> <p style="text-align:center;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:bold;font-size:8pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">(in thousands)</td> <td valign="bottom" style="width:1.72%;">  </td> </tr> <tr> <td valign="bottom" bgcolor="#CFF0FC" style="width:36.46%;"> Balances at December 31, 2011</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:0.32%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:2.54%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:8.18%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">19,798</td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:0.8%;white-space:nowrap;">  </td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:0.46%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:0.62%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:14.14%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">1,598,513</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:0.8%;white-space:nowrap;">  </td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:2.54%;">  </td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:3.38%;"> $</td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:11.76%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">0.57</td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:0.62%;white-space:nowrap;">  </td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:0.88%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.84%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:12.96%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.72%;">  </td> </tr> <tr> <td valign="bottom" style="width:36.46%;"> Options authorized</td> <td valign="bottom" style="width:0.32%;">  </td> <td valign="bottom" style="width:2.54%;">  </td> <td valign="bottom" style="width:8.18%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">114,428</td> <td colspan="2" valign="bottom" style="width:0.8%;white-space:nowrap;">  </td> <td colspan="2" valign="bottom" style="width:0.46%;">  </td> <td valign="bottom" style="width:0.62%;white-space:nowrap;">  </td> <td valign="bottom" style="width:14.14%;white-space:nowrap;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">—</td> <td valign="bottom" style="width:0.8%;white-space:nowrap;">  </td> <td colspan="2" valign="bottom" style="width:2.54%;">  </td> <td colspan="2" valign="bottom" style="width:3.38%;">  </td> <td colspan="2" valign="bottom" style="width:11.76%;">  </td> <td colspan="2" valign="bottom" style="width:0.62%;">  </td> <td colspan="2" valign="bottom" style="width:0.88%;">  </td> <td valign="bottom" style="width:1.84%;">  </td> <td valign="bottom" style="width:12.96%;">  </td> <td valign="bottom" style="width:1.72%;">  </td> </tr> <tr> <td valign="bottom" bgcolor="#CFF0FC" style="width:36.46%;"> Options granted</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:0.32%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:2.54%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:8.18%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">(81,233</td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:0.8%;white-space:nowrap;"> )</td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:0.46%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:0.62%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:14.14%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">81,233</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:0.8%;white-space:nowrap;">  </td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:2.54%;">  </td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:3.38%;">  </td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:11.76%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">3.46</td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:0.62%;white-space:nowrap;">  </td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:0.88%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.84%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:12.96%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.72%;">  </td> </tr> <tr> <td valign="bottom" style="width:36.46%;"> Options exercised</td> <td valign="bottom" style="width:0.32%;">  </td> <td valign="bottom" style="width:2.54%;white-space:nowrap;">  </td> <td valign="bottom" style="width:8.18%;white-space:nowrap;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">—</td> <td colspan="2" valign="bottom" style="width:0.8%;white-space:nowrap;">  </td> <td colspan="2" valign="bottom" style="width:0.46%;">  </td> <td valign="bottom" style="width:0.62%;">  </td> <td valign="bottom" style="width:14.14%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">(342,131</td> <td valign="bottom" style="width:0.8%;white-space:nowrap;"> )</td> <td colspan="2" valign="bottom" style="width:2.54%;">  </td> <td colspan="2" valign="bottom" style="width:3.38%;">  </td> <td colspan="2" valign="bottom" style="width:11.76%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">0.52</td> <td colspan="2" valign="bottom" style="width:0.62%;white-space:nowrap;">  </td> <td colspan="2" valign="bottom" style="width:0.88%;">  </td> <td valign="bottom" style="width:1.84%;">  </td> <td valign="bottom" style="width:12.96%;">  </td> <td valign="bottom" style="width:1.72%;">  </td> </tr> <tr> <td valign="bottom" bgcolor="#CFF0FC" style="width:36.46%; border-bottom:solid 0.75pt transparent;"> Options canceled</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:0.32%; border-bottom:solid 0.75pt transparent;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:2.54%; border-bottom:solid 0.75pt #000000;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:8.18%; border-bottom:solid 0.75pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">43,848</td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:0.8%; border-bottom:solid 0.75pt transparent;white-space:nowrap;">  </td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:0.46%; border-bottom:solid 0.75pt transparent;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:0.62%; border-bottom:solid 0.75pt #000000;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:14.14%; border-bottom:solid 0.75pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">(43,848</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:0.8%; border-bottom:solid 0.75pt transparent;white-space:nowrap;"> )</td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:2.54%; border-bottom:solid 0.75pt transparent;">  </td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:3.38%; border-bottom:solid 0.75pt transparent;">  </td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:11.76%; border-bottom:solid 0.75pt transparent;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">0.52</td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:0.62%; border-bottom:solid 0.75pt transparent;white-space:nowrap;">  </td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:0.88%; border-bottom:solid 0.75pt transparent;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.84%; border-bottom:solid 0.75pt transparent;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:12.96%; border-bottom:solid 0.75pt transparent;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.72%; border-bottom:solid 0.75pt transparent;">  </td> </tr> <tr> <td valign="bottom" style="width:36.46%;"> Balance at December 31, 2012</td> <td valign="bottom" style="width:0.32%;">  </td> <td valign="bottom" style="width:2.54%; border-top:solid 0.75pt #000000;">  </td> <td valign="bottom" style="width:8.18%; border-top:solid 0.75pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">96,841</td> <td colspan="2" valign="bottom" style="width:0.8%;white-space:nowrap;">  </td> <td colspan="2" valign="bottom" style="width:0.46%;">  </td> <td valign="bottom" style="width:0.62%; border-top:solid 0.75pt #000000;">  </td> <td valign="bottom" style="width:14.14%; border-top:solid 0.75pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">1,293,767</td> <td valign="bottom" style="width:0.8%;white-space:nowrap;">  </td> <td colspan="2" valign="bottom" style="width:2.54%;">  </td> <td colspan="2" valign="bottom" style="width:3.38%;"> $</td> <td colspan="2" valign="bottom" style="width:11.76%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">0.77</td> <td colspan="2" valign="bottom" style="width:0.62%;white-space:nowrap;">  </td> <td colspan="2" valign="bottom" style="width:0.88%;">  </td> <td valign="bottom" style="width:1.84%;">  </td> <td valign="bottom" style="width:12.96%;">  </td> <td valign="bottom" style="width:1.72%;">  </td> </tr> <tr> <td valign="bottom" bgcolor="#CFF0FC" style="width:36.46%;"> Options granted</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:0.32%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:2.54%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:8.18%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">(99,552</td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:0.8%;white-space:nowrap;"> )</td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:0.46%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:0.62%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:14.14%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">99,552</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:0.8%;white-space:nowrap;">  </td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:2.54%;">  </td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:3.38%;">  </td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:11.76%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">3.42</td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:0.62%;white-space:nowrap;">  </td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:0.88%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.84%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:12.96%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.72%;">  </td> </tr> <tr> <td valign="bottom" style="width:36.46%;"> Options exercised</td> <td valign="bottom" style="width:0.32%;">  </td> <td valign="bottom" style="width:2.54%;white-space:nowrap;">  </td> <td valign="bottom" style="width:8.18%;white-space:nowrap;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">—</td> <td colspan="2" valign="bottom" style="width:0.8%;white-space:nowrap;">  </td> <td colspan="2" valign="bottom" style="width:0.46%;">  </td> <td valign="bottom" style="width:0.62%;">  </td> <td valign="bottom" style="width:14.14%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">(223,865</td> <td valign="bottom" style="width:0.8%;white-space:nowrap;"> )</td> <td colspan="2" valign="bottom" style="width:2.54%;">  </td> <td colspan="2" valign="bottom" style="width:3.38%;">  </td> <td colspan="2" valign="bottom" style="width:11.76%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">0.56</td> <td colspan="2" valign="bottom" style="width:0.62%;white-space:nowrap;">  </td> <td colspan="2" valign="bottom" style="width:0.88%;">  </td> <td valign="bottom" style="width:1.84%;">  </td> <td valign="bottom" style="width:12.96%;">  </td> <td valign="bottom" style="width:1.72%;">  </td> </tr> <tr> <td valign="bottom" bgcolor="#CFF0FC" style="width:36.46%; border-bottom:solid 0.75pt transparent;"> Options canceled</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:0.32%; border-bottom:solid 0.75pt transparent;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:2.54%; border-bottom:solid 0.75pt #000000;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:8.18%; border-bottom:solid 0.75pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">6,625</td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:0.8%; border-bottom:solid 0.75pt transparent;white-space:nowrap;">  </td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:0.46%; border-bottom:solid 0.75pt transparent;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:0.62%; border-bottom:solid 0.75pt #000000;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:14.14%; border-bottom:solid 0.75pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">(6,625</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:0.8%; border-bottom:solid 0.75pt transparent;white-space:nowrap;"> )</td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:2.54%; border-bottom:solid 0.75pt transparent;">  </td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:3.38%; border-bottom:solid 0.75pt transparent;">  </td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:11.76%; border-bottom:solid 0.75pt transparent;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">2.23</td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:0.62%; border-bottom:solid 0.75pt transparent;white-space:nowrap;">  </td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:0.88%; border-bottom:solid 0.75pt transparent;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.84%; border-bottom:solid 0.75pt transparent;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:12.96%; border-bottom:solid 0.75pt transparent;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.72%; border-bottom:solid 0.75pt transparent;">  </td> </tr> <tr> <td valign="bottom" style="width:36.46%;"> Balance at December 31, 2013</td> <td valign="bottom" style="width:0.32%;">  </td> <td valign="bottom" style="width:2.54%; border-top:solid 0.75pt #000000;">  </td> <td valign="bottom" style="width:8.18%; border-top:solid 0.75pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">3,914</td> <td colspan="2" valign="bottom" style="width:0.8%;white-space:nowrap;">  </td> <td colspan="2" valign="bottom" style="width:0.46%;">  </td> <td valign="bottom" style="width:0.62%; border-top:solid 0.75pt #000000;">  </td> <td valign="bottom" style="width:14.14%; border-top:solid 0.75pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">1,162,829</td> <td valign="bottom" style="width:0.8%;white-space:nowrap;">  </td> <td colspan="2" valign="bottom" style="width:2.54%;">  </td> <td colspan="2" valign="bottom" style="width:3.38%;"> $</td> <td colspan="2" valign="bottom" style="width:11.76%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">1.03</td> <td colspan="2" valign="bottom" style="width:0.62%;white-space:nowrap;">  </td> <td colspan="2" valign="bottom" style="width:0.88%;">  </td> <td valign="bottom" style="width:1.84%;">  </td> <td valign="bottom" style="width:12.96%;">  </td> <td valign="bottom" style="width:1.72%;white-space:nowrap;">  </td> </tr> <tr> <td valign="bottom" bgcolor="#CFF0FC" style="width:36.46%;"> Options authorized</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:0.32%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:2.54%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:8.18%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">1,452,661</td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:0.8%;white-space:nowrap;">  </td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:0.46%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:0.62%;white-space:nowrap;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:14.14%;white-space:nowrap;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">—</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:0.8%;white-space:nowrap;">  </td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:2.54%;">  </td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:3.38%;">  </td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:11.76%;">  </td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:0.62%;">  </td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:0.88%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.84%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:12.96%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.72%;">  </td> </tr> <tr> <td valign="bottom" style="width:36.46%;"> Options granted</td> <td valign="bottom" style="width:0.32%;">  </td> <td valign="bottom" style="width:2.54%;">  </td> <td valign="bottom" style="width:8.18%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">(188,888</td> <td colspan="2" valign="bottom" style="width:0.8%;white-space:nowrap;"> )</td> <td colspan="2" valign="bottom" style="width:0.46%;">  </td> <td valign="bottom" style="width:0.62%;">  </td> <td valign="bottom" style="width:14.14%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">188,888</td> <td valign="bottom" style="width:0.8%;white-space:nowrap;">  </td> <td colspan="2" valign="bottom" style="width:2.54%;">  </td> <td colspan="2" valign="bottom" style="width:3.38%;">  </td> <td colspan="2" valign="bottom" style="width:11.76%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">24.41</td> <td colspan="2" valign="bottom" style="width:0.62%;white-space:nowrap;">  </td> <td colspan="2" valign="bottom" style="width:0.88%;">  </td> <td valign="bottom" style="width:1.84%;">  </td> <td valign="bottom" style="width:12.96%;">  </td> <td valign="bottom" style="width:1.72%;">  </td> </tr> <tr> <td valign="bottom" bgcolor="#CFF0FC" style="width:36.46%;"> Options exercised</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:0.32%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:2.54%;white-space:nowrap;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:8.18%;white-space:nowrap;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">—</td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:0.8%;white-space:nowrap;">  </td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:0.46%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:0.62%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:14.14%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">(336,398</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:0.8%;white-space:nowrap;"> )</td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:2.54%;">  </td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:3.38%;">  </td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:11.76%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">0.71</td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:0.62%;white-space:nowrap;">  </td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:0.88%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.84%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:12.96%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.72%;">  </td> </tr> <tr> <td valign="bottom" style="width:36.46%;"> Options canceled</td> <td valign="bottom" style="width:0.32%;">  </td> <td valign="bottom" style="width:2.54%;">  </td> <td valign="bottom" style="width:8.18%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">4,084</td> <td colspan="2" valign="bottom" style="width:0.8%;white-space:nowrap;">  </td> <td colspan="2" valign="bottom" style="width:0.46%;">  </td> <td valign="bottom" style="width:0.62%;">  </td> <td valign="bottom" style="width:14.14%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">(4,084</td> <td valign="bottom" style="width:0.8%;white-space:nowrap;"> )</td> <td colspan="2" valign="bottom" style="width:2.54%;">  </td> <td colspan="2" valign="bottom" style="width:3.38%;">  </td> <td colspan="2" valign="bottom" style="width:11.76%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">2.21</td> <td colspan="2" valign="bottom" style="width:0.62%;white-space:nowrap;">  </td> <td colspan="2" valign="bottom" style="width:0.88%;">  </td> <td valign="bottom" style="width:1.84%;">  </td> <td valign="bottom" style="width:12.96%;">  </td> <td valign="bottom" style="width:1.72%;">  </td> </tr> <tr> <td valign="bottom" bgcolor="#CFF0FC" style="width:36.46%;"> Options repurchased</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:0.32%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:2.54%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:8.18%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">3,511</td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:0.8%;white-space:nowrap;">  </td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:0.46%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:0.62%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:14.14%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">(3,511</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:0.8%;white-space:nowrap;"> )</td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:2.54%;">  </td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:3.38%;">  </td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:11.76%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">0.55</td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:0.62%;white-space:nowrap;">  </td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:0.88%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.84%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:12.96%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.72%;">  </td> </tr> <tr> <td valign="bottom" style="width:36.46%; border-bottom:double 2.5pt transparent;"> <p style="margin-bottom:0pt;margin-top:0pt;margin-left:36.35pt;;text-indent:-12pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">Issuance of common stock for services</td> <td valign="bottom" style="width:0.32%; border-bottom:double 2.5pt #000000;">  </td> <td valign="bottom" style="width:2.54%; border-bottom:double 2.5pt #000000;">  </td> <td valign="bottom" style="width:8.18%; border-bottom:double 2.5pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">(10,000</td> <td colspan="2" valign="bottom" style="width:0.8%; border-bottom:double 2.5pt transparent;white-space:nowrap;"> )</td> <td colspan="2" valign="bottom" style="width:0.46%; border-bottom:double 2.5pt transparent;">  </td> <td valign="bottom" style="width:0.62%; border-bottom:double 2.5pt #000000;">  </td> <td valign="bottom" style="width:14.14%; border-bottom:double 2.5pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">—</td> <td valign="bottom" style="width:0.8%; border-bottom:double 2.5pt transparent;white-space:nowrap;">  </td> <td colspan="2" valign="bottom" style="width:2.54%; border-bottom:double 2.5pt transparent;">  </td> <td colspan="2" valign="bottom" style="width:3.38%; border-bottom:double 2.5pt transparent;">  </td> <td colspan="2" valign="bottom" style="width:11.76%; border-bottom:double 2.5pt transparent;"> <p style="text-align:right;margin-top:0pt;margin-bottom:0pt;margin-left:0pt;;text-indent:0pt;;font-size:8pt;font-weight:normal;font-style:normal;font-family:Times New Roman;text-transform:none;font-variant: normal;">—</td> <td colspan="2" valign="bottom" style="width:0.62%; border-bottom:double 2.5pt transparent;">  </td> <td colspan="2" valign="bottom" style="width:0.88%; border-bottom:double 2.5pt transparent;">  </td> <td valign="bottom" style="width:1.84%; border-bottom:double 2.5pt transparent;">  </td> <td valign="bottom" style="width:12.96%; border-bottom:double 2.5pt transparent;">  </td> <td valign="bottom" style="width:1.72%; border-bottom:double 2.5pt transparent;">  </td> </tr> <tr> <td valign="bottom" bgcolor="#CFF0FC" style="width:36.46%; border-bottom:double 2.5pt transparent;"> Balance at December 31, 2014</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:0.32%; border-top:double 2.5pt #000000; border-bottom:double 2.5pt transparent;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:2.54%; border-top:double 2.5pt #000000; border-bottom:double 2.5pt #000000;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:8.18%; border-top:solid 0.75pt #000000; border-bottom:double 2.5pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">1,265,282</td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:0.8%; border-bottom:double 2.5pt transparent;white-space:nowrap;">  </td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:0.46%; border-bottom:double 2.5pt transparent;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:0.62%; border-top:solid 0.75pt #000000; border-bottom:double 2.5pt #000000;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:14.14%; border-top:solid 0.75pt #000000; border-bottom:double 2.5pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">1,007,724</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:0.8%; border-bottom:double 2.5pt transparent;white-space:nowrap;">  </td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:2.54%; border-bottom:double 2.5pt transparent;">  </td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:3.38%; border-bottom:double 2.5pt transparent;"> $</td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:11.76%; border-bottom:double 2.5pt transparent;"> <p style="text-align:right;margin-top:0pt;margin-bottom:0pt;margin-left:0pt;;text-indent:0pt;;font-size:10pt;font-weight:normal;font-style:normal;font-family:Times New Roman;text-transform:none;font-variant: normal;">5.51</td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:0.62%; border-bottom:double 2.5pt transparent;">  </td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:0.88%; border-bottom:double 2.5pt transparent;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.84%; border-bottom:double 2.5pt transparent;"> $</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:12.96%; border-bottom:double 2.5pt transparent;"> <p style="text-align:right;margin-top:0pt;margin-bottom:0pt;margin-left:0pt;;text-indent:0pt;;font-size:10pt;font-weight:normal;font-style:normal;font-family:Times New Roman;text-transform:none;font-variant: normal;">14,839</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.72%; border-bottom:double 2.5pt transparent;">  </td> </tr> <tr> <td valign="bottom" style="width:36.46%; border-bottom:double 2.5pt transparent;"> Vested and expected to vest at December 31, 2014</td> <td valign="bottom" style="width:0.32%; border-bottom:double 2.5pt transparent;">  </td> <td valign="bottom" style="width:2.54%; border-top:double 2.5pt #000000; border-bottom:double 2.5pt transparent;">  </td> <td valign="bottom" style="width:8.18%; border-top:double 2.5pt #000000; border-bottom:double 2.5pt transparent;">  </td> <td colspan="2" valign="bottom" style="width:0.8%; border-bottom:double 2.5pt transparent;">  </td> <td colspan="2" valign="bottom" style="width:0.46%; border-bottom:double 2.5pt transparent;">  </td> <td valign="bottom" style="width:0.62%; border-top:double 2.5pt #000000; border-bottom:double 2.5pt #000000;"> <p style="margin-top:0pt;padding-top:1pt;text-align:center;border-top:nil 0pt;margin-bottom:0pt;margin-left:0pt;;text-indent:0pt;;font-size:10pt;font-family:Times New Roman;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;"> </td> <td valign="bottom" style="width:14.14%; border-top:double 2.5pt #000000; border-bottom:double 2.5pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">990,889</td> <td valign="bottom" style="width:0.8%; border-bottom:double 2.5pt transparent;">  </td> <td colspan="2" valign="bottom" style="width:2.54%; border-bottom:double 2.5pt transparent;">  </td> <td colspan="2" valign="bottom" style="width:3.38%; border-bottom:double 2.5pt transparent;"> $</td> <td colspan="2" valign="bottom" style="width:11.76%; border-bottom:double 2.5pt transparent;"> <p style="text-align:right;margin-top:0pt;margin-bottom:0pt;margin-left:0pt;;text-indent:0pt;;font-size:10pt;font-weight:normal;font-style:normal;font-family:Times New Roman;text-transform:none;font-variant: normal;">5.27</td> <td colspan="2" valign="bottom" style="width:0.62%; border-bottom:double 2.5pt transparent;">  </td> <td colspan="2" valign="bottom" style="width:0.88%; border-bottom:double 2.5pt transparent;">  </td> <td valign="bottom" style="width:1.84%; border-bottom:double 2.5pt transparent;"> $</td> <td valign="bottom" style="width:12.96%; border-bottom:double 2.5pt transparent;"> <p style="text-align:right;margin-top:0pt;margin-bottom:0pt;margin-left:0pt;;text-indent:0pt;;font-size:10pt;font-weight:normal;font-style:normal;font-family:Times New Roman;text-transform:none;font-variant: normal;">14,746</td> <td valign="bottom" style="width:1.72%; border-bottom:double 2.5pt transparent;">  </td> </tr> <tr> <td valign="bottom" bgcolor="#CFF0FC" style="width:36.46%; border-bottom:double 2.5pt transparent;"> Vested at December 31, 2014</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:0.32%; border-bottom:double 2.5pt transparent;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:2.54%; border-bottom:double 2.5pt transparent;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:8.18%; border-bottom:double 2.5pt transparent;">  </td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:0.8%; border-bottom:double 2.5pt transparent;">  </td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:0.46%; border-bottom:double 2.5pt transparent;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:0.62%; border-top:double 2.5pt #000000; border-bottom:double 2.5pt #000000;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:14.14%; border-top:double 2.5pt #000000; border-bottom:double 2.5pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">643,217</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:0.8%; border-bottom:double 2.5pt transparent;white-space:nowrap;">  </td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:2.54%; border-bottom:double 2.5pt transparent;">  </td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:3.38%; border-bottom:double 2.5pt transparent;"> $</td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:11.76%; border-bottom:double 2.5pt transparent;"> <p style="text-align:right;margin-top:0pt;margin-bottom:0pt;margin-left:0pt;;text-indent:0pt;;font-size:10pt;font-weight:normal;font-style:normal;font-family:Times New Roman;text-transform:none;font-variant: normal;">1.21</td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:0.62%; border-bottom:double 2.5pt transparent;">  </td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:0.88%; border-bottom:double 2.5pt transparent;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.84%; border-bottom:double 2.5pt transparent;"> $</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:12.96%; border-bottom:double 2.5pt transparent;"> <p style="text-align:right;margin-top:0pt;margin-bottom:0pt;margin-left:0pt;;text-indent:0pt;;font-size:10pt;font-weight:normal;font-style:normal;font-family:Times New Roman;text-transform:none;font-variant: normal;">11,376</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.72%; border-bottom:double 2.5pt transparent;">  </td> </tr> </table></div> The weighted-average grant-date estimated fair value of options granted during the years ended December 31, 2014, 2013 and 2012 was $18.53, $2.68 and $2.56 per share. The aggregate intrinsic value was calculated as the difference between the exercise price of the options and the estimated fair value of the Company’s common stock of $18.89 per share as of December 31, 2014. 2014 Employee Stock Purchase Plan The Company adopted the 2014 Employee Stock Purchase Plan (ESPP) and initially reserved 202,762 shares of common stock as of its effective date of June 18, 2014. If approved by the Administrator of the ESPP, on the first day of each calendar year, ending in 2024, the number of shares in the reserve will increase by an amount equal to the lesser of (i) one percent (1.0%) of the shares of common stock outstanding on the last day of the immediately preceding fiscal year and (ii) such number of shares of common stock as determined by the board of directors; provided, however, no more than 2,230,374 shares of our common stock may be issued under the ESPP. Effective January 1, 2015, the ESPP share reserve was increased by 185,892. Under the ESPP, participants are offered the option to purchase shares of the Company’s common stock at a discount during a series of successive offering periods normally commencing on March 1 and September 1 of each year. The initial offering period commenced on September 1, 2014 and will end on February 27, 2015. <p style="Background-color:#FFFFFF;margin-top:12pt;margin-bottom:0pt;text-indent:4.54%;color:#;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">As of December 31, 2014, no shares of common stock have been issued to employees participating in the ESPP and 202,762 shares were available for issuance under the ESPP. The following table illustrates the weighted-average assumptions for the Black-Scholes option-pricing model used in determining the fair value of ESPP purchase rights granted to employees: <div> <table border="0" cellspacing="0" cellpadding="0" align="center" style="border-collapse:collapse; width:55.52%;"> <tr> <td valign="bottom" style="width:73.86%;">  </td> <td valign="bottom" style="width:1.02%;">  </td> <td colspan="4" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:23.34%;"> <p style="text-align:center;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:bold;font-size:8pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">Year Ended December 31, 2014</td> </tr> <tr> <td valign="bottom" bgcolor="#CFF0FC" style="width:73.86%;"> Expected term (years)</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.02%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.04%; border-top:solid 0.75pt #000000;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:17.88%; border-top:solid 0.75pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">0.5</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:3.02%; border-top:solid 0.75pt #000000;white-space:nowrap;">  </td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:1.5%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.68%;">  </td> </tr> <tr> <td valign="bottom" style="width:73.86%;"> Volatility</td> <td valign="bottom" style="width:1.02%;">  </td> <td valign="bottom" style="width:1.04%;">  </td> <td valign="bottom" style="width:17.88%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">73</td> <td valign="bottom" style="width:3.02%;white-space:nowrap;"> %</td> <td colspan="2" valign="bottom" style="width:1.5%;">  </td> <td valign="bottom" style="width:1.68%;">  </td> </tr> <tr> <td valign="bottom" bgcolor="#CFF0FC" style="width:73.86%;"> Risk-free interest rate</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.02%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.04%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:17.88%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">0.05</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:3.02%;white-space:nowrap;"> %</td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:1.5%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.68%;">  </td> </tr> <tr style="height:3.35pt;"> <td valign="bottom" style="width:73.86%;"> Dividend yield</td> <td valign="bottom" style="width:1.02%;">  </td> <td valign="bottom" style="width:1.04%;">  </td> <td valign="bottom" style="width:17.88%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">—</td> <td valign="bottom" style="width:3.02%;white-space:nowrap;"> %</td> <td colspan="2" valign="bottom" style="width:1.5%;">  </td> <td valign="bottom" style="width:1.68%;">  </td> </tr> </table></div> Liability for Early Exercise of Stock Options As of December 31, 2014 and 2013, there were zero and 286,217 shares of common stock outstanding, respectively, subject to the Company’s right of repurchase at prices ranging from $0.27 to $1.08 per share. As of December 31, 2014 and 2013, the Company recorded zero and $0.2 million, respectively, as liabilities associated with shares issued with repurchase rights. Modification of Stock Awards During September 2014, the Company entered into a Transition and Separation Agreement with its Chief Scientific Officer, Dominique Charmot, under which certain restricted shares that were subject to vesting and repurchase by the Company have become fully vested as of Dr. Charmot’s separation from the Company as an employee and director on December 23, 2014. This resulted in the acceleration of the vesting for 58,969 shares of restricted stock. As a result of the acceleration, the Company has recorded a stock-based compensation charge of $0.8 million during the year ended December 31, 2014 to reflect the revised service period for the restricted stock and related vesting of shares that would otherwise not have vested. Stock-based Compensation Total stock-based compensation recognized was as follows (in thousands):   <div> <table border="0" cellspacing="0" cellpadding="0" align="center" style="border-collapse:collapse; width:80%;"> <tr> <td valign="bottom" style="width:51.84%;">  </td> <td valign="bottom" style="width:1.22%;">  </td> <td colspan="10" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:45.7%; border-bottom:solid 1pt #000000;"> <p style="text-align:center;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:bold;font-size:8pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">Year Ended December 31,</td> <td valign="bottom" style="width:1.24%;">  </td> </tr> <tr> <td valign="bottom" style="width:51.84%;">  </td> <td valign="bottom" style="width:1.22%;">  </td> <td colspan="2" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:13.58%; border-bottom:solid 0.75pt #000000;"> <p style="text-align:center;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:bold;font-size:8pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">2014</td> <td valign="bottom" style="width:1.24%;">  </td> <td valign="bottom" style="width:1.24%;">   </td> <td colspan="2" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:13.58%; border-bottom:solid 0.75pt #000000;"> <p style="text-align:center;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:bold;font-size:8pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">2013</td> <td valign="bottom" style="width:1.24%;">  </td> <td valign="bottom" style="width:1.24%;">   </td> <td colspan="2" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:13.58%; border-bottom:solid 0.75pt #000000;"> <p style="text-align:center;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:bold;font-size:8pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">2012</td> <td valign="bottom" style="width:1.24%;">  </td> </tr> <tr> <td valign="bottom" style="width:51.84%;">  </td> <td valign="bottom" style="width:1.22%;">  </td> <td colspan="2" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:13.58%;">  </td> <td valign="bottom" style="width:1.24%;">  </td> <td valign="bottom" style="width:1.24%;">  </td> <td colspan="2" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:13.58%;"> <p style="text-align:center;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:bold;font-size:8pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">(in thousands)</td> <td valign="bottom" style="width:1.24%;">  </td> <td valign="bottom" style="width:1.24%;">  </td> <td colspan="2" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:13.58%;">  </td> <td valign="bottom" style="width:1.24%;">  </td> </tr> <tr> <td valign="bottom" bgcolor="#CFF0FC" style="width:51.84%;"> Research and development</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.22%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.24%;"> $</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:12.34%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">1,376</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.24%;white-space:nowrap;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.24%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.24%;"> $</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:12.34%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">200</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.24%;white-space:nowrap;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.24%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.24%;"> $</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:12.34%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">221</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.24%;white-space:nowrap;">  </td> </tr> <tr> <td valign="bottom" style="width:51.84%; border-bottom:solid 0.75pt transparent;"> General and administrative</td> <td valign="bottom" style="width:1.22%; border-bottom:solid 0.75pt transparent;">  </td> <td valign="bottom" style="width:1.24%; border-bottom:solid 0.75pt #000000;">  </td> <td valign="bottom" style="width:12.34%; border-bottom:solid 0.75pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">316</td> <td valign="bottom" style="width:1.24%; border-bottom:solid 0.75pt transparent;white-space:nowrap;">  </td> <td valign="bottom" style="width:1.24%; border-bottom:solid 0.75pt transparent;">  </td> <td valign="bottom" style="width:1.24%; border-bottom:solid 0.75pt #000000;">  </td> <td valign="bottom" style="width:12.34%; border-bottom:solid 0.75pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">152</td> <td valign="bottom" style="width:1.24%; border-bottom:solid 0.75pt transparent;white-space:nowrap;">  </td> <td valign="bottom" style="width:1.24%; border-bottom:solid 0.75pt transparent;">  </td> <td valign="bottom" style="width:1.24%; border-bottom:solid 0.75pt #000000;">  </td> <td valign="bottom" style="width:12.34%; border-bottom:solid 0.75pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">252</td> <td valign="bottom" style="width:1.24%; border-bottom:solid 0.75pt transparent;white-space:nowrap;">  </td> </tr> <tr> <td valign="bottom" bgcolor="#CFF0FC" style="width:51.84%; border-bottom:double 2.5pt transparent;"> Total stock-based compensation</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.22%; border-bottom:double 2.5pt transparent;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.24%; border-top:solid 0.75pt #000000; border-bottom:double 2.5pt #000000;"> $</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:12.34%; border-top:solid 0.75pt #000000; border-bottom:double 2.5pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">1,692</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.24%; border-bottom:double 2.5pt transparent;white-space:nowrap;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.24%; border-bottom:double 2.5pt transparent;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.24%; border-top:solid 0.75pt #000000; border-bottom:double 2.5pt #000000;"> $</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:12.34%; border-top:solid 0.75pt #000000; border-bottom:double 2.5pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">352</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.24%; border-bottom:double 2.5pt transparent;white-space:nowrap;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.24%; border-bottom:double 2.5pt transparent;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.24%; border-top:solid 0.75pt #000000; border-bottom:double 2.5pt #000000;"> $</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:12.34%; border-top:solid 0.75pt #000000; border-bottom:double 2.5pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">473</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.24%; border-bottom:double 2.5pt transparent;white-space:nowrap;">  </td> </tr> </table></div> As of December 31, 2014, there was $3.2 million of unrecognized stock-based compensation expense, net of estimated forfeitures, related to unvested share options with a weighted-average remaining recognition period of 2.3 years. In determining the fair value of the stock-based awards, the Company uses the Black-Scholes option-pricing model and assumptions discussed below. Each of these inputs is subjective and generally requires significant judgment to determine. Expected Term— The Company’s expected term represents the period that the Company’s stock-based awards are expected to be outstanding. The Company used the simplified method to determine the expected term, which is calculated as the average of the time-to-vesting and the contractual life of the options. Expected Volatility— The Company was privately held prior to its IPO in June 2014 and thus a sufficient trading history does not exist for the Company’s common stock. The expected volatility was estimated based on the average volatility for comparable publicly traded biopharmaceutical companies over a period equal to the expected term of the stock option grants. When selecting comparable publicly traded biopharmaceutical companies on which it has based its expected stock price volatility, the Company selected companies with comparable characteristics to it, including enterprise value, risk profiles, position within the industry, and with historical share price information sufficient to meet the expected life of the stock-based awards. The historical volatility data was computed using the daily closing prices for the selected companies’ shares during the equivalent period of the calculated expected term of the stock-based awards. The Company will continue to apply this process until a sufficient amount of historical information regarding the volatility of its own stock price becomes available. Risk-Free Interest Rate— The risk-free interest rate is based on the U.S. Treasury zero coupon issues in effect at the time of grant for periods corresponding with the expected term of option. Expected Dividend— The Company has never paid dividends on its common stock and has no plans to pay dividends on its common stock. Therefore, the Company used an expected dividend yield of zero. The fair value of stock option awards to employees was estimated at the date of grant using a Black-Scholes option-pricing model with the following weighted-average assumptions:   <div> <table border="0" cellspacing="0" cellpadding="0" align="center" style="border-collapse:collapse; width:80%;"> <tr> <td valign="bottom" style="width:42%;">  </td> <td valign="bottom" style="width:1%;">  </td> <td colspan="10" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:1%; border-bottom:solid 1pt #000000;"> <p style="text-align:center;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:bold;font-size:8pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">Year Ended December 31</td> <td valign="bottom" style="width:1%;">  </td> </tr> <tr> <td valign="bottom" style="width:42%;">  </td> <td valign="bottom" style="width:1%;">  </td> <td colspan="2" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:1%; border-bottom:solid 1pt #000000;"> <p style="text-align:center;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:bold;font-size:8pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">2014</td> <td valign="bottom" style="width:1%;">  </td> <td valign="bottom" style="width:1%;">  </td> <td colspan="2" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:1%; border-bottom:solid 1pt #000000;"> <p style="text-align:center;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:bold;font-size:8pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">2013</td> <td valign="bottom" style="width:1%;">  </td> <td valign="bottom" style="width:1%;">  </td> <td colspan="2" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:1%; border-bottom:solid 1pt #000000;"> <p style="text-align:center;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:bold;font-size:8pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">2012</td> <td valign="bottom" style="width:1%;">  </td> </tr> <tr> <td valign="bottom" bgcolor="#CFF0FC" style="width:42%;"> Expected term (years)</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:10%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">5.97</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;white-space:nowrap;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:10%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">6.07</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;white-space:nowrap;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:10%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">5.73</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;white-space:nowrap;">  </td> </tr> <tr> <td valign="bottom" style="width:42%;"> Volatility</td> <td valign="bottom" style="width:1%;">  </td> <td valign="bottom" style="width:1%;">  </td> <td valign="bottom" style="width:10%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">94</td> <td valign="bottom" style="width:1%;white-space:nowrap;"> %</td> <td valign="bottom" style="width:1%;">  </td> <td valign="bottom" style="width:1%;">  </td> <td valign="bottom" style="width:10%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">98</td> <td valign="bottom" style="width:1%;white-space:nowrap;"> %</td> <td valign="bottom" style="width:1%;">  </td> <td valign="bottom" style="width:1%;">  </td> <td valign="bottom" style="width:10%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">97</td> <td valign="bottom" style="width:1%;white-space:nowrap;"> %</td> </tr> <tr> <td valign="bottom" bgcolor="#CFF0FC" style="width:42%;"> Risk-free interest rate</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:10%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">1.79</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;white-space:nowrap;"> %</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:10%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">1.35</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;white-space:nowrap;"> %</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:10%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">0.79</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;white-space:nowrap;"> %</td> </tr> <tr style="height:3.35pt;"> <td valign="bottom" style="width:42%;"> Dividend yield</td> <td valign="bottom" style="width:1%;">  </td> <td valign="bottom" style="width:1%;">  </td> <td valign="bottom" style="width:10%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">—</td> <td valign="bottom" style="width:1%;white-space:nowrap;"> %</td> <td valign="bottom" style="width:1%;">  </td> <td valign="bottom" style="width:1%;">  </td> <td valign="bottom" style="width:10%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">—</td> <td valign="bottom" style="width:1%;white-space:nowrap;"> %</td> <td valign="bottom" style="width:1%;">  </td> <td valign="bottom" style="width:1%;">  </td> <td valign="bottom" style="width:10%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">—</td> <td valign="bottom" style="width:1%;white-space:nowrap;"> %</td> </tr> </table></div> The weighted-average, estimated grant-date fair value of employee stock options granted during the years ended December 31, 2014, 2013 and 2012 was $18.57, $2.68 and $2.56 per share, respectively.   Options Granted to Nonemployees The Company has granted options to purchase shares of common stock to consultants in exchange for services performed. The Company granted options to purchase 10,000 and 3,333 shares with average exercise prices of $20.77 and $3.43 per share, respectively, during the years ended December 31, 2014 and 2013, respectively. These options vest upon grant or various terms up to three years. The Company recognized non-employees stock compensation expense of $0.1 million, $2,000 and zero during the years ended December 31, 2014, 2013 and 2012, respectively. The fair value of non-employees’ options was measured using the Black-Scholes option-pricing model reflecting the same assumptions as applied to employee options in each of the reported years, other than the expected life, which is assumed to be the remaining contractual life of the option.   Issuance of Common Stock for Services During the year ended December 31, 2014, the Company issued 10,000 shares of common stock to consultants in exchange for services performed.  The shares issued were valued at $0.2 million based on the fair value of the common stock on the date of grant.    </div>

<div>   9. Income Taxes The following is a reconciliation of the statutory federal income tax rate to the Company’s effective tax rate:   <div> <table border="0" cellspacing="0" cellpadding="0" align="center" style="border-collapse:collapse; width:80%;"> <tr> <td valign="bottom" style="width:42%;">  </td> <td valign="bottom" style="width:1%;">  </td> <td colspan="10" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:1%; border-bottom:solid 1pt #000000;"> <p style="text-align:center;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:bold;font-size:8pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">Year Ended December 31,</td> <td valign="bottom" style="width:1%;">  </td> </tr> <tr> <td valign="bottom" style="width:42%;">  </td> <td valign="bottom" style="width:1%;">  </td> <td colspan="2" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:1%; border-bottom:solid 1pt #000000;"> <p style="text-align:center;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:bold;font-size:8pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">2014</td> <td valign="bottom" style="width:1%;">  </td> <td valign="bottom" style="width:1%;">  </td> <td colspan="2" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:1%; border-bottom:solid 1pt #000000;"> <p style="text-align:center;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:bold;font-size:8pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">2013</td> <td valign="bottom" style="width:1%;">  </td> <td valign="bottom" style="width:1%;">  </td> <td colspan="2" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:1%; border-bottom:solid 1pt #000000;"> <p style="text-align:center;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:bold;font-size:8pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">2012</td> <td valign="bottom" style="width:1%;">  </td> </tr> <tr> <td valign="bottom" bgcolor="#CFF0FC" style="width:42%;"> Expected income tax provision at the federal statutory rate</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:10%;"> <p style="margin-top:0pt;text-align:right;margin-bottom:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">35.0</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;white-space:nowrap;"> <p style="text-align:left;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:normal;font-style:normal;font-family:Times New Roman;font-size:10pt;text-transform:none;font-variant: normal;">%</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:10%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">35.0</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;white-space:nowrap;"> %</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:10%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">35.0</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;white-space:nowrap;"> %</td> </tr> <tr> <td valign="bottom" style="width:42%;"> State taxes, net of federal benefit</td> <td valign="bottom" style="width:1%;">  </td> <td valign="bottom" style="width:1%;">  </td> <td valign="bottom" style="width:10%;"> <p style="margin-top:0pt;text-align:right;margin-bottom:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">4.6</td> <td valign="bottom" style="width:1%;white-space:nowrap;">  </td> <td valign="bottom" style="width:1%;">  </td> <td valign="bottom" style="width:1%;">  </td> <td valign="bottom" style="width:10%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">(1.4</td> <td valign="bottom" style="width:1%;white-space:nowrap;"> )</td> <td valign="bottom" style="width:1%;">  </td> <td valign="bottom" style="width:1%;">  </td> <td valign="bottom" style="width:10%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">—</td> <td valign="bottom" style="width:1%;white-space:nowrap;">  </td> </tr> <tr> <td valign="bottom" bgcolor="#CFF0FC" style="width:42%;"> Change in valuation allowance</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:10%;"> <p style="margin-top:0pt;text-align:right;margin-bottom:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">(17.9</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;white-space:nowrap;"> )</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:10%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">(22.6</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;white-space:nowrap;"> )</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:10%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">(38.6</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;white-space:nowrap;"> )</td> </tr> <tr> <td valign="bottom" style="width:42%;"> Nondeductible expenses</td> <td valign="bottom" style="width:1%;">  </td> <td valign="bottom" style="width:1%;">  </td> <td valign="bottom" style="width:10%;"> <p style="margin-top:0pt;text-align:right;margin-bottom:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">(20.6</td> <td valign="bottom" style="width:1%;white-space:nowrap;"> <p style="text-align:left;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:normal;font-style:normal;font-family:Times New Roman;font-size:10pt;text-transform:none;font-variant: normal;">)</td> <td valign="bottom" style="width:1%;">  </td> <td valign="bottom" style="width:1%;">  </td> <td valign="bottom" style="width:10%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">(20.8</td> <td valign="bottom" style="width:1%;white-space:nowrap;"> )</td> <td valign="bottom" style="width:1%;">  </td> <td valign="bottom" style="width:1%;">  </td> <td valign="bottom" style="width:10%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">(5.2</td> <td valign="bottom" style="width:1%;white-space:nowrap;"> )</td> </tr> <tr> <td valign="bottom" bgcolor="#CFF0FC" style="width:42%;"> Tax credits</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:10%;"> <p style="margin-top:0pt;text-align:right;margin-bottom:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">—</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;white-space:nowrap;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:10%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">7.3</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;white-space:nowrap;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:10%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">4.4</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;white-space:nowrap;">  </td> </tr> <tr> <td valign="bottom" style="width:42%; border-bottom:solid 0.75pt transparent;"> Other</td> <td valign="bottom" style="width:1%; border-bottom:solid 0.75pt transparent;">  </td> <td valign="bottom" style="width:1%; border-bottom:solid 0.75pt #000000;">  </td> <td valign="bottom" style="width:10%; border-bottom:solid 0.75pt #000000;"> <p style="margin-top:0pt;text-align:right;margin-bottom:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">(3.2</td> <td valign="bottom" style="width:1%; border-bottom:solid 0.75pt transparent;white-space:nowrap;"> <p style="text-align:left;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:normal;font-style:normal;font-family:Times New Roman;font-size:10pt;text-transform:none;font-variant: normal;">)</td> <td valign="bottom" style="width:1%; border-bottom:solid 0.75pt transparent;">  </td> <td valign="bottom" style="width:1%; border-bottom:solid 0.75pt #000000;">  </td> <td valign="bottom" style="width:10%; border-bottom:solid 0.75pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">0.3</td> <td valign="bottom" style="width:1%; border-bottom:solid 0.75pt transparent;white-space:nowrap;">  </td> <td valign="bottom" style="width:1%; border-bottom:solid 0.75pt transparent;">  </td> <td valign="bottom" style="width:1%; border-bottom:solid 0.75pt #000000;">  </td> <td valign="bottom" style="width:10%; border-bottom:solid 0.75pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">4.4</td> <td valign="bottom" style="width:1%; border-bottom:solid 0.75pt transparent;white-space:nowrap;">  </td> </tr> <tr> <td valign="bottom" bgcolor="#CFF0FC" style="width:42%; border-bottom:double 2.5pt transparent;"> Income tax provision</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%; border-bottom:double 2.5pt transparent;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%; border-top:solid 0.75pt #000000; border-bottom:double 2.5pt #000000;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:10%; border-top:solid 0.75pt #000000; border-bottom:double 2.5pt #000000;"> <p style="margin-top:0pt;text-align:right;margin-bottom:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">(2.1</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%; border-bottom:double 2.5pt transparent;white-space:nowrap;"> )%</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%; border-bottom:double 2.5pt transparent;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%; border-top:solid 0.75pt #000000; border-bottom:double 2.5pt #000000;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:10%; border-top:solid 0.75pt #000000; border-bottom:double 2.5pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">(2.2</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%; border-bottom:double 2.5pt transparent;white-space:nowrap;"> )%</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%; border-bottom:double 2.5pt transparent;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%; border-top:solid 0.75pt #000000; border-bottom:double 2.5pt #000000;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:10%; border-top:solid 0.75pt #000000; border-bottom:double 2.5pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">—</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%; border-bottom:double 2.5pt transparent;white-space:nowrap;"> %</td> </tr> </table></div> Significant components of the Company’s deferred tax assets are as follows:   <div> <table border="0" cellspacing="0" cellpadding="0" align="center" style="border-collapse:collapse; width:70%;"> <tr> <td valign="bottom" style="width:63.4%;">  </td> <td valign="bottom" style="width:1.42%;">  </td> <td colspan="6" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:33.8%; border-bottom:solid 1pt #000000;"> <p style="text-align:center;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:bold;font-size:8pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">December 31,</td> <td valign="bottom" style="width:1.4%;">  </td> </tr> <tr> <td valign="bottom" style="width:63.4%;">  </td> <td valign="bottom" style="width:1.42%;">  </td> <td colspan="2" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:15.5%; border-bottom:solid 0.75pt #000000;"> <p style="text-align:center;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:bold;font-size:8pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">2014</td> <td valign="bottom" style="width:1.4%;">  </td> <td valign="bottom" style="width:1.4%;">   </td> <td colspan="2" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:15.48%; border-bottom:solid 0.75pt #000000;"> <p style="text-align:center;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:bold;font-size:8pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">2013</td> <td valign="bottom" style="width:1.4%;">  </td> </tr> <tr> <td valign="bottom" style="width:63.4%;">  </td> <td valign="bottom" style="width:1.42%;">  </td> <td colspan="2" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:15.5%;">  </td> <td valign="bottom" style="width:1.4%;">  </td> <td valign="bottom" style="width:1.4%;">  </td> <td colspan="2" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:15.48%;">  </td> <td valign="bottom" style="width:1.4%;">  </td> </tr> <tr> <td valign="bottom" style="width:63.4%;">  </td> <td valign="bottom" style="width:1.42%;">  </td> <td colspan="6" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:33.8%;"> <p style="text-align:center;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:bold;font-size:8pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">(in thousands)</td> <td valign="bottom" style="width:1.4%;">  </td> </tr> <tr> <td valign="bottom" bgcolor="#CFF0FC" style="width:63.4%;"> Deferred tax assets:</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.42%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.42%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:14.1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.4%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.4%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.4%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:14.08%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.4%;">  </td> </tr> <tr> <td valign="bottom" style="width:63.4%;"> Net operating loss carryforwards</td> <td valign="bottom" style="width:1.42%;">  </td> <td valign="bottom" style="width:1.42%;"> $</td> <td valign="bottom" style="width:14.1%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">11,262</td> <td valign="bottom" style="width:1.4%;white-space:nowrap;">  </td> <td valign="bottom" style="width:1.4%;">  </td> <td valign="bottom" style="width:1.4%;"> $</td> <td valign="bottom" style="width:14.08%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">13,069</td> <td valign="bottom" style="width:1.4%;white-space:nowrap;">  </td> </tr> <tr> <td valign="bottom" bgcolor="#CFF0FC" style="width:63.4%;"> Deferred revenue</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.42%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.42%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:14.1%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">11,099</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.4%;white-space:nowrap;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.4%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.4%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:14.08%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">9,723</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.4%;white-space:nowrap;">  </td> </tr> <tr> <td valign="bottom" style="width:63.4%;"> Research credits</td> <td valign="bottom" style="width:1.42%;">  </td> <td valign="bottom" style="width:1.42%;">  </td> <td valign="bottom" style="width:14.1%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">1,260</td> <td valign="bottom" style="width:1.4%;white-space:nowrap;">  </td> <td valign="bottom" style="width:1.4%;">  </td> <td valign="bottom" style="width:1.4%;">  </td> <td valign="bottom" style="width:14.08%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">1,734</td> <td valign="bottom" style="width:1.4%;white-space:nowrap;">  </td> </tr> <tr> <td valign="bottom" bgcolor="#CFF0FC" style="width:63.4%;"> Other</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.42%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.42%; border-bottom:solid 0.75pt #000000;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:14.1%; border-bottom:solid 0.75pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">1,201</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.4%;white-space:nowrap;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.4%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.4%; border-bottom:solid 0.75pt #000000;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:14.08%; border-bottom:solid 0.75pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">475</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.4%;white-space:nowrap;">  </td> </tr> <tr> <td valign="bottom" style="width:63.4%;"> Gross deferred tax assets</td> <td valign="bottom" style="width:1.42%;">  </td> <td valign="bottom" style="width:1.42%; border-top:solid 0.75pt #000000;">  </td> <td valign="bottom" style="width:14.1%; border-top:solid 0.75pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">24,822</td> <td valign="bottom" style="width:1.4%;white-space:nowrap;">  </td> <td valign="bottom" style="width:1.4%;">  </td> <td valign="bottom" style="width:1.4%; border-top:solid 0.75pt #000000;">  </td> <td valign="bottom" style="width:14.08%; border-top:solid 0.75pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">25,001</td> <td valign="bottom" style="width:1.4%;white-space:nowrap;">  </td> </tr> <tr> <td valign="bottom" bgcolor="#CFF0FC" style="width:63.4%;"> Valuation allowance</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.42%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.42%; border-bottom:solid 0.75pt #000000;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:14.1%; border-bottom:solid 0.75pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">(24,741</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.4%; border-bottom:solid 0.75pt #000000;white-space:nowrap;"> )</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.4%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.4%; border-bottom:solid 0.75pt #000000;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:14.08%; border-bottom:solid 0.75pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">(25,001</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.4%;white-space:nowrap;"> )</td> </tr> <tr> <td valign="bottom" style="width:63.4%;"> Total deferred tax assets </td> <td valign="bottom" style="width:1.42%;">  </td> <td valign="bottom" style="width:1.42%; border-top:solid 0.75pt #000000;">  </td> <td valign="bottom" style="width:14.1%; border-top:solid 0.75pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">81</td> <td valign="bottom" style="width:1.4%; border-top:solid 0.75pt #000000;white-space:nowrap;">  </td> <td valign="bottom" style="width:1.4%;">  </td> <td valign="bottom" style="width:1.4%; border-top:solid 0.75pt #000000;white-space:nowrap;">  </td> <td valign="bottom" style="width:14.08%; border-top:solid 0.75pt #000000;white-space:nowrap;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">—</td> <td valign="bottom" style="width:1.4%;white-space:nowrap;">  </td> </tr> <tr> <td valign="bottom" bgcolor="#CFF0FC" style="width:63.4%;"> Deferred tax liabilities</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.42%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.42%; border-bottom:solid 0.75pt #000000;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:14.1%; border-bottom:solid 0.75pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">(81</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.4%;white-space:nowrap;"> )</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.4%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.4%; border-bottom:solid 0.75pt #000000;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:14.08%; border-bottom:solid 0.75pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">—</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.4%;white-space:nowrap;">  </td> </tr> <tr> <td valign="bottom" style="width:63.4%;"> Net deferred tax assets</td> <td valign="bottom" style="width:1.42%;">  </td> <td valign="bottom" style="width:1.42%; border-top:solid 0.75pt #000000; border-bottom:double 2.5pt #000000;"> $</td> <td valign="bottom" style="width:14.1%; border-top:solid 0.75pt #000000; border-bottom:double 2.5pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">—</td> <td valign="bottom" style="width:1.4%;white-space:nowrap;">  </td> <td valign="bottom" style="width:1.4%;">  </td> <td valign="bottom" style="width:1.4%; border-top:solid 0.75pt #000000; border-bottom:double 2.5pt #000000;white-space:nowrap;"> $</td> <td valign="bottom" style="width:14.08%; border-top:solid 0.75pt #000000; border-bottom:double 2.5pt #000000;white-space:nowrap;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">—</td> <td valign="bottom" style="width:1.4%;white-space:nowrap;">  </td> </tr> </table></div> Realization of deferred tax assets is dependent on future earnings, if any, the timing and amount of which are uncertain. Accordingly, the deferred tax assets have been fully offset by a valuation allowance. The valuation allowance decreased by $0.3 million for the year ended December 31, 2014. The valuation allowance increased by $1.5 million for the year ended December 31, 2013. At December 31, 2014, the Company had net operating loss carryforwards for federal income tax purposes of approximately $28.0 million that expire beginning in 2028 if not utilized, and federal research and development tax credit carryforwards of approximately $2.1 million that expire beginning in 2029 if not utilized. In addition, the Company had net operating loss carryforwards for state income tax purposes of approximately $25.6 million that expire beginning in 2018 if not utilized, and state research and development tax credit carryforwards of approximately $2.3 million, which do not expire. The future utilization of the net operating loss and tax credit carryforwards and credits may be subject to an annual limitation, pursuant to Internal Revenue Code Sections 382 and 383, as a result of ownership changes that may have occurred previously or that could occur in the future.  Due to the existence of the valuation allowance, future changes under Sections 382 and 383 will not impact the Company’s effective tax rate. A reconciliation of the beginning and ending amount of unrecognized tax benefits is as follows:   <div> <table border="0" cellspacing="0" cellpadding="0" align="center" style="border-collapse:collapse; width:80%;"> <tr> <td valign="bottom" style="width:51.8%;">  </td> <td valign="bottom" style="width:1.22%;">  </td> <td colspan="10" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:45.76%; border-bottom:solid 1pt #000000;"> <p style="text-align:center;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:bold;font-size:8pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">December 31,</td> <td valign="bottom" style="width:1.22%;">  </td> </tr> <tr> <td valign="bottom" style="width:51.8%;">  </td> <td valign="bottom" style="width:1.22%;">  </td> <td colspan="2" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:13.62%; border-bottom:solid 0.75pt #000000;"> <p style="text-align:center;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:bold;font-size:8pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">2014</td> <td valign="bottom" style="width:1.22%;">  </td> <td valign="bottom" style="width:1.22%;">   </td> <td colspan="2" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:13.66%; border-bottom:solid 0.75pt #000000;"> <p style="text-align:center;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:bold;font-size:8pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">2013</td> <td valign="bottom" style="width:1.22%;">  </td> <td valign="bottom" style="width:1.22%;">   </td> <td colspan="2" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:13.64%; border-bottom:solid 0.75pt #000000;"> <p style="text-align:center;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:bold;font-size:8pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">2012</td> <td valign="bottom" style="width:1.22%;">  </td> </tr> <tr> <td valign="bottom" style="width:51.8%;">  </td> <td valign="bottom" style="width:1.22%;">  </td> <td colspan="2" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:13.62%;">  </td> <td valign="bottom" style="width:1.22%;">  </td> <td valign="bottom" style="width:1.22%;">  </td> <td colspan="2" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:13.66%;"> <p style="text-align:center;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:bold;font-size:8pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">(in thousands)</td> <td valign="bottom" style="width:1.22%;">  </td> <td valign="bottom" style="width:1.22%;">  </td> <td colspan="2" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:13.64%;">  </td> <td valign="bottom" style="width:1.22%;">  </td> </tr> <tr> <td valign="bottom" bgcolor="#CFF0FC" style="width:51.8%;"> Balance at beginning of year</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.22%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.32%;"> $</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:12.3%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">1,411</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.22%;white-space:nowrap;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.22%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.32%;"> $</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:12.32%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">1,064</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.22%;white-space:nowrap;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.22%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.32%;"> $</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:12.32%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">807</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.22%;white-space:nowrap;">  </td> </tr> <tr> <td valign="bottom" style="width:51.8%;"> Additions based on tax positions related to prior year</td> <td valign="bottom" style="width:1.22%;">  </td> <td valign="bottom" style="width:1.32%;">  </td> <td valign="bottom" style="width:12.3%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">405</td> <td valign="bottom" style="width:1.22%;white-space:nowrap;">  </td> <td valign="bottom" style="width:1.22%;">  </td> <td valign="bottom" style="width:1.32%;">  </td> <td valign="bottom" style="width:12.32%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">—</td> <td valign="bottom" style="width:1.22%;white-space:nowrap;">  </td> <td valign="bottom" style="width:1.22%;">  </td> <td valign="bottom" style="width:1.32%;">  </td> <td valign="bottom" style="width:12.32%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">—</td> <td valign="bottom" style="width:1.22%;white-space:nowrap;">  </td> </tr> <tr> <td valign="bottom" bgcolor="#CFF0FC" style="width:51.8%; border-bottom:solid 0.75pt transparent;"> Additions based on tax positions related to current year</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.22%; border-bottom:solid 0.75pt transparent;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.32%; border-bottom:solid 0.75pt #000000;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:12.3%; border-bottom:solid 0.75pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">999</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.22%; border-bottom:solid 0.75pt transparent;white-space:nowrap;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.22%; border-bottom:solid 0.75pt transparent;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.32%; border-bottom:solid 0.75pt #000000;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:12.32%; border-bottom:solid 0.75pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">347</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.22%; border-bottom:solid 0.75pt transparent;white-space:nowrap;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.22%; border-bottom:solid 0.75pt transparent;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.32%; border-bottom:solid 0.75pt #000000;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:12.32%; border-bottom:solid 0.75pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">257</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.22%; border-bottom:solid 0.75pt transparent;white-space:nowrap;">  </td> </tr> <tr> <td valign="bottom" style="width:51.8%; border-bottom:double 2.5pt transparent;"> Balance at end of year</td> <td valign="bottom" style="width:1.22%; border-bottom:double 2.5pt transparent;">  </td> <td valign="bottom" style="width:1.32%; border-top:solid 0.75pt #000000; border-bottom:double 2.5pt #000000;"> $</td> <td valign="bottom" style="width:12.3%; border-top:solid 0.75pt #000000; border-bottom:double 2.5pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">2,815</td> <td valign="bottom" style="width:1.22%; border-bottom:double 2.5pt transparent;white-space:nowrap;">  </td> <td valign="bottom" style="width:1.22%; border-bottom:double 2.5pt transparent;">  </td> <td valign="bottom" style="width:1.32%; border-top:solid 0.75pt #000000; border-bottom:double 2.5pt #000000;"> $</td> <td valign="bottom" style="width:12.32%; border-top:solid 0.75pt #000000; border-bottom:double 2.5pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">1,411</td> <td valign="bottom" style="width:1.22%; border-bottom:double 2.5pt transparent;white-space:nowrap;">  </td> <td valign="bottom" style="width:1.22%; border-bottom:double 2.5pt transparent;">  </td> <td valign="bottom" style="width:1.32%; border-top:solid 0.75pt #000000; border-bottom:double 2.5pt #000000;"> $</td> <td valign="bottom" style="width:12.32%; border-top:solid 0.75pt #000000; border-bottom:double 2.5pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">1,064</td> <td valign="bottom" style="width:1.22%; border-bottom:double 2.5pt transparent;white-space:nowrap;">  </td> </tr> </table></div> The unrecognized tax benefits, if recognized and in absence of full valuation allowance, would impact the income tax provision by $2.8 million, $1.4 million and $1.1 million as of December 31, 2014, 2013 and 2012, respectively. The Company has elected to include interest and penalties as a component of tax expense. During the years ended December 31, 2014, 2013 and 2012, the Company did not recognize accrued interest and penalties related to unrecognized tax benefits. Although the timing and outcome of income tax audit is highly uncertain, the Company does not anticipate that the amount of existing unrecognized tax benefits will significantly change during the next 12 months. The Company files income tax returns in the U.S. federal and California tax jurisdictions. Due to the Company’s net operating loss and tax credit carryforwards, the income tax returns remain open to U.S. federal and California state tax examinations.   The Company is not currently under examination in any tax jurisdiction.</div>

<div> Use of Estimates The preparation of financial statements in conformity with accounting principles generally accepted in the United States requires management to make estimates and judgments that affect the amounts reported in the financial statements and accompanying notes. On an ongoing basis, management evaluates its estimates, including those related to revenue recognition, clinical trial accruals, income taxes, and stock-based compensation. Management bases its estimates on historical experience and on various other market-specific and relevant assumptions that management believes to be reasonable under the circumstances. Actual results may differ from those estimates. </div>

<div> Income Taxes The Company uses the asset and liability method of accounting for income taxes. Under this method, deferred tax assets and liabilities are determined based on the differences between the financial reporting and the tax bases of assets and liabilities and are measured using the enacted tax rates and laws that will be in effect when the differences are expected to reverse. A valuation allowance is provided when it is more likely than not that some portion or all of a deferred tax asset will not be realized. </div>

<div> Revenue Recognition Revenue from research activities made under collaboration partnership agreements are recognized as the services are provided and when there is persuasive evidence that an arrangement exists, delivery has occurred, the price is fixed or determinable, and collectability is reasonably assured. Revenue generated from research and licensing agreements typically includes up-front signing or license fees, cost reimbursements, research services, minimum sublicense fees, milestone payments, and royalties on future licensees’ product sales. For revenue agreements with multiple-element arrangements, such as license and development agreements, the Company allocates revenue to each unit of accounting based on the relative selling price of each unit. When applying the relative selling price method, the Company determines the selling price for each deliverable using vendor-specific objective evidence or third-party evidence. If neither exists, the Company uses its best estimate of selling price for that deliverable. Revenue allocated is then recognized when the four basic revenue recognition criteria are met for each deliverable. The Company recognizes revenue from upfront payments ratably over the term of its estimated period of performance under the agreement which is recorded as licensing revenue. Reimbursements for development costs incurred under the Company’s license agreement with AstraZeneca are classified as collaborative development revenue. The Company recognizes cost reimbursement revenue under collaboration partnership agreements as the related research and development costs for services are rendered. Deferred revenue represents the portion of research or license payments received which has not been earned. Revenues from milestones, if they are nonrefundable and deemed substantive, are recognized upon successful accomplishment of the milestones. To the extent that non-substantive milestones are achieved and the Company has remaining performance obligations, milestones are deferred and recognized as revenue over the estimated remaining period of performance. The Company will recognize revenue associated with the non-substantive milestones upon achievement of the milestone if there are no undelivered units and it has no remaining performance obligations. The Company will account for sales-based milestones as royalties that will be recognized as revenue upon achievement of the milestone. </div>

<div> Recent Accounting Pronouncements In July 2013, the Financial Accounting Standards Board, or FASB, issued Accounting Standards Update (“ASU”) 2013-11, Presentation of an Unrecognized Tax Benefit When a Net Operating Loss Carryforward, a Similar Tax Loss, or a Tax Credit Carryforward Exists. The ASU concludes an unrecognized tax benefit should be presented as a reduction of a deferred tax asset when settlement in this manner is available under the law. The Company adopted this amendment as of January 1, 2014, which did not have a significant impact on the balance sheet. In May 2014, the FASB issued Accounting Standards Update 2014-09, Revenue from Contracts with Customers (“ASU 2014-09”), which converges the FASB and the International Accounting Standards Board standards on revenue recognition and will replace nearly all existing revenue recognition under U.S. GAAP. The core principle of ASU 2014-09 is that an entity should recognize revenue when it transfers promised goods or services to customers in an amount that reflects the consideration to which the entity expects to be entitled in exchange for those goods or services. This guidance is effective for the fiscal years and interim reporting periods beginning after December 15, 2016, at which time the Company may adopt the new standard under the full retrospective method or the modified retrospective method. Early adoption is not permitted. The Company has not yet selected a transition method nor has the Company determined the impact of the new standard on its financial statements and related disclosures. In August 2014, the Financial Accounting Standards Board issued Accounting Standards Update No. 2014-15, Disclosure of Uncertainties about an Entity’s Ability to Continue as a Going Concern (“ASU 2014-15”). ASU 2014-15 requires management to evaluate whether there is substantial doubt about an entity’s ability to continue as a going concern and to provide related footnote disclosures. In doing so, companies will have reduced diversity in the timing and content of footnote disclosures than under today’s guidance. ASU 2014-15 is effective for the Company in the first quarter of 2016 with early adoption permitted. The Company does not believe the impact of adopting ASU 2014-15 on its financial statements will be material. </div>

<div> The following table sets forth the fair value of the Company’s financial assets and liabilities measured on a recurring basis by level within the fair value hierarchy:   <div> <table border="0" cellspacing="0" cellpadding="0" align="center" style="border-collapse:collapse; width:90%;"> <tr> <td valign="bottom" style="width:47.26%;">  </td> <td valign="bottom" style="width:1.08%;">  </td> <td colspan="14" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:50.56%; border-bottom:solid 1pt #000000;"> <p style="text-align:center;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:bold;font-size:8pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">December 31, 2014</td> <td valign="bottom" style="width:1.1%;">  </td> </tr> <tr> <td valign="bottom" style="width:47.26%;">  </td> <td valign="bottom" style="width:1.08%;">  </td> <td colspan="2" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:10.98%; border-bottom:solid 0.75pt #000000;"> <p style="text-align:center;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:bold;font-size:8pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">Total</td> <td valign="bottom" style="width:1.08%;">  </td> <td valign="bottom" style="width:1.08%;">   </td> <td colspan="2" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:11%; border-bottom:solid 0.75pt #000000;"> <p style="text-align:center;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:bold;font-size:8pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">Level 1</td> <td valign="bottom" style="width:1.1%;">  </td> <td valign="bottom" style="width:1.1%;">   </td> <td colspan="2" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:11%; border-bottom:solid 0.75pt #000000;"> <p style="text-align:center;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:bold;font-size:8pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">Level 2</td> <td valign="bottom" style="width:1.1%;">  </td> <td valign="bottom" style="width:1.1%;">   </td> <td colspan="2" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:11%; border-bottom:solid 0.75pt #000000;"> <p style="text-align:center;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:bold;font-size:8pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">Level 3</td> <td valign="bottom" style="width:1.1%;">  </td> </tr> <tr> <td valign="bottom" style="width:47.26%;">  </td> <td valign="bottom" style="width:1.08%;">  </td> <td colspan="2" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:10.98%;">  </td> <td valign="bottom" style="width:1.08%;">  </td> <td valign="bottom" style="width:1.08%;">  </td> <td colspan="2" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:11%;">  </td> <td valign="bottom" style="width:1.1%;">  </td> <td valign="bottom" style="width:1.1%;">  </td> <td colspan="2" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:11%;">  </td> <td valign="bottom" style="width:1.1%;">  </td> <td valign="bottom" style="width:1.1%;">  </td> <td colspan="2" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:11%;">  </td> <td valign="bottom" style="width:1.1%;">  </td> </tr> <tr> <td valign="bottom" style="width:47.26%;">  </td> <td valign="bottom" style="width:1.08%;">  </td> <td colspan="2" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:10.98%;">  </td> <td valign="bottom" style="width:1.08%;">  </td> <td valign="bottom" style="width:1.08%;">  </td> <td colspan="6" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:24.2%;"> <p style="text-align:center;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:bold;font-size:8pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">(in thousands)</td> <td valign="bottom" style="width:1.1%;">  </td> <td valign="bottom" style="width:1.1%;">  </td> <td colspan="2" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:11%;">  </td> <td valign="bottom" style="width:1.1%;">  </td> </tr> <tr> <td valign="bottom" bgcolor="#CFF0FC" style="width:47.26%;"> Assets:</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.08%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.08%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:9.9%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.08%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.08%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.08%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:9.9%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:9.9%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:9.9%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.1%;">  </td> </tr> <tr> <td valign="bottom" style="width:47.26%;"> Money market funds</td> <td valign="bottom" style="width:1.08%;">  </td> <td valign="bottom" style="width:1.08%;"> $</td> <td valign="bottom" style="width:9.9%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">105,410</td> <td valign="bottom" style="width:1.08%;white-space:nowrap;">  </td> <td valign="bottom" style="width:1.08%;">  </td> <td valign="bottom" style="width:1.08%;"> $</td> <td valign="bottom" style="width:9.9%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">105,410</td> <td valign="bottom" style="width:1.1%;white-space:nowrap;">  </td> <td valign="bottom" style="width:1.1%;">  </td> <td valign="bottom" style="width:1.1%;"> $</td> <td valign="bottom" style="width:9.9%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">—</td> <td valign="bottom" style="width:1.1%;white-space:nowrap;">  </td> <td valign="bottom" style="width:1.1%;">  </td> <td valign="bottom" style="width:1.1%;white-space:nowrap;"> $</td> <td valign="bottom" style="width:9.9%;white-space:nowrap;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">—</td> <td valign="bottom" style="width:1.1%;white-space:nowrap;">  </td> </tr> <tr> <td valign="bottom" bgcolor="#CFF0FC" style="width:47.26%; border-bottom:solid 0.75pt transparent;"> Certificates of deposit</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.08%; border-bottom:solid 0.75pt transparent;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.08%; border-bottom:solid 0.75pt #000000;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:9.9%; border-bottom:solid 0.75pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">100</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.08%; border-bottom:solid 0.75pt transparent;white-space:nowrap;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.08%; border-bottom:solid 0.75pt transparent;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.08%; border-bottom:solid 0.75pt #000000;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:9.9%; border-bottom:solid 0.75pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">—</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.1%; border-bottom:solid 0.75pt transparent;white-space:nowrap;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.1%; border-bottom:solid 0.75pt transparent;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.1%; border-bottom:solid 0.75pt #000000;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:9.9%; border-bottom:solid 0.75pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">100</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.1%; border-bottom:solid 0.75pt transparent;white-space:nowrap;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.1%; border-bottom:solid 0.75pt transparent;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.1%; border-bottom:solid 0.75pt #000000;white-space:nowrap;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:9.9%; border-bottom:solid 0.75pt #000000;white-space:nowrap;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">—</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.1%; border-bottom:solid 0.75pt transparent;white-space:nowrap;">  </td> </tr> <tr> <td valign="bottom" style="width:47.26%; border-bottom:double 2.5pt transparent;"> Total</td> <td valign="bottom" style="width:1.08%; border-bottom:double 2.5pt transparent;">  </td> <td valign="bottom" style="width:1.08%; border-top:solid 0.75pt #000000; border-bottom:double 2.5pt #000000;"> $</td> <td valign="bottom" style="width:9.9%; border-top:solid 0.75pt #000000; border-bottom:double 2.5pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">105,510</td> <td valign="bottom" style="width:1.08%; border-bottom:double 2.5pt transparent;white-space:nowrap;">  </td> <td valign="bottom" style="width:1.08%; border-bottom:double 2.5pt transparent;">  </td> <td valign="bottom" style="width:1.08%; border-top:solid 0.75pt #000000; border-bottom:double 2.5pt #000000;"> $</td> <td valign="bottom" style="width:9.9%; border-top:solid 0.75pt #000000; border-bottom:double 2.5pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">105,410</td> <td valign="bottom" style="width:1.1%; border-bottom:double 2.5pt transparent;white-space:nowrap;">  </td> <td valign="bottom" style="width:1.1%; border-bottom:double 2.5pt transparent;">  </td> <td valign="bottom" style="width:1.1%; border-top:solid 0.75pt #000000; border-bottom:double 2.5pt #000000;"> $</td> <td valign="bottom" style="width:9.9%; border-top:solid 0.75pt #000000; border-bottom:double 2.5pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">100</td> <td valign="bottom" style="width:1.1%; border-bottom:double 2.5pt transparent;white-space:nowrap;">  </td> <td valign="bottom" style="width:1.1%; border-bottom:double 2.5pt transparent;">  </td> <td valign="bottom" style="width:1.1%; border-top:solid 0.75pt #000000; border-bottom:double 2.5pt #000000;white-space:nowrap;"> $</td> <td valign="bottom" style="width:9.9%; border-top:solid 0.75pt #000000; border-bottom:double 2.5pt #000000;white-space:nowrap;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">—</td> <td valign="bottom" style="width:1.1%; border-bottom:double 2.5pt transparent;white-space:nowrap;">  </td> </tr> </table></div>   <div> <table border="0" cellspacing="0" cellpadding="0" align="center" style="border-collapse:collapse; width:90%;"> <tr> <td valign="bottom" style="width:47.26%;">  </td> <td valign="bottom" style="width:1.08%;">  </td> <td colspan="14" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:50.56%; border-bottom:solid 1pt #000000;"> <p style="text-align:center;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:bold;font-size:8pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">December 31, 2013</td> <td valign="bottom" style="width:1.1%;">  </td> </tr> <tr> <td valign="bottom" style="width:47.26%;">  </td> <td valign="bottom" style="width:1.08%;">  </td> <td colspan="2" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:10.98%; border-bottom:solid 0.75pt #000000;"> <p style="text-align:center;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:bold;font-size:8pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">Total</td> <td valign="bottom" style="width:1.08%;">  </td> <td valign="bottom" style="width:1.08%;">   </td> <td colspan="2" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:11%; border-bottom:solid 0.75pt #000000;"> <p style="text-align:center;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:bold;font-size:8pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">Level 1</td> <td valign="bottom" style="width:1.1%;">  </td> <td valign="bottom" style="width:1.1%;">   </td> <td colspan="2" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:11%; border-bottom:solid 0.75pt #000000;"> <p style="text-align:center;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:bold;font-size:8pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">Level 2</td> <td valign="bottom" style="width:1.1%;">  </td> <td valign="bottom" style="width:1.1%;">   </td> <td colspan="2" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:11%; border-bottom:solid 0.75pt #000000;"> <p style="text-align:center;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:bold;font-size:8pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">Level 3</td> <td valign="bottom" style="width:1.1%;">  </td> </tr> <tr> <td valign="bottom" style="width:47.26%;">  </td> <td valign="bottom" style="width:1.08%;">  </td> <td colspan="2" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:10.98%;">  </td> <td valign="bottom" style="width:1.08%;">  </td> <td valign="bottom" style="width:1.08%;">  </td> <td colspan="2" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:11%;">  </td> <td valign="bottom" style="width:1.1%;">  </td> <td valign="bottom" style="width:1.1%;">  </td> <td colspan="2" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:11%;">  </td> <td valign="bottom" style="width:1.1%;">  </td> <td valign="bottom" style="width:1.1%;">  </td> <td colspan="2" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:11%;">  </td> <td valign="bottom" style="width:1.1%;">  </td> </tr> <tr> <td valign="bottom" style="width:47.26%;">  </td> <td valign="bottom" style="width:1.08%;">  </td> <td colspan="2" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:10.98%;">  </td> <td valign="bottom" style="width:1.08%;">  </td> <td valign="bottom" style="width:1.08%;">  </td> <td colspan="6" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:24.2%;"> <p style="text-align:center;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:bold;font-size:8pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">(in thousands)</td> <td valign="bottom" style="width:1.1%;">  </td> <td valign="bottom" style="width:1.1%;">  </td> <td colspan="2" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:11%;">  </td> <td valign="bottom" style="width:1.1%;">  </td> </tr> <tr> <td valign="bottom" bgcolor="#CFF0FC" style="width:47.26%;"> Assets:</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.08%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.08%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:9.9%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.08%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.08%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.08%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:9.9%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:9.9%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:9.9%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.1%;">  </td> </tr> <tr> <td valign="bottom" style="width:47.26%;"> Money market funds</td> <td valign="bottom" style="width:1.08%;">  </td> <td valign="bottom" style="width:1.08%;"> $</td> <td valign="bottom" style="width:9.9%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">32,472</td> <td valign="bottom" style="width:1.08%;white-space:nowrap;">  </td> <td valign="bottom" style="width:1.08%;">  </td> <td valign="bottom" style="width:1.08%;"> $</td> <td valign="bottom" style="width:9.9%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">32,472</td> <td valign="bottom" style="width:1.1%;white-space:nowrap;">  </td> <td valign="bottom" style="width:1.1%;">  </td> <td valign="bottom" style="width:1.1%;white-space:nowrap;"> $</td> <td valign="bottom" style="width:9.9%;white-space:nowrap;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">—</td> <td valign="bottom" style="width:1.1%;white-space:nowrap;">  </td> <td valign="bottom" style="width:1.1%;">  </td> <td valign="bottom" style="width:1.1%;white-space:nowrap;"> $</td> <td valign="bottom" style="width:9.9%;white-space:nowrap;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">—</td> <td valign="bottom" style="width:1.1%;white-space:nowrap;">  </td> </tr> <tr> <td valign="bottom" bgcolor="#CFF0FC" style="width:47.26%; border-bottom:solid 0.75pt transparent;"> Certificates of deposit</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.08%; border-bottom:solid 0.75pt transparent;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.08%; border-bottom:solid 0.75pt #000000;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:9.9%; border-bottom:solid 0.75pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">180</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.08%; border-bottom:solid 0.75pt transparent;white-space:nowrap;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.08%; border-bottom:solid 0.75pt transparent;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.08%; border-bottom:solid 0.75pt #000000;white-space:nowrap;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:9.9%; border-bottom:solid 0.75pt #000000;white-space:nowrap;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">—</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.1%; border-bottom:solid 0.75pt transparent;white-space:nowrap;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.1%; border-bottom:solid 0.75pt transparent;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.1%; border-bottom:solid 0.75pt #000000;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:9.9%; border-bottom:solid 0.75pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">180</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.1%; border-bottom:solid 0.75pt transparent;white-space:nowrap;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.1%; border-bottom:solid 0.75pt transparent;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.1%; border-bottom:solid 0.75pt #000000;white-space:nowrap;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:9.9%; border-bottom:solid 0.75pt #000000;white-space:nowrap;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">—</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.1%; border-bottom:solid 0.75pt transparent;white-space:nowrap;">  </td> </tr> <tr> <td valign="bottom" style="width:47.26%; border-bottom:double 2.5pt transparent;"> Total</td> <td valign="bottom" style="width:1.08%; border-bottom:double 2.5pt transparent;">  </td> <td valign="bottom" style="width:1.08%; border-top:solid 0.75pt #000000; border-bottom:double 2.5pt #000000;"> $</td> <td valign="bottom" style="width:9.9%; border-top:solid 0.75pt #000000; border-bottom:double 2.5pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">32,652</td> <td valign="bottom" style="width:1.08%; border-bottom:double 2.5pt transparent;white-space:nowrap;">  </td> <td valign="bottom" style="width:1.08%; border-bottom:double 2.5pt transparent;">  </td> <td valign="bottom" style="width:1.08%; border-top:solid 0.75pt #000000; border-bottom:double 2.5pt #000000;"> $</td> <td valign="bottom" style="width:9.9%; border-top:solid 0.75pt #000000; border-bottom:double 2.5pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">32,472</td> <td valign="bottom" style="width:1.1%; border-bottom:double 2.5pt transparent;white-space:nowrap;">  </td> <td valign="bottom" style="width:1.1%; border-bottom:double 2.5pt transparent;">  </td> <td valign="bottom" style="width:1.1%; border-top:solid 0.75pt #000000; border-bottom:double 2.5pt #000000;"> $</td> <td valign="bottom" style="width:9.9%; border-top:solid 0.75pt #000000; border-bottom:double 2.5pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">180</td> <td valign="bottom" style="width:1.1%; border-bottom:double 2.5pt transparent;white-space:nowrap;">  </td> <td valign="bottom" style="width:1.1%; border-bottom:double 2.5pt transparent;">  </td> <td valign="bottom" style="width:1.1%; border-top:solid 0.75pt #000000; border-bottom:double 2.5pt #000000;white-space:nowrap;"> $</td> <td valign="bottom" style="width:9.9%; border-top:solid 0.75pt #000000; border-bottom:double 2.5pt #000000;white-space:nowrap;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">—</td> <td valign="bottom" style="width:1.1%; border-bottom:double 2.5pt transparent;white-space:nowrap;">  </td> </tr> <tr> <td valign="bottom" bgcolor="#CFF0FC" style="width:47.26%;"> Liabilities:</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.08%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.08%; border-top:double 2.5pt #000000;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:9.9%; border-top:double 2.5pt #000000;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.08%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.08%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.08%; border-top:double 2.5pt #000000;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:9.9%; border-top:double 2.5pt #000000;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.1%; border-top:double 2.5pt #000000;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:9.9%; border-top:double 2.5pt #000000;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.1%; border-top:double 2.5pt #000000;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:9.9%; border-top:double 2.5pt #000000;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.1%;">  </td> </tr> <tr> <td valign="bottom" style="width:47.26%; border-bottom:solid 0.75pt transparent;"> Convertible preferred stock warrant liability</td> <td valign="bottom" style="width:1.08%; border-bottom:solid 0.75pt transparent;">  </td> <td valign="bottom" style="width:1.08%; border-bottom:solid 0.75pt #000000;"> $</td> <td valign="bottom" style="width:9.9%; border-bottom:solid 0.75pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">6,456</td> <td valign="bottom" style="width:1.08%; border-bottom:solid 0.75pt transparent;white-space:nowrap;">  </td> <td valign="bottom" style="width:1.08%; border-bottom:solid 0.75pt transparent;">  </td> <td valign="bottom" style="width:1.08%; border-bottom:solid 0.75pt #000000;white-space:nowrap;"> $</td> <td valign="bottom" style="width:9.9%; border-bottom:solid 0.75pt #000000;white-space:nowrap;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">—</td> <td valign="bottom" style="width:1.1%; border-bottom:solid 0.75pt transparent;white-space:nowrap;">  </td> <td valign="bottom" style="width:1.1%; border-bottom:solid 0.75pt transparent;">  </td> <td valign="bottom" style="width:1.1%; border-bottom:solid 0.75pt #000000;white-space:nowrap;"> $</td> <td valign="bottom" style="width:9.9%; border-bottom:solid 0.75pt #000000;white-space:nowrap;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">—</td> <td valign="bottom" style="width:1.1%; border-bottom:solid 0.75pt transparent;white-space:nowrap;">  </td> <td valign="bottom" style="width:1.1%; border-bottom:solid 0.75pt transparent;">  </td> <td valign="bottom" style="width:1.1%; border-bottom:solid 0.75pt #000000;"> $</td> <td valign="bottom" style="width:9.9%; border-bottom:solid 0.75pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">6,456</td> <td valign="bottom" style="width:1.1%; border-bottom:solid 0.75pt transparent;white-space:nowrap;">  </td> </tr> <tr> <td valign="bottom" bgcolor="#CFF0FC" style="width:47.26%; border-bottom:double 2.5pt transparent;"> Total</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.08%; border-bottom:double 2.5pt transparent;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.08%; border-top:solid 0.75pt #000000; border-bottom:double 2.5pt #000000;"> $</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:9.9%; border-top:solid 0.75pt #000000; border-bottom:double 2.5pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">6,456</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.08%; border-bottom:double 2.5pt transparent;white-space:nowrap;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.08%; border-bottom:double 2.5pt transparent;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.08%; border-top:solid 0.75pt #000000; border-bottom:double 2.5pt #000000;white-space:nowrap;"> $</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:9.9%; border-top:solid 0.75pt #000000; border-bottom:double 2.5pt #000000;white-space:nowrap;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">—</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.1%; border-bottom:double 2.5pt transparent;white-space:nowrap;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.1%; border-bottom:double 2.5pt transparent;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.1%; border-top:solid 0.75pt #000000; border-bottom:double 2.5pt #000000;white-space:nowrap;"> $</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:9.9%; border-top:solid 0.75pt #000000; border-bottom:double 2.5pt #000000;white-space:nowrap;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">—</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.1%; border-bottom:double 2.5pt transparent;white-space:nowrap;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.1%; border-bottom:double 2.5pt transparent;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.1%; border-top:solid 0.75pt #000000; border-bottom:double 2.5pt #000000;"> $</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:9.9%; border-top:solid 0.75pt #000000; border-bottom:double 2.5pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">6,456</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.1%; border-bottom:double 2.5pt transparent;white-space:nowrap;">  </td> </tr> </table></div>  </div>

<div> The following table sets forth a summary of the changes in the estimated fair value of the Company’s preferred stock warrants which were measured at fair value on a recurring basis (in thousands):   <div> <table border="0" cellspacing="0" cellpadding="0" align="center" style="border-collapse:collapse; width:70%;"> <tr> <td valign="bottom" style="width:46%;">  </td> <td valign="bottom" style="width:1%;">  </td> <td colspan="2" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:1%; border-bottom:solid 1pt #000000;"> <p style="text-align:center;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:bold;font-size:8pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">Preferred Stock Warrant Liability</td> <td valign="bottom" style="width:1%;">  </td> </tr> <tr> <td valign="bottom" style="width:46%;">  </td> <td valign="bottom" style="width:1%;">  </td> <td colspan="2" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:1%;"> <p style="text-align:center;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:bold;font-size:8pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">(in thousands)</td> <td valign="bottom" style="width:1%;">  </td> </tr> <tr> <td valign="bottom" bgcolor="#CFF0FC" style="width:46%;"> Balance at December 31, 2012</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;"> $</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:12%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">2,950</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;white-space:nowrap;">  </td> </tr> <tr> <td valign="bottom" style="width:46%; border-bottom:solid 0.75pt transparent;"> Net increase in fair value of warrant liabilities upon revaluation</td> <td valign="bottom" style="width:1%; border-bottom:solid 0.75pt transparent;">  </td> <td valign="bottom" style="width:1%; border-bottom:solid 0.75pt #000000;">  </td> <td valign="bottom" style="width:12%; border-bottom:solid 0.75pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">3,506</td> <td valign="bottom" style="width:1%; border-bottom:solid 0.75pt transparent;white-space:nowrap;">  </td> </tr> <tr> <td valign="bottom" bgcolor="#CFF0FC" style="width:46%;"> Balance at December 31, 2013</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%; border-top:solid 0.75pt #000000;"> $</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:12%; border-top:solid 0.75pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">6,456</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;white-space:nowrap;">  </td> </tr> <tr> <td valign="bottom" style="width:46%;"> Net increase in fair value of warrant liabilities upon revaluation</td> <td valign="bottom" style="width:1%;">  </td> <td valign="bottom" style="width:1%;">  </td> <td valign="bottom" style="width:12%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">1,593</td> <td valign="bottom" style="width:1%;white-space:nowrap;">  </td> </tr> <tr> <td valign="bottom" bgcolor="#CFF0FC" style="width:46%; border-bottom:solid 0.75pt transparent;"> Reclassification of warrant liability to additional paid-in capital upon completion of IPO</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%; border-bottom:solid 0.75pt transparent;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%; border-bottom:solid 0.75pt #000000;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:12%; border-bottom:solid 0.75pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">(8,049</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%; border-bottom:solid 0.75pt transparent;white-space:nowrap;"> )</td> </tr> <tr> <td valign="bottom" style="width:46%; border-bottom:double 2.5pt transparent;"> Balance at December 31, 2014</td> <td valign="bottom" style="width:1%; border-bottom:double 2.5pt transparent;">  </td> <td valign="bottom" style="width:1%; border-top:solid 0.75pt #000000; border-bottom:double 2.5pt #000000;white-space:nowrap;"> $</td> <td valign="bottom" style="width:12%; border-top:solid 0.75pt #000000; border-bottom:double 2.5pt #000000;white-space:nowrap;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">—</td> <td valign="bottom" style="width:1%; border-bottom:double 2.5pt transparent;white-space:nowrap;">  </td> </tr> </table></div>  </div>

<div> Property and equipment consist of the following:   <div> <table border="0" cellspacing="0" cellpadding="0" align="center" style="border-collapse:collapse; width:70%;"> <tr> <td valign="bottom" style="width:63.4%;">  </td> <td valign="bottom" style="width:1.42%;">  </td> <td colspan="6" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:33.8%; border-bottom:solid 1pt #000000;"> <p style="text-align:center;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:bold;font-size:8pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">December 31,</td> <td valign="bottom" style="width:1.4%;">  </td> </tr> <tr> <td valign="bottom" style="width:63.4%;">  </td> <td valign="bottom" style="width:1.42%;">  </td> <td colspan="2" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:15.5%; border-bottom:solid 0.75pt #000000;"> <p style="text-align:center;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:bold;font-size:8pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">2014</td> <td valign="bottom" style="width:1.4%;">  </td> <td valign="bottom" style="width:1.4%;">   </td> <td colspan="2" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:15.48%; border-bottom:solid 0.75pt #000000;"> <p style="text-align:center;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:bold;font-size:8pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">2013</td> <td valign="bottom" style="width:1.4%;">  </td> </tr> <tr> <td valign="bottom" style="width:63.4%;">  </td> <td valign="bottom" style="width:1.42%;">  </td> <td colspan="2" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:15.5%;">  </td> <td valign="bottom" style="width:1.4%;">  </td> <td valign="bottom" style="width:1.4%;">  </td> <td colspan="2" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:15.48%;">  </td> <td valign="bottom" style="width:1.4%;">  </td> </tr> <tr> <td valign="bottom" style="width:63.4%;">  </td> <td valign="bottom" style="width:1.42%;">  </td> <td colspan="6" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:33.8%;"> <p style="text-align:center;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:bold;font-size:8pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">(in thousands)</td> <td valign="bottom" style="width:1.4%;">  </td> </tr> <tr> <td valign="bottom" bgcolor="#CFF0FC" style="width:63.4%;"> Laboratory equipment</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.42%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.42%;"> $</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:14.1%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">3,039</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.4%;white-space:nowrap;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.4%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.4%;"> $</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:14.08%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">2,315</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.4%;white-space:nowrap;">  </td> </tr> <tr> <td valign="bottom" style="width:63.4%;"> Office equipment and furniture</td> <td valign="bottom" style="width:1.42%;">  </td> <td valign="bottom" style="width:1.42%;">  </td> <td valign="bottom" style="width:14.1%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">229</td> <td valign="bottom" style="width:1.4%;white-space:nowrap;">  </td> <td valign="bottom" style="width:1.4%;">  </td> <td valign="bottom" style="width:1.4%;">  </td> <td valign="bottom" style="width:14.08%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">91</td> <td valign="bottom" style="width:1.4%;white-space:nowrap;">  </td> </tr> <tr> <td valign="bottom" bgcolor="#CFF0FC" style="width:63.4%;"> Construction in progress</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.42%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.42%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:14.1%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">362</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.4%;white-space:nowrap;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.4%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.4%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:14.08%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">—</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.4%;white-space:nowrap;">  </td> </tr> <tr> <td valign="bottom" style="width:63.4%;"> Leasehold improvements</td> <td valign="bottom" style="width:1.42%;">  </td> <td valign="bottom" style="width:1.42%; border-bottom:solid 0.75pt #000000;">  </td> <td valign="bottom" style="width:14.1%; border-bottom:solid 0.75pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">2,135</td> <td valign="bottom" style="width:1.4%;white-space:nowrap;">  </td> <td valign="bottom" style="width:1.4%;">  </td> <td valign="bottom" style="width:1.4%; border-bottom:solid 0.75pt #000000;">  </td> <td valign="bottom" style="width:14.08%; border-bottom:solid 0.75pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">1,456</td> <td valign="bottom" style="width:1.4%;white-space:nowrap;">  </td> </tr> <tr> <td valign="bottom" bgcolor="#CFF0FC" style="width:63.4%;"> Property and equipment, gross</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.42%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.42%; border-top:solid 0.75pt #000000;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:14.1%; border-top:solid 0.75pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">5,765</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.4%;white-space:nowrap;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.4%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.4%; border-top:solid 0.75pt #000000;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:14.08%; border-top:solid 0.75pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">3,862</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.4%;white-space:nowrap;">  </td> </tr> <tr> <td valign="bottom" style="width:63.4%;"> Less: accumulated depreciation and amortization</td> <td valign="bottom" style="width:1.42%;">  </td> <td valign="bottom" style="width:1.42%; border-bottom:solid 0.75pt #000000;">  </td> <td valign="bottom" style="width:14.1%; border-bottom:solid 0.75pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">(3,634</td> <td valign="bottom" style="width:1.4%;white-space:nowrap;"> )</td> <td valign="bottom" style="width:1.4%;">  </td> <td valign="bottom" style="width:1.4%; border-bottom:solid 0.75pt #000000;">  </td> <td valign="bottom" style="width:14.08%; border-bottom:solid 0.75pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">(3,332</td> <td valign="bottom" style="width:1.4%;white-space:nowrap;"> )</td> </tr> <tr> <td valign="bottom" bgcolor="#CFF0FC" style="width:63.4%;"> Total property and equipment, net</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.42%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.42%; border-top:solid 0.75pt #000000; border-bottom:double 2.5pt #000000;"> $</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:14.1%; border-top:solid 0.75pt #000000; border-bottom:double 2.5pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">2,131</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.4%;white-space:nowrap;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.4%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.4%; border-top:solid 0.75pt #000000; border-bottom:double 2.5pt #000000;"> $</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:14.08%; border-top:solid 0.75pt #000000; border-bottom:double 2.5pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">530</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.4%;white-space:nowrap;">  </td> </tr> </table></div>  </div>

<div> Convertible preferred stock as of December 31, 2013 consisted of the following:   <div> <table border="0" cellspacing="0" cellpadding="0" align="center" style="border-collapse:collapse; width:90%;"> <tr> <td valign="bottom" style="width:42.86%; border-bottom:solid 0.75pt #000000;white-space:nowrap;"> Convertible Preferred Stock:</td> <td valign="bottom" style="width:1.08%;">  </td> <td colspan="2" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:12.06%; border-bottom:solid 0.75pt #000000;"> <p style="text-align:center;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:bold;font-size:8pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">Shares Authorized</td> <td valign="bottom" style="width:1.08%;">  </td> <td valign="bottom" style="width:1.08%;">   </td> <td colspan="2" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:12.06%; border-bottom:solid 0.75pt #000000;"> <p style="text-align:center;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:bold;font-size:8pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">Shares Issued and Outstanding</td> <td valign="bottom" style="width:1.08%;">  </td> <td valign="bottom" style="width:1.08%;">   </td> <td colspan="2" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:12.14%; border-bottom:solid 0.75pt #000000;"> <p style="text-align:center;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:bold;font-size:8pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">Net Carrying Value</td> <td valign="bottom" style="width:1.08%;">  </td> <td valign="bottom" style="width:1.08%;">   </td> <td colspan="2" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:12.16%; border-bottom:solid 0.75pt #000000;"> <p style="text-align:center;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:bold;font-size:8pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">Aggregate Liquidation Preference</td> <td valign="bottom" style="width:1.1%;">  </td> </tr> <tr> <td valign="bottom" style="width:42.86%;white-space:nowrap;">  </td> <td valign="bottom" style="width:1.08%;">  </td> <td colspan="2" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:12.06%;">  </td> <td valign="bottom" style="width:1.08%;">  </td> <td valign="bottom" style="width:1.08%;">  </td> <td colspan="2" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:12.06%;">  </td> <td valign="bottom" style="width:1.08%;">  </td> <td valign="bottom" style="width:1.08%;">  </td> <td colspan="2" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:12.14%;">  </td> <td valign="bottom" style="width:1.08%;">  </td> <td valign="bottom" style="width:1.08%;">  </td> <td colspan="2" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:12.16%;">  </td> <td valign="bottom" style="width:1.1%;">  </td> </tr> <tr> <td valign="bottom" style="width:42.86%;">  </td> <td valign="bottom" style="width:1.08%;">  </td> <td colspan="14" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:54.96%;"> <p style="text-align:center;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:bold;font-size:8pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">(In thousands, except share data)</td> <td valign="bottom" style="width:1.1%;">  </td> </tr> <tr> <td valign="bottom" bgcolor="#CFF0FC" style="width:42.86%;"> Series A</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.08%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.08%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:10.98%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">25,231,213</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.08%;white-space:nowrap;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.08%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.08%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:10.98%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">2,803,462</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.08%;white-space:nowrap;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.08%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.18%;"> $</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:10.98%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">25,957</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.08%;white-space:nowrap;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.08%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.18%;"> $</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:10.98%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">28,764</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.1%;white-space:nowrap;">  </td> </tr> <tr> <td valign="bottom" style="width:42.86%;"> Series B</td> <td valign="bottom" style="width:1.08%;">  </td> <td valign="bottom" style="width:1.08%; border-bottom:solid 0.75pt #000000;">  </td> <td valign="bottom" style="width:10.98%; border-bottom:solid 0.75pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">83,598,535</td> <td valign="bottom" style="width:1.08%;white-space:nowrap;">  </td> <td valign="bottom" style="width:1.08%;">  </td> <td valign="bottom" style="width:1.08%; border-bottom:solid 0.75pt #000000;">  </td> <td valign="bottom" style="width:10.98%; border-bottom:solid 0.75pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">8,713,760</td> <td valign="bottom" style="width:1.08%;white-space:nowrap;">  </td> <td valign="bottom" style="width:1.08%;">  </td> <td valign="bottom" style="width:1.18%; border-bottom:solid 0.75pt #000000;">  </td> <td valign="bottom" style="width:10.98%; border-bottom:solid 0.75pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">30,198</td> <td valign="bottom" style="width:1.08%;white-space:nowrap;">  </td> <td valign="bottom" style="width:1.08%;">  </td> <td valign="bottom" style="width:1.18%; border-bottom:solid 0.75pt #000000;">  </td> <td valign="bottom" style="width:10.98%; border-bottom:solid 0.75pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">30,310</td> <td valign="bottom" style="width:1.1%;white-space:nowrap;">  </td> </tr> <tr> <td valign="bottom" bgcolor="#CFF0FC" style="width:42.86%;"> Total convertible preferred stock</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.08%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.08%; border-top:solid 0.75pt #000000; border-bottom:double 2.5pt #000000;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:10.98%; border-top:solid 0.75pt #000000; border-bottom:double 2.5pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">108,829,748</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.08%;white-space:nowrap;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.08%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.08%; border-top:solid 0.75pt #000000; border-bottom:double 2.5pt #000000;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:10.98%; border-top:solid 0.75pt #000000; border-bottom:double 2.5pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">11,517,222</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.08%;white-space:nowrap;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.08%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.18%; border-top:solid 0.75pt #000000; border-bottom:double 2.5pt #000000;"> $</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:10.98%; border-top:solid 0.75pt #000000; border-bottom:double 2.5pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">56,155</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.08%;white-space:nowrap;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.08%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.18%; border-top:solid 0.75pt #000000; border-bottom:double 2.5pt #000000;"> $</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:10.98%; border-top:solid 0.75pt #000000; border-bottom:double 2.5pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">59,074</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.1%;white-space:nowrap;">  </td> </tr> </table></div>  </div>

<div> The following table summarizes activity under the 2008 Plan and the 2014 Plan, including grants to nonemployees and restricted stock issued:   <div> <table border="0" cellspacing="0" cellpadding="0" align="center" style="border-collapse:collapse; width:98.3%;"> <tr> <td valign="bottom" style="width:36.46%;">  </td> <td valign="bottom" style="width:0.32%;">  </td> <td colspan="2" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:10.72%;">  </td> <td valign="bottom" style="width:0.46%;">  </td> <td colspan="2" valign="bottom" style="width:0.5%;">  </td> <td colspan="11" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:33.8%; border-bottom:solid 0.75pt #000000;"> <p style="text-align:center;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:bold;font-size:8pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">Options Issued and Outstanding</td> <td colspan="2" valign="bottom" style="width:0.9%;">  </td> <td colspan="3" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:15.12%;">  </td> <td valign="bottom" style="width:1.72%;">  </td> </tr> <tr> <td valign="bottom" style="width:36.46%;">  </td> <td valign="bottom" style="width:0.32%;">  </td> <td colspan="2" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:10.72%; border-bottom:solid 0.75pt #000000;"> <p style="text-align:center;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:bold;font-size:8pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">Shares Available for Grant</td> <td valign="bottom" style="width:0.46%;">  </td> <td colspan="2" valign="bottom" style="width:0.5%;">  </td> <td colspan="3" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:15.06%; border-bottom:solid 0.75pt #000000;"> <p style="text-align:center;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:bold;font-size:8pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">Number of Shares</td> <td colspan="2" valign="bottom" style="width:3.02%;">  </td> <td colspan="2" valign="bottom" style="width:0.52%;">  </td> <td colspan="2" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:14.58%; border-bottom:solid 0.75pt #000000;"> <p style="text-align:center;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:bold;font-size:8pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">Weighted- Average Exercise Price per Share</td> <td colspan="2" valign="bottom" style="width:0.64%;">  </td> <td colspan="2" valign="bottom" style="width:0.9%;">   </td> <td colspan="3" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:15.12%; border-bottom:solid 0.75pt #000000;"> <p style="text-align:center;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:bold;font-size:8pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">Aggregate <p style="text-align:center;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:bold;font-size:8pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">Intrinsic Value</td> <td valign="bottom" style="width:1.72%;">  </td> </tr> <tr> <td valign="bottom" style="width:36.46%;">  </td> <td valign="bottom" style="width:0.32%;">  </td> <td colspan="2" valign="bottom" style="width:10.72%; border-top:solid 0.75pt #000000;">  </td> <td valign="bottom" style="width:0.46%;">  </td> <td colspan="2" valign="bottom" style="width:0.5%;">  </td> <td colspan="3" valign="bottom" style="width:15.06%; border-top:solid 0.75pt #000000;">  </td> <td colspan="2" valign="bottom" style="width:3.02%;">  </td> <td colspan="2" valign="bottom" style="width:0.52%;">  </td> <td colspan="2" valign="bottom" style="width:14.58%; border-top:solid 0.75pt #000000;">  </td> <td colspan="2" valign="bottom" style="width:0.64%;">  </td> <td colspan="2" valign="bottom" style="width:0.9%;">   </td> <td colspan="3" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:15.12%; border-top:solid 0.75pt #000000;"> <p style="text-align:center;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:bold;font-size:8pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">(in thousands)</td> <td valign="bottom" style="width:1.72%;">  </td> </tr> <tr> <td valign="bottom" bgcolor="#CFF0FC" style="width:36.46%;"> Balances at December 31, 2011</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:0.32%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:2.54%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:8.18%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">19,798</td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:0.8%;white-space:nowrap;">  </td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:0.46%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:0.62%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:14.14%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">1,598,513</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:0.8%;white-space:nowrap;">  </td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:2.54%;">  </td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:3.38%;"> $</td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:11.76%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">0.57</td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:0.62%;white-space:nowrap;">  </td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:0.88%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.84%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:12.96%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.72%;">  </td> </tr> <tr> <td valign="bottom" style="width:36.46%;"> Options authorized</td> <td valign="bottom" style="width:0.32%;">  </td> <td valign="bottom" style="width:2.54%;">  </td> <td valign="bottom" style="width:8.18%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">114,428</td> <td colspan="2" valign="bottom" style="width:0.8%;white-space:nowrap;">  </td> <td colspan="2" valign="bottom" style="width:0.46%;">  </td> <td valign="bottom" style="width:0.62%;white-space:nowrap;">  </td> <td valign="bottom" style="width:14.14%;white-space:nowrap;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">—</td> <td valign="bottom" style="width:0.8%;white-space:nowrap;">  </td> <td colspan="2" valign="bottom" style="width:2.54%;">  </td> <td colspan="2" valign="bottom" style="width:3.38%;">  </td> <td colspan="2" valign="bottom" style="width:11.76%;">  </td> <td colspan="2" valign="bottom" style="width:0.62%;">  </td> <td colspan="2" valign="bottom" style="width:0.88%;">  </td> <td valign="bottom" style="width:1.84%;">  </td> <td valign="bottom" style="width:12.96%;">  </td> <td valign="bottom" style="width:1.72%;">  </td> </tr> <tr> <td valign="bottom" bgcolor="#CFF0FC" style="width:36.46%;"> Options granted</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:0.32%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:2.54%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:8.18%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">(81,233</td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:0.8%;white-space:nowrap;"> )</td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:0.46%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:0.62%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:14.14%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">81,233</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:0.8%;white-space:nowrap;">  </td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:2.54%;">  </td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:3.38%;">  </td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:11.76%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">3.46</td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:0.62%;white-space:nowrap;">  </td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:0.88%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.84%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:12.96%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.72%;">  </td> </tr> <tr> <td valign="bottom" style="width:36.46%;"> Options exercised</td> <td valign="bottom" style="width:0.32%;">  </td> <td valign="bottom" style="width:2.54%;white-space:nowrap;">  </td> <td valign="bottom" style="width:8.18%;white-space:nowrap;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">—</td> <td colspan="2" valign="bottom" style="width:0.8%;white-space:nowrap;">  </td> <td colspan="2" valign="bottom" style="width:0.46%;">  </td> <td valign="bottom" style="width:0.62%;">  </td> <td valign="bottom" style="width:14.14%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">(342,131</td> <td valign="bottom" style="width:0.8%;white-space:nowrap;"> )</td> <td colspan="2" valign="bottom" style="width:2.54%;">  </td> <td colspan="2" valign="bottom" style="width:3.38%;">  </td> <td colspan="2" valign="bottom" style="width:11.76%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">0.52</td> <td colspan="2" valign="bottom" style="width:0.62%;white-space:nowrap;">  </td> <td colspan="2" valign="bottom" style="width:0.88%;">  </td> <td valign="bottom" style="width:1.84%;">  </td> <td valign="bottom" style="width:12.96%;">  </td> <td valign="bottom" style="width:1.72%;">  </td> </tr> <tr> <td valign="bottom" bgcolor="#CFF0FC" style="width:36.46%; border-bottom:solid 0.75pt transparent;"> Options canceled</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:0.32%; border-bottom:solid 0.75pt transparent;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:2.54%; border-bottom:solid 0.75pt #000000;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:8.18%; border-bottom:solid 0.75pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">43,848</td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:0.8%; border-bottom:solid 0.75pt transparent;white-space:nowrap;">  </td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:0.46%; border-bottom:solid 0.75pt transparent;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:0.62%; border-bottom:solid 0.75pt #000000;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:14.14%; border-bottom:solid 0.75pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">(43,848</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:0.8%; border-bottom:solid 0.75pt transparent;white-space:nowrap;"> )</td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:2.54%; border-bottom:solid 0.75pt transparent;">  </td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:3.38%; border-bottom:solid 0.75pt transparent;">  </td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:11.76%; border-bottom:solid 0.75pt transparent;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">0.52</td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:0.62%; border-bottom:solid 0.75pt transparent;white-space:nowrap;">  </td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:0.88%; border-bottom:solid 0.75pt transparent;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.84%; border-bottom:solid 0.75pt transparent;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:12.96%; border-bottom:solid 0.75pt transparent;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.72%; border-bottom:solid 0.75pt transparent;">  </td> </tr> <tr> <td valign="bottom" style="width:36.46%;"> Balance at December 31, 2012</td> <td valign="bottom" style="width:0.32%;">  </td> <td valign="bottom" style="width:2.54%; border-top:solid 0.75pt #000000;">  </td> <td valign="bottom" style="width:8.18%; border-top:solid 0.75pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">96,841</td> <td colspan="2" valign="bottom" style="width:0.8%;white-space:nowrap;">  </td> <td colspan="2" valign="bottom" style="width:0.46%;">  </td> <td valign="bottom" style="width:0.62%; border-top:solid 0.75pt #000000;">  </td> <td valign="bottom" style="width:14.14%; border-top:solid 0.75pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">1,293,767</td> <td valign="bottom" style="width:0.8%;white-space:nowrap;">  </td> <td colspan="2" valign="bottom" style="width:2.54%;">  </td> <td colspan="2" valign="bottom" style="width:3.38%;"> $</td> <td colspan="2" valign="bottom" style="width:11.76%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">0.77</td> <td colspan="2" valign="bottom" style="width:0.62%;white-space:nowrap;">  </td> <td colspan="2" valign="bottom" style="width:0.88%;">  </td> <td valign="bottom" style="width:1.84%;">  </td> <td valign="bottom" style="width:12.96%;">  </td> <td valign="bottom" style="width:1.72%;">  </td> </tr> <tr> <td valign="bottom" bgcolor="#CFF0FC" style="width:36.46%;"> Options granted</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:0.32%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:2.54%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:8.18%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">(99,552</td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:0.8%;white-space:nowrap;"> )</td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:0.46%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:0.62%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:14.14%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">99,552</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:0.8%;white-space:nowrap;">  </td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:2.54%;">  </td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:3.38%;">  </td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:11.76%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">3.42</td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:0.62%;white-space:nowrap;">  </td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:0.88%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.84%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:12.96%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.72%;">  </td> </tr> <tr> <td valign="bottom" style="width:36.46%;"> Options exercised</td> <td valign="bottom" style="width:0.32%;">  </td> <td valign="bottom" style="width:2.54%;white-space:nowrap;">  </td> <td valign="bottom" style="width:8.18%;white-space:nowrap;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">—</td> <td colspan="2" valign="bottom" style="width:0.8%;white-space:nowrap;">  </td> <td colspan="2" valign="bottom" style="width:0.46%;">  </td> <td valign="bottom" style="width:0.62%;">  </td> <td valign="bottom" style="width:14.14%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">(223,865</td> <td valign="bottom" style="width:0.8%;white-space:nowrap;"> )</td> <td colspan="2" valign="bottom" style="width:2.54%;">  </td> <td colspan="2" valign="bottom" style="width:3.38%;">  </td> <td colspan="2" valign="bottom" style="width:11.76%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">0.56</td> <td colspan="2" valign="bottom" style="width:0.62%;white-space:nowrap;">  </td> <td colspan="2" valign="bottom" style="width:0.88%;">  </td> <td valign="bottom" style="width:1.84%;">  </td> <td valign="bottom" style="width:12.96%;">  </td> <td valign="bottom" style="width:1.72%;">  </td> </tr> <tr> <td valign="bottom" bgcolor="#CFF0FC" style="width:36.46%; border-bottom:solid 0.75pt transparent;"> Options canceled</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:0.32%; border-bottom:solid 0.75pt transparent;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:2.54%; border-bottom:solid 0.75pt #000000;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:8.18%; border-bottom:solid 0.75pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">6,625</td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:0.8%; border-bottom:solid 0.75pt transparent;white-space:nowrap;">  </td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:0.46%; border-bottom:solid 0.75pt transparent;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:0.62%; border-bottom:solid 0.75pt #000000;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:14.14%; border-bottom:solid 0.75pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">(6,625</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:0.8%; border-bottom:solid 0.75pt transparent;white-space:nowrap;"> )</td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:2.54%; border-bottom:solid 0.75pt transparent;">  </td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:3.38%; border-bottom:solid 0.75pt transparent;">  </td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:11.76%; border-bottom:solid 0.75pt transparent;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">2.23</td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:0.62%; border-bottom:solid 0.75pt transparent;white-space:nowrap;">  </td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:0.88%; border-bottom:solid 0.75pt transparent;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.84%; border-bottom:solid 0.75pt transparent;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:12.96%; border-bottom:solid 0.75pt transparent;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.72%; border-bottom:solid 0.75pt transparent;">  </td> </tr> <tr> <td valign="bottom" style="width:36.46%;"> Balance at December 31, 2013</td> <td valign="bottom" style="width:0.32%;">  </td> <td valign="bottom" style="width:2.54%; border-top:solid 0.75pt #000000;">  </td> <td valign="bottom" style="width:8.18%; border-top:solid 0.75pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">3,914</td> <td colspan="2" valign="bottom" style="width:0.8%;white-space:nowrap;">  </td> <td colspan="2" valign="bottom" style="width:0.46%;">  </td> <td valign="bottom" style="width:0.62%; border-top:solid 0.75pt #000000;">  </td> <td valign="bottom" style="width:14.14%; border-top:solid 0.75pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">1,162,829</td> <td valign="bottom" style="width:0.8%;white-space:nowrap;">  </td> <td colspan="2" valign="bottom" style="width:2.54%;">  </td> <td colspan="2" valign="bottom" style="width:3.38%;"> $</td> <td colspan="2" valign="bottom" style="width:11.76%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">1.03</td> <td colspan="2" valign="bottom" style="width:0.62%;white-space:nowrap;">  </td> <td colspan="2" valign="bottom" style="width:0.88%;">  </td> <td valign="bottom" style="width:1.84%;">  </td> <td valign="bottom" style="width:12.96%;">  </td> <td valign="bottom" style="width:1.72%;white-space:nowrap;">  </td> </tr> <tr> <td valign="bottom" bgcolor="#CFF0FC" style="width:36.46%;"> Options authorized</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:0.32%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:2.54%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:8.18%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">1,452,661</td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:0.8%;white-space:nowrap;">  </td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:0.46%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:0.62%;white-space:nowrap;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:14.14%;white-space:nowrap;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">—</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:0.8%;white-space:nowrap;">  </td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:2.54%;">  </td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:3.38%;">  </td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:11.76%;">  </td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:0.62%;">  </td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:0.88%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.84%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:12.96%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.72%;">  </td> </tr> <tr> <td valign="bottom" style="width:36.46%;"> Options granted</td> <td valign="bottom" style="width:0.32%;">  </td> <td valign="bottom" style="width:2.54%;">  </td> <td valign="bottom" style="width:8.18%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">(188,888</td> <td colspan="2" valign="bottom" style="width:0.8%;white-space:nowrap;"> )</td> <td colspan="2" valign="bottom" style="width:0.46%;">  </td> <td valign="bottom" style="width:0.62%;">  </td> <td valign="bottom" style="width:14.14%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">188,888</td> <td valign="bottom" style="width:0.8%;white-space:nowrap;">  </td> <td colspan="2" valign="bottom" style="width:2.54%;">  </td> <td colspan="2" valign="bottom" style="width:3.38%;">  </td> <td colspan="2" valign="bottom" style="width:11.76%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">24.41</td> <td colspan="2" valign="bottom" style="width:0.62%;white-space:nowrap;">  </td> <td colspan="2" valign="bottom" style="width:0.88%;">  </td> <td valign="bottom" style="width:1.84%;">  </td> <td valign="bottom" style="width:12.96%;">  </td> <td valign="bottom" style="width:1.72%;">  </td> </tr> <tr> <td valign="bottom" bgcolor="#CFF0FC" style="width:36.46%;"> Options exercised</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:0.32%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:2.54%;white-space:nowrap;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:8.18%;white-space:nowrap;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">—</td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:0.8%;white-space:nowrap;">  </td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:0.46%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:0.62%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:14.14%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">(336,398</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:0.8%;white-space:nowrap;"> )</td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:2.54%;">  </td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:3.38%;">  </td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:11.76%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">0.71</td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:0.62%;white-space:nowrap;">  </td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:0.88%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.84%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:12.96%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.72%;">  </td> </tr> <tr> <td valign="bottom" style="width:36.46%;"> Options canceled</td> <td valign="bottom" style="width:0.32%;">  </td> <td valign="bottom" style="width:2.54%;">  </td> <td valign="bottom" style="width:8.18%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">4,084</td> <td colspan="2" valign="bottom" style="width:0.8%;white-space:nowrap;">  </td> <td colspan="2" valign="bottom" style="width:0.46%;">  </td> <td valign="bottom" style="width:0.62%;">  </td> <td valign="bottom" style="width:14.14%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">(4,084</td> <td valign="bottom" style="width:0.8%;white-space:nowrap;"> )</td> <td colspan="2" valign="bottom" style="width:2.54%;">  </td> <td colspan="2" valign="bottom" style="width:3.38%;">  </td> <td colspan="2" valign="bottom" style="width:11.76%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">2.21</td> <td colspan="2" valign="bottom" style="width:0.62%;white-space:nowrap;">  </td> <td colspan="2" valign="bottom" style="width:0.88%;">  </td> <td valign="bottom" style="width:1.84%;">  </td> <td valign="bottom" style="width:12.96%;">  </td> <td valign="bottom" style="width:1.72%;">  </td> </tr> <tr> <td valign="bottom" bgcolor="#CFF0FC" style="width:36.46%;"> Options repurchased</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:0.32%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:2.54%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:8.18%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">3,511</td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:0.8%;white-space:nowrap;">  </td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:0.46%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:0.62%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:14.14%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">(3,511</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:0.8%;white-space:nowrap;"> )</td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:2.54%;">  </td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:3.38%;">  </td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:11.76%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">0.55</td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:0.62%;white-space:nowrap;">  </td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:0.88%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.84%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:12.96%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.72%;">  </td> </tr> <tr> <td valign="bottom" style="width:36.46%; border-bottom:double 2.5pt transparent;"> <p style="margin-bottom:0pt;margin-top:0pt;margin-left:36.35pt;;text-indent:-12pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">Issuance of common stock for services</td> <td valign="bottom" style="width:0.32%; border-bottom:double 2.5pt #000000;">  </td> <td valign="bottom" style="width:2.54%; border-bottom:double 2.5pt #000000;">  </td> <td valign="bottom" style="width:8.18%; border-bottom:double 2.5pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">(10,000</td> <td colspan="2" valign="bottom" style="width:0.8%; border-bottom:double 2.5pt transparent;white-space:nowrap;"> )</td> <td colspan="2" valign="bottom" style="width:0.46%; border-bottom:double 2.5pt transparent;">  </td> <td valign="bottom" style="width:0.62%; border-bottom:double 2.5pt #000000;">  </td> <td valign="bottom" style="width:14.14%; border-bottom:double 2.5pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">—</td> <td valign="bottom" style="width:0.8%; border-bottom:double 2.5pt transparent;white-space:nowrap;">  </td> <td colspan="2" valign="bottom" style="width:2.54%; border-bottom:double 2.5pt transparent;">  </td> <td colspan="2" valign="bottom" style="width:3.38%; border-bottom:double 2.5pt transparent;">  </td> <td colspan="2" valign="bottom" style="width:11.76%; border-bottom:double 2.5pt transparent;"> <p style="text-align:right;margin-top:0pt;margin-bottom:0pt;margin-left:0pt;;text-indent:0pt;;font-size:8pt;font-weight:normal;font-style:normal;font-family:Times New Roman;text-transform:none;font-variant: normal;">—</td> <td colspan="2" valign="bottom" style="width:0.62%; border-bottom:double 2.5pt transparent;">  </td> <td colspan="2" valign="bottom" style="width:0.88%; border-bottom:double 2.5pt transparent;">  </td> <td valign="bottom" style="width:1.84%; border-bottom:double 2.5pt transparent;">  </td> <td valign="bottom" style="width:12.96%; border-bottom:double 2.5pt transparent;">  </td> <td valign="bottom" style="width:1.72%; border-bottom:double 2.5pt transparent;">  </td> </tr> <tr> <td valign="bottom" bgcolor="#CFF0FC" style="width:36.46%; border-bottom:double 2.5pt transparent;"> Balance at December 31, 2014</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:0.32%; border-top:double 2.5pt #000000; border-bottom:double 2.5pt transparent;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:2.54%; border-top:double 2.5pt #000000; border-bottom:double 2.5pt #000000;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:8.18%; border-top:solid 0.75pt #000000; border-bottom:double 2.5pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">1,265,282</td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:0.8%; border-bottom:double 2.5pt transparent;white-space:nowrap;">  </td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:0.46%; border-bottom:double 2.5pt transparent;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:0.62%; border-top:solid 0.75pt #000000; border-bottom:double 2.5pt #000000;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:14.14%; border-top:solid 0.75pt #000000; border-bottom:double 2.5pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">1,007,724</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:0.8%; border-bottom:double 2.5pt transparent;white-space:nowrap;">  </td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:2.54%; border-bottom:double 2.5pt transparent;">  </td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:3.38%; border-bottom:double 2.5pt transparent;"> $</td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:11.76%; border-bottom:double 2.5pt transparent;"> <p style="text-align:right;margin-top:0pt;margin-bottom:0pt;margin-left:0pt;;text-indent:0pt;;font-size:10pt;font-weight:normal;font-style:normal;font-family:Times New Roman;text-transform:none;font-variant: normal;">5.51</td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:0.62%; border-bottom:double 2.5pt transparent;">  </td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:0.88%; border-bottom:double 2.5pt transparent;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.84%; border-bottom:double 2.5pt transparent;"> $</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:12.96%; border-bottom:double 2.5pt transparent;"> <p style="text-align:right;margin-top:0pt;margin-bottom:0pt;margin-left:0pt;;text-indent:0pt;;font-size:10pt;font-weight:normal;font-style:normal;font-family:Times New Roman;text-transform:none;font-variant: normal;">14,839</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.72%; border-bottom:double 2.5pt transparent;">  </td> </tr> <tr> <td valign="bottom" style="width:36.46%; border-bottom:double 2.5pt transparent;"> Vested and expected to vest at December 31, 2014</td> <td valign="bottom" style="width:0.32%; border-bottom:double 2.5pt transparent;">  </td> <td valign="bottom" style="width:2.54%; border-top:double 2.5pt #000000; border-bottom:double 2.5pt transparent;">  </td> <td valign="bottom" style="width:8.18%; border-top:double 2.5pt #000000; border-bottom:double 2.5pt transparent;">  </td> <td colspan="2" valign="bottom" style="width:0.8%; border-bottom:double 2.5pt transparent;">  </td> <td colspan="2" valign="bottom" style="width:0.46%; border-bottom:double 2.5pt transparent;">  </td> <td valign="bottom" style="width:0.62%; border-top:double 2.5pt #000000; border-bottom:double 2.5pt #000000;"> <p style="margin-top:0pt;padding-top:1pt;text-align:center;border-top:nil 0pt;margin-bottom:0pt;margin-left:0pt;;text-indent:0pt;;font-size:10pt;font-family:Times New Roman;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;"> </td> <td valign="bottom" style="width:14.14%; border-top:double 2.5pt #000000; border-bottom:double 2.5pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">990,889</td> <td valign="bottom" style="width:0.8%; border-bottom:double 2.5pt transparent;">  </td> <td colspan="2" valign="bottom" style="width:2.54%; border-bottom:double 2.5pt transparent;">  </td> <td colspan="2" valign="bottom" style="width:3.38%; border-bottom:double 2.5pt transparent;"> $</td> <td colspan="2" valign="bottom" style="width:11.76%; border-bottom:double 2.5pt transparent;"> <p style="text-align:right;margin-top:0pt;margin-bottom:0pt;margin-left:0pt;;text-indent:0pt;;font-size:10pt;font-weight:normal;font-style:normal;font-family:Times New Roman;text-transform:none;font-variant: normal;">5.27</td> <td colspan="2" valign="bottom" style="width:0.62%; border-bottom:double 2.5pt transparent;">  </td> <td colspan="2" valign="bottom" style="width:0.88%; border-bottom:double 2.5pt transparent;">  </td> <td valign="bottom" style="width:1.84%; border-bottom:double 2.5pt transparent;"> $</td> <td valign="bottom" style="width:12.96%; border-bottom:double 2.5pt transparent;"> <p style="text-align:right;margin-top:0pt;margin-bottom:0pt;margin-left:0pt;;text-indent:0pt;;font-size:10pt;font-weight:normal;font-style:normal;font-family:Times New Roman;text-transform:none;font-variant: normal;">14,746</td> <td valign="bottom" style="width:1.72%; border-bottom:double 2.5pt transparent;">  </td> </tr> <tr> <td valign="bottom" bgcolor="#CFF0FC" style="width:36.46%; border-bottom:double 2.5pt transparent;"> Vested at December 31, 2014</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:0.32%; border-bottom:double 2.5pt transparent;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:2.54%; border-bottom:double 2.5pt transparent;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:8.18%; border-bottom:double 2.5pt transparent;">  </td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:0.8%; border-bottom:double 2.5pt transparent;">  </td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:0.46%; border-bottom:double 2.5pt transparent;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:0.62%; border-top:double 2.5pt #000000; border-bottom:double 2.5pt #000000;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:14.14%; border-top:double 2.5pt #000000; border-bottom:double 2.5pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">643,217</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:0.8%; border-bottom:double 2.5pt transparent;white-space:nowrap;">  </td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:2.54%; border-bottom:double 2.5pt transparent;">  </td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:3.38%; border-bottom:double 2.5pt transparent;"> $</td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:11.76%; border-bottom:double 2.5pt transparent;"> <p style="text-align:right;margin-top:0pt;margin-bottom:0pt;margin-left:0pt;;text-indent:0pt;;font-size:10pt;font-weight:normal;font-style:normal;font-family:Times New Roman;text-transform:none;font-variant: normal;">1.21</td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:0.62%; border-bottom:double 2.5pt transparent;">  </td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:0.88%; border-bottom:double 2.5pt transparent;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.84%; border-bottom:double 2.5pt transparent;"> $</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:12.96%; border-bottom:double 2.5pt transparent;"> <p style="text-align:right;margin-top:0pt;margin-bottom:0pt;margin-left:0pt;;text-indent:0pt;;font-size:10pt;font-weight:normal;font-style:normal;font-family:Times New Roman;text-transform:none;font-variant: normal;">11,376</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.72%; border-bottom:double 2.5pt transparent;">  </td> </tr> </table></div>  </div>

<div> The following table illustrates the weighted-average assumptions for the Black-Scholes option-pricing model used in determining the fair value of ESPP purchase rights granted to employees:</div><div> <div> <table border="0" cellspacing="0" cellpadding="0" align="center" style="border-collapse:collapse; width:55.52%;"> <tr> <td valign="bottom" style="width:73.86%;">  </td> <td valign="bottom" style="width:1.02%;">  </td> <td colspan="4" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:23.34%;"> <p style="text-align:center;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:bold;font-size:8pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">Year Ended December 31, 2014</td> </tr> <tr> <td valign="bottom" bgcolor="#CFF0FC" style="width:73.86%;"> Expected term (years)</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.02%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.04%; border-top:solid 0.75pt #000000;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:17.88%; border-top:solid 0.75pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">0.5</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:3.02%; border-top:solid 0.75pt #000000;white-space:nowrap;">  </td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:1.5%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.68%;">  </td> </tr> <tr> <td valign="bottom" style="width:73.86%;"> Volatility</td> <td valign="bottom" style="width:1.02%;">  </td> <td valign="bottom" style="width:1.04%;">  </td> <td valign="bottom" style="width:17.88%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">73</td> <td valign="bottom" style="width:3.02%;white-space:nowrap;"> %</td> <td colspan="2" valign="bottom" style="width:1.5%;">  </td> <td valign="bottom" style="width:1.68%;">  </td> </tr> <tr> <td valign="bottom" bgcolor="#CFF0FC" style="width:73.86%;"> Risk-free interest rate</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.02%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.04%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:17.88%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">0.05</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:3.02%;white-space:nowrap;"> %</td> <td colspan="2" valign="bottom" bgcolor="#CFF0FC" style="width:1.5%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.68%;">  </td> </tr> <tr style="height:3.35pt;"> <td valign="bottom" style="width:73.86%;"> Dividend yield</td> <td valign="bottom" style="width:1.02%;">  </td> <td valign="bottom" style="width:1.04%;">  </td> <td valign="bottom" style="width:17.88%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">—</td> <td valign="bottom" style="width:3.02%;white-space:nowrap;"> %</td> <td colspan="2" valign="bottom" style="width:1.5%;">  </td> <td valign="bottom" style="width:1.68%;">  </td> </tr> </table></div>  </div>

<div> Total stock-based compensation recognized was as follows (in thousands):   <div> <table border="0" cellspacing="0" cellpadding="0" align="center" style="border-collapse:collapse; width:80%;"> <tr> <td valign="bottom" style="width:51.84%;">  </td> <td valign="bottom" style="width:1.22%;">  </td> <td colspan="10" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:45.7%; border-bottom:solid 1pt #000000;"> <p style="text-align:center;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:bold;font-size:8pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">Year Ended December 31,</td> <td valign="bottom" style="width:1.24%;">  </td> </tr> <tr> <td valign="bottom" style="width:51.84%;">  </td> <td valign="bottom" style="width:1.22%;">  </td> <td colspan="2" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:13.58%; border-bottom:solid 0.75pt #000000;"> <p style="text-align:center;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:bold;font-size:8pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">2014</td> <td valign="bottom" style="width:1.24%;">  </td> <td valign="bottom" style="width:1.24%;">   </td> <td colspan="2" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:13.58%; border-bottom:solid 0.75pt #000000;"> <p style="text-align:center;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:bold;font-size:8pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">2013</td> <td valign="bottom" style="width:1.24%;">  </td> <td valign="bottom" style="width:1.24%;">   </td> <td colspan="2" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:13.58%; border-bottom:solid 0.75pt #000000;"> <p style="text-align:center;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:bold;font-size:8pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">2012</td> <td valign="bottom" style="width:1.24%;">  </td> </tr> <tr> <td valign="bottom" style="width:51.84%;">  </td> <td valign="bottom" style="width:1.22%;">  </td> <td colspan="2" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:13.58%;">  </td> <td valign="bottom" style="width:1.24%;">  </td> <td valign="bottom" style="width:1.24%;">  </td> <td colspan="2" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:13.58%;"> <p style="text-align:center;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:bold;font-size:8pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">(in thousands)</td> <td valign="bottom" style="width:1.24%;">  </td> <td valign="bottom" style="width:1.24%;">  </td> <td colspan="2" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:13.58%;">  </td> <td valign="bottom" style="width:1.24%;">  </td> </tr> <tr> <td valign="bottom" bgcolor="#CFF0FC" style="width:51.84%;"> Research and development</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.22%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.24%;"> $</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:12.34%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">1,376</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.24%;white-space:nowrap;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.24%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.24%;"> $</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:12.34%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">200</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.24%;white-space:nowrap;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.24%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.24%;"> $</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:12.34%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">221</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.24%;white-space:nowrap;">  </td> </tr> <tr> <td valign="bottom" style="width:51.84%; border-bottom:solid 0.75pt transparent;"> General and administrative</td> <td valign="bottom" style="width:1.22%; border-bottom:solid 0.75pt transparent;">  </td> <td valign="bottom" style="width:1.24%; border-bottom:solid 0.75pt #000000;">  </td> <td valign="bottom" style="width:12.34%; border-bottom:solid 0.75pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">316</td> <td valign="bottom" style="width:1.24%; border-bottom:solid 0.75pt transparent;white-space:nowrap;">  </td> <td valign="bottom" style="width:1.24%; border-bottom:solid 0.75pt transparent;">  </td> <td valign="bottom" style="width:1.24%; border-bottom:solid 0.75pt #000000;">  </td> <td valign="bottom" style="width:12.34%; border-bottom:solid 0.75pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">152</td> <td valign="bottom" style="width:1.24%; border-bottom:solid 0.75pt transparent;white-space:nowrap;">  </td> <td valign="bottom" style="width:1.24%; border-bottom:solid 0.75pt transparent;">  </td> <td valign="bottom" style="width:1.24%; border-bottom:solid 0.75pt #000000;">  </td> <td valign="bottom" style="width:12.34%; border-bottom:solid 0.75pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">252</td> <td valign="bottom" style="width:1.24%; border-bottom:solid 0.75pt transparent;white-space:nowrap;">  </td> </tr> <tr> <td valign="bottom" bgcolor="#CFF0FC" style="width:51.84%; border-bottom:double 2.5pt transparent;"> Total stock-based compensation</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.22%; border-bottom:double 2.5pt transparent;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.24%; border-top:solid 0.75pt #000000; border-bottom:double 2.5pt #000000;"> $</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:12.34%; border-top:solid 0.75pt #000000; border-bottom:double 2.5pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">1,692</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.24%; border-bottom:double 2.5pt transparent;white-space:nowrap;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.24%; border-bottom:double 2.5pt transparent;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.24%; border-top:solid 0.75pt #000000; border-bottom:double 2.5pt #000000;"> $</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:12.34%; border-top:solid 0.75pt #000000; border-bottom:double 2.5pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">352</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.24%; border-bottom:double 2.5pt transparent;white-space:nowrap;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.24%; border-bottom:double 2.5pt transparent;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.24%; border-top:solid 0.75pt #000000; border-bottom:double 2.5pt #000000;"> $</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:12.34%; border-top:solid 0.75pt #000000; border-bottom:double 2.5pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">473</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.24%; border-bottom:double 2.5pt transparent;white-space:nowrap;">  </td> </tr> </table></div>  </div>

<div> The fair value of stock option awards to employees was estimated at the date of grant using a Black-Scholes option-pricing model with the following weighted-average assumptions:   <div> <table border="0" cellspacing="0" cellpadding="0" align="center" style="border-collapse:collapse; width:80%;"> <tr> <td valign="bottom" style="width:42%;">  </td> <td valign="bottom" style="width:1%;">  </td> <td colspan="10" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:1%; border-bottom:solid 1pt #000000;"> <p style="text-align:center;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:bold;font-size:8pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">Year Ended December 31</td> <td valign="bottom" style="width:1%;">  </td> </tr> <tr> <td valign="bottom" style="width:42%;">  </td> <td valign="bottom" style="width:1%;">  </td> <td colspan="2" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:1%; border-bottom:solid 1pt #000000;"> <p style="text-align:center;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:bold;font-size:8pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">2014</td> <td valign="bottom" style="width:1%;">  </td> <td valign="bottom" style="width:1%;">  </td> <td colspan="2" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:1%; border-bottom:solid 1pt #000000;"> <p style="text-align:center;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:bold;font-size:8pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">2013</td> <td valign="bottom" style="width:1%;">  </td> <td valign="bottom" style="width:1%;">  </td> <td colspan="2" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:1%; border-bottom:solid 1pt #000000;"> <p style="text-align:center;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:bold;font-size:8pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">2012</td> <td valign="bottom" style="width:1%;">  </td> </tr> <tr> <td valign="bottom" bgcolor="#CFF0FC" style="width:42%;"> Expected term (years)</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:10%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">5.97</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;white-space:nowrap;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:10%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">6.07</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;white-space:nowrap;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:10%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">5.73</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;white-space:nowrap;">  </td> </tr> <tr> <td valign="bottom" style="width:42%;"> Volatility</td> <td valign="bottom" style="width:1%;">  </td> <td valign="bottom" style="width:1%;">  </td> <td valign="bottom" style="width:10%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">94</td> <td valign="bottom" style="width:1%;white-space:nowrap;"> %</td> <td valign="bottom" style="width:1%;">  </td> <td valign="bottom" style="width:1%;">  </td> <td valign="bottom" style="width:10%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">98</td> <td valign="bottom" style="width:1%;white-space:nowrap;"> %</td> <td valign="bottom" style="width:1%;">  </td> <td valign="bottom" style="width:1%;">  </td> <td valign="bottom" style="width:10%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">97</td> <td valign="bottom" style="width:1%;white-space:nowrap;"> %</td> </tr> <tr> <td valign="bottom" bgcolor="#CFF0FC" style="width:42%;"> Risk-free interest rate</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:10%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">1.79</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;white-space:nowrap;"> %</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:10%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">1.35</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;white-space:nowrap;"> %</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:10%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">0.79</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;white-space:nowrap;"> %</td> </tr> <tr style="height:3.35pt;"> <td valign="bottom" style="width:42%;"> Dividend yield</td> <td valign="bottom" style="width:1%;">  </td> <td valign="bottom" style="width:1%;">  </td> <td valign="bottom" style="width:10%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">—</td> <td valign="bottom" style="width:1%;white-space:nowrap;"> %</td> <td valign="bottom" style="width:1%;">  </td> <td valign="bottom" style="width:1%;">  </td> <td valign="bottom" style="width:10%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">—</td> <td valign="bottom" style="width:1%;white-space:nowrap;"> %</td> <td valign="bottom" style="width:1%;">  </td> <td valign="bottom" style="width:1%;">  </td> <td valign="bottom" style="width:10%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">—</td> <td valign="bottom" style="width:1%;white-space:nowrap;"> %</td> </tr> </table></div>  </div>

<div> The following is a reconciliation of the statutory federal income tax rate to the Company’s effective tax rate:   <div> <table border="0" cellspacing="0" cellpadding="0" align="center" style="border-collapse:collapse; width:80%;"> <tr> <td valign="bottom" style="width:42%;">  </td> <td valign="bottom" style="width:1%;">  </td> <td colspan="10" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:1%; border-bottom:solid 1pt #000000;"> <p style="text-align:center;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:bold;font-size:8pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">Year Ended December 31,</td> <td valign="bottom" style="width:1%;">  </td> </tr> <tr> <td valign="bottom" style="width:42%;">  </td> <td valign="bottom" style="width:1%;">  </td> <td colspan="2" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:1%; border-bottom:solid 1pt #000000;"> <p style="text-align:center;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:bold;font-size:8pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">2014</td> <td valign="bottom" style="width:1%;">  </td> <td valign="bottom" style="width:1%;">  </td> <td colspan="2" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:1%; border-bottom:solid 1pt #000000;"> <p style="text-align:center;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:bold;font-size:8pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">2013</td> <td valign="bottom" style="width:1%;">  </td> <td valign="bottom" style="width:1%;">  </td> <td colspan="2" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:1%; border-bottom:solid 1pt #000000;"> <p style="text-align:center;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:bold;font-size:8pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">2012</td> <td valign="bottom" style="width:1%;">  </td> </tr> <tr> <td valign="bottom" bgcolor="#CFF0FC" style="width:42%;"> Expected income tax provision at the federal statutory rate</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:10%;"> <p style="margin-top:0pt;text-align:right;margin-bottom:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">35.0</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;white-space:nowrap;"> <p style="text-align:left;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:normal;font-style:normal;font-family:Times New Roman;font-size:10pt;text-transform:none;font-variant: normal;">%</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:10%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">35.0</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;white-space:nowrap;"> %</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:10%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">35.0</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;white-space:nowrap;"> %</td> </tr> <tr> <td valign="bottom" style="width:42%;"> State taxes, net of federal benefit</td> <td valign="bottom" style="width:1%;">  </td> <td valign="bottom" style="width:1%;">  </td> <td valign="bottom" style="width:10%;"> <p style="margin-top:0pt;text-align:right;margin-bottom:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">4.6</td> <td valign="bottom" style="width:1%;white-space:nowrap;">  </td> <td valign="bottom" style="width:1%;">  </td> <td valign="bottom" style="width:1%;">  </td> <td valign="bottom" style="width:10%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">(1.4</td> <td valign="bottom" style="width:1%;white-space:nowrap;"> )</td> <td valign="bottom" style="width:1%;">  </td> <td valign="bottom" style="width:1%;">  </td> <td valign="bottom" style="width:10%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">—</td> <td valign="bottom" style="width:1%;white-space:nowrap;">  </td> </tr> <tr> <td valign="bottom" bgcolor="#CFF0FC" style="width:42%;"> Change in valuation allowance</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:10%;"> <p style="margin-top:0pt;text-align:right;margin-bottom:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">(17.9</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;white-space:nowrap;"> )</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:10%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">(22.6</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;white-space:nowrap;"> )</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:10%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">(38.6</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;white-space:nowrap;"> )</td> </tr> <tr> <td valign="bottom" style="width:42%;"> Nondeductible expenses</td> <td valign="bottom" style="width:1%;">  </td> <td valign="bottom" style="width:1%;">  </td> <td valign="bottom" style="width:10%;"> <p style="margin-top:0pt;text-align:right;margin-bottom:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">(20.6</td> <td valign="bottom" style="width:1%;white-space:nowrap;"> <p style="text-align:left;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:normal;font-style:normal;font-family:Times New Roman;font-size:10pt;text-transform:none;font-variant: normal;">)</td> <td valign="bottom" style="width:1%;">  </td> <td valign="bottom" style="width:1%;">  </td> <td valign="bottom" style="width:10%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">(20.8</td> <td valign="bottom" style="width:1%;white-space:nowrap;"> )</td> <td valign="bottom" style="width:1%;">  </td> <td valign="bottom" style="width:1%;">  </td> <td valign="bottom" style="width:10%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">(5.2</td> <td valign="bottom" style="width:1%;white-space:nowrap;"> )</td> </tr> <tr> <td valign="bottom" bgcolor="#CFF0FC" style="width:42%;"> Tax credits</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:10%;"> <p style="margin-top:0pt;text-align:right;margin-bottom:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">—</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;white-space:nowrap;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:10%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">7.3</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;white-space:nowrap;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:10%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">4.4</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;white-space:nowrap;">  </td> </tr> <tr> <td valign="bottom" style="width:42%; border-bottom:solid 0.75pt transparent;"> Other</td> <td valign="bottom" style="width:1%; border-bottom:solid 0.75pt transparent;">  </td> <td valign="bottom" style="width:1%; border-bottom:solid 0.75pt #000000;">  </td> <td valign="bottom" style="width:10%; border-bottom:solid 0.75pt #000000;"> <p style="margin-top:0pt;text-align:right;margin-bottom:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">(3.2</td> <td valign="bottom" style="width:1%; border-bottom:solid 0.75pt transparent;white-space:nowrap;"> <p style="text-align:left;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:normal;font-style:normal;font-family:Times New Roman;font-size:10pt;text-transform:none;font-variant: normal;">)</td> <td valign="bottom" style="width:1%; border-bottom:solid 0.75pt transparent;">  </td> <td valign="bottom" style="width:1%; border-bottom:solid 0.75pt #000000;">  </td> <td valign="bottom" style="width:10%; border-bottom:solid 0.75pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">0.3</td> <td valign="bottom" style="width:1%; border-bottom:solid 0.75pt transparent;white-space:nowrap;">  </td> <td valign="bottom" style="width:1%; border-bottom:solid 0.75pt transparent;">  </td> <td valign="bottom" style="width:1%; border-bottom:solid 0.75pt #000000;">  </td> <td valign="bottom" style="width:10%; border-bottom:solid 0.75pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">4.4</td> <td valign="bottom" style="width:1%; border-bottom:solid 0.75pt transparent;white-space:nowrap;">  </td> </tr> <tr> <td valign="bottom" bgcolor="#CFF0FC" style="width:42%; border-bottom:double 2.5pt transparent;"> Income tax provision</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%; border-bottom:double 2.5pt transparent;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%; border-top:solid 0.75pt #000000; border-bottom:double 2.5pt #000000;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:10%; border-top:solid 0.75pt #000000; border-bottom:double 2.5pt #000000;"> <p style="margin-top:0pt;text-align:right;margin-bottom:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">(2.1</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%; border-bottom:double 2.5pt transparent;white-space:nowrap;"> )%</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%; border-bottom:double 2.5pt transparent;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%; border-top:solid 0.75pt #000000; border-bottom:double 2.5pt #000000;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:10%; border-top:solid 0.75pt #000000; border-bottom:double 2.5pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">(2.2</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%; border-bottom:double 2.5pt transparent;white-space:nowrap;"> )%</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%; border-bottom:double 2.5pt transparent;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%; border-top:solid 0.75pt #000000; border-bottom:double 2.5pt #000000;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:10%; border-top:solid 0.75pt #000000; border-bottom:double 2.5pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">—</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%; border-bottom:double 2.5pt transparent;white-space:nowrap;"> %</td> </tr> </table></div>  </div>

<div> Significant components of the Company’s deferred tax assets are as follows:   <div> <table border="0" cellspacing="0" cellpadding="0" align="center" style="border-collapse:collapse; width:70%;"> <tr> <td valign="bottom" style="width:63.4%;">  </td> <td valign="bottom" style="width:1.42%;">  </td> <td colspan="6" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:33.8%; border-bottom:solid 1pt #000000;"> <p style="text-align:center;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:bold;font-size:8pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">December 31,</td> <td valign="bottom" style="width:1.4%;">  </td> </tr> <tr> <td valign="bottom" style="width:63.4%;">  </td> <td valign="bottom" style="width:1.42%;">  </td> <td colspan="2" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:15.5%; border-bottom:solid 0.75pt #000000;"> <p style="text-align:center;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:bold;font-size:8pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">2014</td> <td valign="bottom" style="width:1.4%;">  </td> <td valign="bottom" style="width:1.4%;">   </td> <td colspan="2" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:15.48%; border-bottom:solid 0.75pt #000000;"> <p style="text-align:center;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:bold;font-size:8pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">2013</td> <td valign="bottom" style="width:1.4%;">  </td> </tr> <tr> <td valign="bottom" style="width:63.4%;">  </td> <td valign="bottom" style="width:1.42%;">  </td> <td colspan="2" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:15.5%;">  </td> <td valign="bottom" style="width:1.4%;">  </td> <td valign="bottom" style="width:1.4%;">  </td> <td colspan="2" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:15.48%;">  </td> <td valign="bottom" style="width:1.4%;">  </td> </tr> <tr> <td valign="bottom" style="width:63.4%;">  </td> <td valign="bottom" style="width:1.42%;">  </td> <td colspan="6" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:33.8%;"> <p style="text-align:center;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:bold;font-size:8pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">(in thousands)</td> <td valign="bottom" style="width:1.4%;">  </td> </tr> <tr> <td valign="bottom" bgcolor="#CFF0FC" style="width:63.4%;"> Deferred tax assets:</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.42%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.42%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:14.1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.4%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.4%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.4%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:14.08%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.4%;">  </td> </tr> <tr> <td valign="bottom" style="width:63.4%;"> Net operating loss carryforwards</td> <td valign="bottom" style="width:1.42%;">  </td> <td valign="bottom" style="width:1.42%;"> $</td> <td valign="bottom" style="width:14.1%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">11,262</td> <td valign="bottom" style="width:1.4%;white-space:nowrap;">  </td> <td valign="bottom" style="width:1.4%;">  </td> <td valign="bottom" style="width:1.4%;"> $</td> <td valign="bottom" style="width:14.08%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">13,069</td> <td valign="bottom" style="width:1.4%;white-space:nowrap;">  </td> </tr> <tr> <td valign="bottom" bgcolor="#CFF0FC" style="width:63.4%;"> Deferred revenue</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.42%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.42%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:14.1%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">11,099</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.4%;white-space:nowrap;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.4%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.4%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:14.08%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">9,723</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.4%;white-space:nowrap;">  </td> </tr> <tr> <td valign="bottom" style="width:63.4%;"> Research credits</td> <td valign="bottom" style="width:1.42%;">  </td> <td valign="bottom" style="width:1.42%;">  </td> <td valign="bottom" style="width:14.1%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">1,260</td> <td valign="bottom" style="width:1.4%;white-space:nowrap;">  </td> <td valign="bottom" style="width:1.4%;">  </td> <td valign="bottom" style="width:1.4%;">  </td> <td valign="bottom" style="width:14.08%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">1,734</td> <td valign="bottom" style="width:1.4%;white-space:nowrap;">  </td> </tr> <tr> <td valign="bottom" bgcolor="#CFF0FC" style="width:63.4%;"> Other</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.42%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.42%; border-bottom:solid 0.75pt #000000;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:14.1%; border-bottom:solid 0.75pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">1,201</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.4%;white-space:nowrap;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.4%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.4%; border-bottom:solid 0.75pt #000000;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:14.08%; border-bottom:solid 0.75pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">475</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.4%;white-space:nowrap;">  </td> </tr> <tr> <td valign="bottom" style="width:63.4%;"> Gross deferred tax assets</td> <td valign="bottom" style="width:1.42%;">  </td> <td valign="bottom" style="width:1.42%; border-top:solid 0.75pt #000000;">  </td> <td valign="bottom" style="width:14.1%; border-top:solid 0.75pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">24,822</td> <td valign="bottom" style="width:1.4%;white-space:nowrap;">  </td> <td valign="bottom" style="width:1.4%;">  </td> <td valign="bottom" style="width:1.4%; border-top:solid 0.75pt #000000;">  </td> <td valign="bottom" style="width:14.08%; border-top:solid 0.75pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">25,001</td> <td valign="bottom" style="width:1.4%;white-space:nowrap;">  </td> </tr> <tr> <td valign="bottom" bgcolor="#CFF0FC" style="width:63.4%;"> Valuation allowance</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.42%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.42%; border-bottom:solid 0.75pt #000000;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:14.1%; border-bottom:solid 0.75pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">(24,741</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.4%; border-bottom:solid 0.75pt #000000;white-space:nowrap;"> )</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.4%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.4%; border-bottom:solid 0.75pt #000000;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:14.08%; border-bottom:solid 0.75pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">(25,001</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.4%;white-space:nowrap;"> )</td> </tr> <tr> <td valign="bottom" style="width:63.4%;"> Total deferred tax assets </td> <td valign="bottom" style="width:1.42%;">  </td> <td valign="bottom" style="width:1.42%; border-top:solid 0.75pt #000000;">  </td> <td valign="bottom" style="width:14.1%; border-top:solid 0.75pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">81</td> <td valign="bottom" style="width:1.4%; border-top:solid 0.75pt #000000;white-space:nowrap;">  </td> <td valign="bottom" style="width:1.4%;">  </td> <td valign="bottom" style="width:1.4%; border-top:solid 0.75pt #000000;white-space:nowrap;">  </td> <td valign="bottom" style="width:14.08%; border-top:solid 0.75pt #000000;white-space:nowrap;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">—</td> <td valign="bottom" style="width:1.4%;white-space:nowrap;">  </td> </tr> <tr> <td valign="bottom" bgcolor="#CFF0FC" style="width:63.4%;"> Deferred tax liabilities</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.42%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.42%; border-bottom:solid 0.75pt #000000;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:14.1%; border-bottom:solid 0.75pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">(81</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.4%;white-space:nowrap;"> )</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.4%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.4%; border-bottom:solid 0.75pt #000000;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:14.08%; border-bottom:solid 0.75pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">—</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.4%;white-space:nowrap;">  </td> </tr> <tr> <td valign="bottom" style="width:63.4%;"> Net deferred tax assets</td> <td valign="bottom" style="width:1.42%;">  </td> <td valign="bottom" style="width:1.42%; border-top:solid 0.75pt #000000; border-bottom:double 2.5pt #000000;"> $</td> <td valign="bottom" style="width:14.1%; border-top:solid 0.75pt #000000; border-bottom:double 2.5pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">—</td> <td valign="bottom" style="width:1.4%;white-space:nowrap;">  </td> <td valign="bottom" style="width:1.4%;">  </td> <td valign="bottom" style="width:1.4%; border-top:solid 0.75pt #000000; border-bottom:double 2.5pt #000000;white-space:nowrap;"> $</td> <td valign="bottom" style="width:14.08%; border-top:solid 0.75pt #000000; border-bottom:double 2.5pt #000000;white-space:nowrap;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">—</td> <td valign="bottom" style="width:1.4%;white-space:nowrap;">  </td> </tr> </table></div>  </div>

<div> A reconciliation of the beginning and ending amount of unrecognized tax benefits is as follows:   <div> <table border="0" cellspacing="0" cellpadding="0" align="center" style="border-collapse:collapse; width:80%;"> <tr> <td valign="bottom" style="width:51.8%;">  </td> <td valign="bottom" style="width:1.22%;">  </td> <td colspan="10" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:45.76%; border-bottom:solid 1pt #000000;"> <p style="text-align:center;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:bold;font-size:8pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">December 31,</td> <td valign="bottom" style="width:1.22%;">  </td> </tr> <tr> <td valign="bottom" style="width:51.8%;">  </td> <td valign="bottom" style="width:1.22%;">  </td> <td colspan="2" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:13.62%; border-bottom:solid 0.75pt #000000;"> <p style="text-align:center;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:bold;font-size:8pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">2014</td> <td valign="bottom" style="width:1.22%;">  </td> <td valign="bottom" style="width:1.22%;">   </td> <td colspan="2" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:13.66%; border-bottom:solid 0.75pt #000000;"> <p style="text-align:center;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:bold;font-size:8pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">2013</td> <td valign="bottom" style="width:1.22%;">  </td> <td valign="bottom" style="width:1.22%;">   </td> <td colspan="2" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:13.64%; border-bottom:solid 0.75pt #000000;"> <p style="text-align:center;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:bold;font-size:8pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">2012</td> <td valign="bottom" style="width:1.22%;">  </td> </tr> <tr> <td valign="bottom" style="width:51.8%;">  </td> <td valign="bottom" style="width:1.22%;">  </td> <td colspan="2" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:13.62%;">  </td> <td valign="bottom" style="width:1.22%;">  </td> <td valign="bottom" style="width:1.22%;">  </td> <td colspan="2" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:13.66%;"> <p style="text-align:center;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:bold;font-size:8pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">(in thousands)</td> <td valign="bottom" style="width:1.22%;">  </td> <td valign="bottom" style="width:1.22%;">  </td> <td colspan="2" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:13.64%;">  </td> <td valign="bottom" style="width:1.22%;">  </td> </tr> <tr> <td valign="bottom" bgcolor="#CFF0FC" style="width:51.8%;"> Balance at beginning of year</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.22%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.32%;"> $</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:12.3%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">1,411</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.22%;white-space:nowrap;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.22%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.32%;"> $</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:12.32%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">1,064</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.22%;white-space:nowrap;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.22%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.32%;"> $</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:12.32%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">807</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.22%;white-space:nowrap;">  </td> </tr> <tr> <td valign="bottom" style="width:51.8%;"> Additions based on tax positions related to prior year</td> <td valign="bottom" style="width:1.22%;">  </td> <td valign="bottom" style="width:1.32%;">  </td> <td valign="bottom" style="width:12.3%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">405</td> <td valign="bottom" style="width:1.22%;white-space:nowrap;">  </td> <td valign="bottom" style="width:1.22%;">  </td> <td valign="bottom" style="width:1.32%;">  </td> <td valign="bottom" style="width:12.32%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">—</td> <td valign="bottom" style="width:1.22%;white-space:nowrap;">  </td> <td valign="bottom" style="width:1.22%;">  </td> <td valign="bottom" style="width:1.32%;">  </td> <td valign="bottom" style="width:12.32%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">—</td> <td valign="bottom" style="width:1.22%;white-space:nowrap;">  </td> </tr> <tr> <td valign="bottom" bgcolor="#CFF0FC" style="width:51.8%; border-bottom:solid 0.75pt transparent;"> Additions based on tax positions related to current year</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.22%; border-bottom:solid 0.75pt transparent;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.32%; border-bottom:solid 0.75pt #000000;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:12.3%; border-bottom:solid 0.75pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">999</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.22%; border-bottom:solid 0.75pt transparent;white-space:nowrap;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.22%; border-bottom:solid 0.75pt transparent;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.32%; border-bottom:solid 0.75pt #000000;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:12.32%; border-bottom:solid 0.75pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">347</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.22%; border-bottom:solid 0.75pt transparent;white-space:nowrap;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.22%; border-bottom:solid 0.75pt transparent;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.32%; border-bottom:solid 0.75pt #000000;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:12.32%; border-bottom:solid 0.75pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">257</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.22%; border-bottom:solid 0.75pt transparent;white-space:nowrap;">  </td> </tr> <tr> <td valign="bottom" style="width:51.8%; border-bottom:double 2.5pt transparent;"> Balance at end of year</td> <td valign="bottom" style="width:1.22%; border-bottom:double 2.5pt transparent;">  </td> <td valign="bottom" style="width:1.32%; border-top:solid 0.75pt #000000; border-bottom:double 2.5pt #000000;"> $</td> <td valign="bottom" style="width:12.3%; border-top:solid 0.75pt #000000; border-bottom:double 2.5pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">2,815</td> <td valign="bottom" style="width:1.22%; border-bottom:double 2.5pt transparent;white-space:nowrap;">  </td> <td valign="bottom" style="width:1.22%; border-bottom:double 2.5pt transparent;">  </td> <td valign="bottom" style="width:1.32%; border-top:solid 0.75pt #000000; border-bottom:double 2.5pt #000000;"> $</td> <td valign="bottom" style="width:12.32%; border-top:solid 0.75pt #000000; border-bottom:double 2.5pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">1,411</td> <td valign="bottom" style="width:1.22%; border-bottom:double 2.5pt transparent;white-space:nowrap;">  </td> <td valign="bottom" style="width:1.22%; border-bottom:double 2.5pt transparent;">  </td> <td valign="bottom" style="width:1.32%; border-top:solid 0.75pt #000000; border-bottom:double 2.5pt #000000;"> $</td> <td valign="bottom" style="width:12.32%; border-top:solid 0.75pt #000000; border-bottom:double 2.5pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">1,064</td> <td valign="bottom" style="width:1.22%; border-bottom:double 2.5pt transparent;white-space:nowrap;">  </td> </tr> </table></div>  </div>

<div> The following table sets forth the computation of net loss per common share (in thousands, except share and per share amounts):   <div> <table border="0" cellspacing="0" cellpadding="0" align="center" style="border-collapse:collapse; width:80%;"> <tr> <td valign="bottom" style="width:42%;">  </td> <td valign="bottom" style="width:1%;">  </td> <td colspan="10" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:1%; border-bottom:solid 1pt #000000;"> <p style="text-align:center;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:bold;font-size:8pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">December 31,</td> <td valign="bottom" style="width:1%;">  </td> </tr> <tr> <td valign="bottom" style="width:42%;">  </td> <td valign="bottom" style="width:1%;">  </td> <td colspan="2" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:1%; border-bottom:solid 1pt #000000;"> <p style="text-align:center;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:bold;font-size:8pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">2014</td> <td valign="bottom" style="width:1%;">  </td> <td valign="bottom" style="width:1%;">   </td> <td colspan="2" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:1%; border-bottom:solid 1pt #000000;"> <p style="text-align:center;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:bold;font-size:8pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">2013</td> <td valign="bottom" style="width:1%;">  </td> <td valign="bottom" style="width:1%;">   </td> <td colspan="2" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:1%; border-bottom:solid 1pt #000000;"> <p style="text-align:center;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:bold;font-size:8pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">2012</td> <td valign="bottom" style="width:1%;">  </td> </tr> <tr> <td valign="bottom" bgcolor="#CFF0FC" style="width:42%;"> Numerator:</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:10%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:10%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:10%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;">  </td> </tr> <tr> <td valign="bottom" style="width:42%; border-bottom:double 2.5pt transparent;"> Net loss</td> <td valign="bottom" style="width:1%; border-bottom:double 2.5pt transparent;">  </td> <td valign="bottom" style="width:1%; border-bottom:double 2.5pt #000000;"> $</td> <td valign="bottom" style="width:10%; border-bottom:double 2.5pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">(3,214</td> <td valign="bottom" style="width:1%; border-bottom:double 2.5pt transparent;white-space:nowrap;"> )</td> <td valign="bottom" style="width:1%; border-bottom:double 2.5pt transparent;">  </td> <td valign="bottom" style="width:1%; border-bottom:double 2.5pt #000000;"> $</td> <td valign="bottom" style="width:10%; border-bottom:double 2.5pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">(6,564</td> <td valign="bottom" style="width:1%; border-bottom:double 2.5pt transparent;white-space:nowrap;"> )</td> <td valign="bottom" style="width:1%; border-bottom:double 2.5pt transparent;">  </td> <td valign="bottom" style="width:1%; border-bottom:double 2.5pt #000000;"> $</td> <td valign="bottom" style="width:10%; border-bottom:double 2.5pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">(9,785</td> <td valign="bottom" style="width:1%; border-bottom:double 2.5pt transparent;white-space:nowrap;"> )</td> </tr> <tr> <td valign="bottom" bgcolor="#CFF0FC" style="width:42%;"> Denominator:</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%; border-top:double 2.5pt #000000;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:10%; border-top:double 2.5pt #000000;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%; border-top:double 2.5pt #000000;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:10%; border-top:double 2.5pt #000000;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%; border-top:double 2.5pt #000000;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:10%; border-top:double 2.5pt #000000;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;">  </td> </tr> <tr> <td valign="bottom" style="width:42%; border-bottom:solid 0.75pt transparent;"> Weighted average number of shares outstanding—basic and diluted</td> <td valign="bottom" style="width:1%; border-bottom:solid 0.75pt transparent;">  </td> <td valign="bottom" style="width:1%; border-bottom:solid 0.75pt #000000;">  </td> <td valign="bottom" style="width:10%; border-bottom:solid 0.75pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">10,248,337</td> <td valign="bottom" style="width:1%; border-bottom:solid 0.75pt transparent;white-space:nowrap;">  </td> <td valign="bottom" style="width:1%; border-bottom:solid 0.75pt transparent;">  </td> <td valign="bottom" style="width:1%; border-bottom:solid 0.75pt #000000;">  </td> <td valign="bottom" style="width:10%; border-bottom:solid 0.75pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">1,127,948</td> <td valign="bottom" style="width:1%; border-bottom:solid 0.75pt transparent;white-space:nowrap;">  </td> <td valign="bottom" style="width:1%; border-bottom:solid 0.75pt transparent;">  </td> <td valign="bottom" style="width:1%; border-bottom:solid 0.75pt #000000;">  </td> <td valign="bottom" style="width:10%; border-bottom:solid 0.75pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">864,020</td> <td valign="bottom" style="width:1%; border-bottom:solid 0.75pt transparent;white-space:nowrap;">  </td> </tr> <tr> <td valign="bottom" bgcolor="#CFF0FC" style="width:42%; border-bottom:double 2.5pt transparent;"> Net loss per share—basic and diluted</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%; border-bottom:double 2.5pt transparent;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%; border-top:solid 0.75pt #000000; border-bottom:double 2.5pt #000000;"> $</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:10%; border-top:solid 0.75pt #000000; border-bottom:double 2.5pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">(0.31</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%; border-bottom:double 2.5pt transparent;white-space:nowrap;"> )</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%; border-bottom:double 2.5pt transparent;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%; border-top:solid 0.75pt #000000; border-bottom:double 2.5pt #000000;"> $</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:10%; border-top:solid 0.75pt #000000; border-bottom:double 2.5pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">(5.82</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%; border-bottom:double 2.5pt transparent;white-space:nowrap;"> )</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%; border-bottom:double 2.5pt transparent;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%; border-top:solid 0.75pt #000000; border-bottom:double 2.5pt #000000;"> $</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:10%; border-top:solid 0.75pt #000000; border-bottom:double 2.5pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">(11.32</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%; border-bottom:double 2.5pt transparent;white-space:nowrap;"> )</td> </tr> </table></div>  </div>

<div> Potentially dilutive securities that were not included in the diluted per share calculations because they would be anti-dilutive were as follows:   <div> <table border="0" cellspacing="0" cellpadding="0" align="center" style="border-collapse:collapse; width:80%;"> <tr> <td valign="bottom" style="width:42%;">  </td> <td valign="bottom" style="width:1%;">  </td> <td colspan="10" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:1%; border-bottom:solid 1pt #000000;"> <p style="text-align:center;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:bold;font-size:8pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">December 31,</td> <td valign="bottom" style="width:1%;">  </td> </tr> <tr> <td valign="bottom" style="width:42%;">  </td> <td valign="bottom" style="width:1%;">  </td> <td colspan="2" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:1%; border-bottom:solid 1pt #000000;"> <p style="text-align:center;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:bold;font-size:8pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">2014</td> <td valign="bottom" style="width:1%;">  </td> <td valign="bottom" style="width:1%;">   </td> <td colspan="2" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:1%; border-bottom:solid 1pt #000000;"> <p style="text-align:center;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:bold;font-size:8pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">2013</td> <td valign="bottom" style="width:1%;">  </td> <td valign="bottom" style="width:1%;">   </td> <td colspan="2" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:1%; border-bottom:solid 1pt #000000;"> <p style="text-align:center;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:bold;font-size:8pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">2012</td> <td valign="bottom" style="width:1%;">  </td> </tr> <tr> <td valign="bottom" bgcolor="#CFF0FC" style="width:42%;"> Convertible preferred stock</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:10%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">—</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;white-space:nowrap;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:10%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">11,517,222</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;white-space:nowrap;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:10%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">11,517,222</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%;white-space:nowrap;">  </td> </tr> <tr> <td valign="bottom" style="width:42%;"> Options to purchase common stock</td> <td valign="bottom" style="width:1%;">  </td> <td valign="bottom" style="width:1%;">  </td> <td valign="bottom" style="width:10%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">1,007,724</td> <td valign="bottom" style="width:1%;white-space:nowrap;">  </td> <td valign="bottom" style="width:1%;">  </td> <td valign="bottom" style="width:1%;">  </td> <td valign="bottom" style="width:10%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">1,162,829</td> <td valign="bottom" style="width:1%;white-space:nowrap;">  </td> <td valign="bottom" style="width:1%;">  </td> <td valign="bottom" style="width:1%;">  </td> <td valign="bottom" style="width:10%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">1,293,767</td> <td valign="bottom" style="width:1%;white-space:nowrap;">  </td> </tr> <tr> <td valign="bottom" bgcolor="#CFF0FC" style="width:42%; border-bottom:solid 0.75pt transparent;"> Warrants to purchase convertible preferred stock</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%; border-bottom:solid 0.75pt transparent;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%; border-bottom:solid 0.75pt #000000;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:10%; border-bottom:solid 0.75pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">—</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%; border-bottom:solid 0.75pt transparent;white-space:nowrap;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%; border-bottom:solid 0.75pt transparent;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%; border-bottom:solid 0.75pt #000000;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:10%; border-bottom:solid 0.75pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">574,953</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%; border-bottom:solid 0.75pt transparent;white-space:nowrap;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%; border-bottom:solid 0.75pt transparent;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%; border-bottom:solid 0.75pt #000000;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:10%; border-bottom:solid 0.75pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">574,953</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1%; border-bottom:solid 0.75pt transparent;white-space:nowrap;">  </td> </tr> <tr> <td valign="bottom" style="width:42%; border-bottom:double 2.5pt transparent;"> Total</td> <td valign="bottom" style="width:1%; border-bottom:double 2.5pt transparent;">  </td> <td valign="bottom" style="width:1%; border-top:solid 0.75pt #000000; border-bottom:double 2.5pt #000000;">  </td> <td valign="bottom" style="width:10%; border-top:solid 0.75pt #000000; border-bottom:double 2.5pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">1,007,724</td> <td valign="bottom" style="width:1%; border-bottom:double 2.5pt transparent;white-space:nowrap;">  </td> <td valign="bottom" style="width:1%; border-bottom:double 2.5pt transparent;">  </td> <td valign="bottom" style="width:1%; border-top:solid 0.75pt #000000; border-bottom:double 2.5pt #000000;">  </td> <td valign="bottom" style="width:10%; border-top:solid 0.75pt #000000; border-bottom:double 2.5pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">13,255,004</td> <td valign="bottom" style="width:1%; border-bottom:double 2.5pt transparent;white-space:nowrap;">  </td> <td valign="bottom" style="width:1%; border-bottom:double 2.5pt transparent;">  </td> <td valign="bottom" style="width:1%; border-top:solid 0.75pt #000000; border-bottom:double 2.5pt #000000;">  </td> <td valign="bottom" style="width:10%; border-top:solid 0.75pt #000000; border-bottom:double 2.5pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">13,385,942</td> <td valign="bottom" style="width:1%; border-bottom:double 2.5pt transparent;white-space:nowrap;">  </td> </tr> </table></div>  </div>

<div> The future minimum payments under the noncancelable operating lease at December 31, 2014, are as follows (in thousands):   <div> <table border="0" cellspacing="0" cellpadding="0" align="center" style="border-collapse:collapse; width:60%;"> <tr> <td valign="bottom" style="width:75.44%; border-bottom:solid 1pt #000000;white-space:nowrap;"> Year ending December 31,</td> <td valign="bottom" style="width:1.64%;">  </td> <td colspan="2" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:21.32%; border-bottom:solid 1pt #000000;"> <p style="text-align:center;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:bold;font-size:8pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">Amounts</td> <td valign="bottom" style="width:1.62%;">  </td> </tr> <tr> <td valign="bottom" bgcolor="#CFF0FC" style="width:75.44%; border-top:solid 1pt #000000;"> 2015</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.64%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.64%;"> $</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:19.68%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">843</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.62%;white-space:nowrap;">  </td> </tr> <tr> <td valign="bottom" style="width:75.44%;"> 2016</td> <td valign="bottom" style="width:1.64%;">  </td> <td valign="bottom" style="width:1.64%;">  </td> <td valign="bottom" style="width:19.68%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">868</td> <td valign="bottom" style="width:1.62%;white-space:nowrap;">  </td> </tr> <tr> <td valign="bottom" bgcolor="#CFF0FC" style="width:75.44%;"> 2017</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.64%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.64%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:19.68%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">895</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.62%;white-space:nowrap;">  </td> </tr> <tr> <td valign="bottom" style="width:75.44%;"> 2018</td> <td valign="bottom" style="width:1.64%;">  </td> <td valign="bottom" style="width:1.64%;">  </td> <td valign="bottom" style="width:19.68%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">921</td> <td valign="bottom" style="width:1.62%;white-space:nowrap;">  </td> </tr> <tr> <td valign="bottom" bgcolor="#CFF0FC" style="width:75.44%; border-bottom:solid 0.75pt transparent;"> 2019</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.64%; border-bottom:solid 0.75pt transparent;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.64%; border-bottom:solid 0.75pt #000000;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:19.68%; border-bottom:solid 0.75pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">653</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.62%; border-bottom:solid 0.75pt transparent;white-space:nowrap;">  </td> </tr> <tr> <td valign="bottom" style="width:75.44%; border-bottom:double 2.5pt transparent;"> <p style="margin-bottom:0pt;margin-top:0pt;margin-left:36pt;;text-indent:-12.25pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">Total</td> <td valign="bottom" style="width:1.64%; border-bottom:double 2.5pt transparent;">  </td> <td valign="bottom" style="width:1.64%; border-top:solid 0.75pt #000000; border-bottom:double 2.5pt #000000;"> $</td> <td valign="bottom" style="width:19.68%; border-top:solid 0.75pt #000000; border-bottom:double 2.5pt #000000;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">4,180</td> <td valign="bottom" style="width:1.62%; border-bottom:double 2.5pt transparent;white-space:nowrap;">  </td> </tr> </table></div>  </div>

<div> Selected quarterly financial results from operations for the years ended December 31, 2014 and 2013 are as follows (in thousands, except per share amounts):   <div> <table border="0" cellspacing="0" cellpadding="0" align="center" style="border-collapse:collapse; width:90%;"> <tr> <td valign="bottom" style="width:42.88%;">  </td> <td valign="bottom" style="width:1.1%;">  </td> <td colspan="14" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:54.92%; border-bottom:solid 1pt #000000;"> <p style="text-align:center;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:bold;font-size:8pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">2014 Quarter End</td> <td valign="bottom" style="width:1.1%;">  </td> </tr> <tr> <td valign="bottom" style="width:42.88%;">  </td> <td valign="bottom" style="width:1.1%;">  </td> <td colspan="2" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:12.08%; border-bottom:solid 1pt #000000;"> <p style="text-align:center;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:bold;font-size:8pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">March 31,</td> <td valign="bottom" style="width:1.1%;">  </td> <td valign="bottom" style="width:1.1%;">   </td> <td colspan="2" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:12.08%; border-bottom:solid 1pt #000000;"> <p style="text-align:center;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:bold;font-size:8pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">June 30</td> <td valign="bottom" style="width:1.1%;">  </td> <td valign="bottom" style="width:1.1%;">   </td> <td colspan="2" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:12.08%; border-bottom:solid 1pt #000000;"> <p style="text-align:center;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:bold;font-size:8pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">September 30</td> <td valign="bottom" style="width:1.1%;">  </td> <td valign="bottom" style="width:1.1%;">   </td> <td colspan="2" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:12.08%; border-bottom:solid 1pt #000000;"> <p style="text-align:center;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:bold;font-size:8pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">December 31</td> <td valign="bottom" style="width:1.1%;">  </td> </tr> <tr> <td valign="bottom" bgcolor="#CFF0FC" style="width:42.88%;"> Total revenue</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.1%;"> $</td> <td valign="top" bgcolor="#CFF0FC" style="width:10.98%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">8,550</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.1%;white-space:nowrap;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.1%;"> $</td> <td valign="top" bgcolor="#CFF0FC" style="width:10.98%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">9,137</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.1%;white-space:nowrap;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.1%;"> $</td> <td valign="top" bgcolor="#CFF0FC" style="width:10.98%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">7,598</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.1%;white-space:nowrap;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.1%;"> $</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:10.98%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">6,338</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.1%;white-space:nowrap;">  </td> </tr> <tr> <td valign="bottom" style="width:42.88%;"> Operating expenses</td> <td valign="bottom" style="width:1.1%;">  </td> <td valign="bottom" style="width:1.1%;">  </td> <td valign="top" style="width:10.98%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">9,014</td> <td valign="bottom" style="width:1.1%;white-space:nowrap;">  </td> <td valign="bottom" style="width:1.1%;">  </td> <td valign="bottom" style="width:1.1%;">  </td> <td valign="top" style="width:10.98%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">6,386</td> <td valign="bottom" style="width:1.1%;white-space:nowrap;">  </td> <td valign="bottom" style="width:1.1%;">  </td> <td valign="bottom" style="width:1.1%;">  </td> <td valign="top" style="width:10.98%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">7,517</td> <td valign="bottom" style="width:1.1%;white-space:nowrap;">  </td> <td valign="bottom" style="width:1.1%;">  </td> <td valign="bottom" style="width:1.1%;">  </td> <td valign="bottom" style="width:10.98%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">10,270</td> <td valign="bottom" style="width:1.1%;white-space:nowrap;">  </td> </tr> <tr> <td valign="bottom" bgcolor="#CFF0FC" style="width:42.88%;"> Net income (loss)</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.1%;">  </td> <td valign="top" bgcolor="#CFF0FC" style="width:10.98%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">(3,071</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.1%;white-space:nowrap;"> )</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.1%;">  </td> <td valign="top" bgcolor="#CFF0FC" style="width:10.98%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">3,753</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.1%;white-space:nowrap;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.1%;">  </td> <td valign="top" bgcolor="#CFF0FC" style="width:10.98%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">74</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.1%;white-space:nowrap;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:10.98%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">(3,970</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.1%;white-space:nowrap;"> )</td> </tr> <tr> <td valign="bottom" style="width:42.88%;"> Net income (loss) per share:</td> <td valign="bottom" style="width:1.1%;">  </td> <td valign="bottom" style="width:1.1%;">  </td> <td valign="top" style="width:10.98%;">  </td> <td valign="bottom" style="width:1.1%;">  </td> <td valign="bottom" style="width:1.1%;">  </td> <td valign="bottom" style="width:1.1%;">  </td> <td valign="top" style="width:10.98%;">  </td> <td valign="bottom" style="width:1.1%;">  </td> <td valign="bottom" style="width:1.1%;">  </td> <td valign="bottom" style="width:1.1%;">  </td> <td valign="top" style="width:10.98%;">  </td> <td valign="bottom" style="width:1.1%;">  </td> <td valign="bottom" style="width:1.1%;">  </td> <td valign="bottom" style="width:1.1%;">  </td> <td valign="bottom" style="width:10.98%;">  </td> <td valign="bottom" style="width:1.1%;">  </td> </tr> <tr> <td valign="bottom" bgcolor="#CFF0FC" style="width:42.88%;"> Basic</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.1%;">  </td> <td valign="top" bgcolor="#CFF0FC" style="width:10.98%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">(2.44</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.1%;white-space:nowrap;"> )</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.1%;">  </td> <td valign="top" bgcolor="#CFF0FC" style="width:10.98%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">0.20</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.1%;white-space:nowrap;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.1%;">  </td> <td valign="top" bgcolor="#CFF0FC" style="width:10.98%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">—</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.1%;white-space:nowrap;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:10.98%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">(0.21</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.1%;white-space:nowrap;"> )</td> </tr> <tr> <td valign="bottom" style="width:42.88%;"> Diluted</td> <td valign="bottom" style="width:1.1%;">  </td> <td valign="bottom" style="width:1.1%;">  </td> <td valign="top" style="width:10.98%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">(2.44</td> <td valign="bottom" style="width:1.1%;white-space:nowrap;"> )</td> <td valign="bottom" style="width:1.1%;">  </td> <td valign="bottom" style="width:1.1%;">  </td> <td valign="top" style="width:10.98%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">0.18</td> <td valign="bottom" style="width:1.1%;white-space:nowrap;">  </td> <td valign="bottom" style="width:1.1%;">  </td> <td valign="bottom" style="width:1.1%;">  </td> <td valign="top" style="width:10.98%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">—</td> <td valign="bottom" style="width:1.1%;white-space:nowrap;">  </td> <td valign="bottom" style="width:1.1%;">  </td> <td valign="bottom" style="width:1.1%;">  </td> <td valign="bottom" style="width:10.98%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">(0.21</td> <td valign="bottom" style="width:1.1%;white-space:nowrap;"> )</td> </tr> </table></div>   <div> <table border="0" cellspacing="0" cellpadding="0" align="center" style="border-collapse:collapse; width:90%;"> <tr> <td valign="bottom" style="width:42.88%;">  </td> <td valign="bottom" style="width:1.1%;">  </td> <td colspan="14" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:54.92%; border-bottom:solid 1pt #000000;"> <p style="text-align:center;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:bold;font-size:8pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">2013 Quarter End</td> <td valign="bottom" style="width:1.1%;">  </td> </tr> <tr> <td valign="bottom" style="width:42.88%;">  </td> <td valign="bottom" style="width:1.1%;">  </td> <td colspan="2" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:12.08%; border-bottom:solid 1pt #000000;"> <p style="text-align:center;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:bold;font-size:8pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">March 31,</td> <td valign="bottom" style="width:1.1%;">  </td> <td valign="bottom" style="width:1.1%;">   </td> <td colspan="2" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:12.08%; border-bottom:solid 1pt #000000;"> <p style="text-align:center;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:bold;font-size:8pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">June 30</td> <td valign="bottom" style="width:1.1%;">  </td> <td valign="bottom" style="width:1.1%;">   </td> <td colspan="2" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:12.08%; border-bottom:solid 1pt #000000;"> <p style="text-align:center;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:bold;font-size:8pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">September 30</td> <td valign="bottom" style="width:1.1%;">  </td> <td valign="bottom" style="width:1.1%;">   </td> <td colspan="2" valign="bottom" style="padding-left:0.7pt;padding-Right:0.7pt;padding-Top:0pt;padding-Bottom:0pt;width:12.08%; border-bottom:solid 1pt #000000;"> <p style="text-align:center;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-weight:bold;font-size:8pt;font-family:Times New Roman;font-style:normal;text-transform:none;font-variant: normal;">December 31</td> <td valign="bottom" style="width:1.1%;">  </td> </tr> <tr> <td valign="bottom" bgcolor="#CFF0FC" style="width:42.88%;"> Total revenue</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.1%;"> $</td> <td valign="top" bgcolor="#CFF0FC" style="width:10.98%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">6,556</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.1%;white-space:nowrap;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.1%;"> $</td> <td valign="top" bgcolor="#CFF0FC" style="width:10.98%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">7,291</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.1%;white-space:nowrap;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.1%;"> $</td> <td valign="top" bgcolor="#CFF0FC" style="width:10.98%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">6,593</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.1%;white-space:nowrap;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.1%;"> $</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:10.98%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">8,488</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.1%;white-space:nowrap;">  </td> </tr> <tr> <td valign="bottom" style="width:42.88%;"> Operating expenses</td> <td valign="bottom" style="width:1.1%;">  </td> <td valign="bottom" style="width:1.1%;">  </td> <td valign="top" style="width:10.98%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">6,966</td> <td valign="bottom" style="width:1.1%;white-space:nowrap;">  </td> <td valign="bottom" style="width:1.1%;">  </td> <td valign="bottom" style="width:1.1%;">  </td> <td valign="top" style="width:10.98%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">8,142</td> <td valign="bottom" style="width:1.1%;white-space:nowrap;">  </td> <td valign="bottom" style="width:1.1%;">  </td> <td valign="bottom" style="width:1.1%;">  </td> <td valign="top" style="width:10.98%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">7,479</td> <td valign="bottom" style="width:1.1%;white-space:nowrap;">  </td> <td valign="bottom" style="width:1.1%;">  </td> <td valign="bottom" style="width:1.1%;">  </td> <td valign="bottom" style="width:10.98%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">9,206</td> <td valign="bottom" style="width:1.1%;white-space:nowrap;">  </td> </tr> <tr> <td valign="bottom" bgcolor="#CFF0FC" style="width:42.88%;"> Net loss</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.1%;">  </td> <td valign="top" bgcolor="#CFF0FC" style="width:10.98%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">(470</td> <td valign="top" bgcolor="#CFF0FC" style="width:1.1%;white-space:nowrap;"> )</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.1%;">  </td> <td valign="top" bgcolor="#CFF0FC" style="width:10.98%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">(891</td> <td valign="top" bgcolor="#CFF0FC" style="width:1.1%;white-space:nowrap;"> )</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.1%;">  </td> <td valign="top" bgcolor="#CFF0FC" style="width:10.98%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">(934</td> <td valign="top" bgcolor="#CFF0FC" style="width:1.1%;white-space:nowrap;"> )</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.1%;">  </td> <td valign="bottom" bgcolor="#CFF0FC" style="width:10.98%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">(4,269</td> <td valign="bottom" bgcolor="#CFF0FC" style="width:1.1%;white-space:nowrap;"> )</td> </tr> <tr> <td valign="bottom" style="width:42.88%;"> Basic and diluted net loss per common share</td> <td valign="bottom" style="width:1.1%;">  </td> <td valign="bottom" style="width:1.1%;">  </td> <td valign="top" style="width:10.98%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">(0.45</td> <td valign="top" style="width:1.1%;white-space:nowrap;"> )</td> <td valign="bottom" style="width:1.1%;">  </td> <td valign="bottom" style="width:1.1%;">  </td> <td valign="top" style="width:10.98%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">(0.81</td> <td valign="top" style="width:1.1%;white-space:nowrap;"> )</td> <td valign="bottom" style="width:1.1%;">  </td> <td valign="bottom" style="width:1.1%;">  </td> <td valign="top" style="width:10.98%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">(0.81</td> <td valign="top" style="width:1.1%;white-space:nowrap;"> )</td> <td valign="bottom" style="width:1.1%;">  </td> <td valign="bottom" style="width:1.1%;">  </td> <td valign="bottom" style="width:10.98%;"> <p style="text-align:right;margin-bottom:0pt;margin-top:0pt;margin-left:0pt;;text-indent:0pt;;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">(3.53</td> <td valign="bottom" style="width:1.1%;white-space:nowrap;"> )</td> </tr> </table></div>  </div>

2007-10-17 Delaware

On June 18, 2014, the Company’s Amended and Restated Certificate of Incorporation became effective resulting in a reverse split of the Company’s common stock and convertible preferred stock at a 1-for-9 ratio (the “Reverse Stock Split”). The par value and the authorized shares of the common stock and convertible preferred stock were not adjusted as a result of the Reverse Stock Split. All issued and outstanding common stock, convertible preferred stock, warrants for preferred stock, options for common stock and per share amounts contained in the financial statements have been retroactively adjusted to reflect this Reverse Stock Split for all periods presented.

0.11

4928900

642900

61200000

7800000

11517222

56200000

305000000

300000000

5000000

90 days or less

100000

P3Y

P5Y

105410000

100000

105510000

105410000

100000

32472000

180000

32652000

32472000

180000

6456000

0.20 0.10 0.70

2950000

3506000

6456000

1593000

8049000

3039000

2315000

229000

91000

362000

2135000

1456000

5765000

3862000

3634000

3332000

20000000

30000000

40000000

0.01 0.02 0.03 P60D

35000000

15000000

25000000

795000000 197500000 597500000

18400000

8100000

3200000

13200000

20900000

2200000

47100000

200000

1250000

196800000

25231213

83598535

2803462 8713760 11517222

25957000

30198000

28764000

30310000

59074000

574953

0.09

P4Y

1419328

35221

1454549

1153279

0.040

10683053 743569

19798

114428

81233

43848

96841

99552

6625

3914

1452661

188888

4084

3511

10000

1265282

1598513

342131

43848

1293767

223865

6625

1162829

336398

4084

3511 0

1007724

990889

643217

0.57

3.46

0.52

0.77

3.42

0.56

2.23

1.03

24.41

0.71

2.21

0.55 0

5.51

5.27

1.21

14839000

14746000

11376000

18.53

2.68

2.56

18.89

202762

0.010

2230374 2014-09-01 2015-02-27 185892

202762

P6M

0.73

0.0005

0.00

286217

0.27 1.08 0

58969

800000

1376000

200000

221000

316000

152000

252000

3200000

P2Y3M18D

P5Y11M19D

P6Y26D

P5Y8M23D

0.94

0.98

0.97

0.0179

0.0135

0.0079

0.00

18.57

2.68

2.56

20.77

3.43

10000

3333

100000

2000

P3Y

0.350

0.046

-0.014

0.179

0.226

0.386

0.206

0.208

0.052

0.073

0.044

-0.032

0.003

0.044

-0.021

-0.022

0.00

11262000

13069000

11099000

9723000

1260000

1734000

1201000

475000

24822000

25001000

24741000

25001000

81000

-300000

1500000

28000000

25600000

expire beginning in 2028 expire beginning in 2018

2100000

2300000

2029

1411000

1064000

807000

405000

999000

347000

257000

2815000

2800000

1400000

1100000

11517222

1007724

1162829

1293767

574953

1007724

13255004

13385942

200000

100000

2016-09-30

2019-09-30

600000

100000

843000

868000

895000

921000

653000

4180000

600000

500000

400000

700000

1200000

P90D

8550000

9137000

7598000

6338000

9014000

6386000

7517000

10270000

-3071000

3753000

74000

-3970000

-2.44

0.20

-0.21

-2.44

0.18

-0.21

6556000

7291000

6593000

8488000

6966000

8142000

7479000

9206000

-470000

-891000

-934000

-4269000

-0.45

-0.81

-3.53